Oligonucleotide N3'-->P5' phosphoramidates as potential therapeutic agents.

[1]  D. Bartel,et al.  RNA-catalysed nucleotide synthesis , 1998, Nature.

[2]  W. Wilson,et al.  NMR solution structure of the N3' --> P5' phosphoramidate duplex d(CGCGAATTCGCG)2 by the iterative relaxation matrix approach. , 1998, Biochemistry.

[3]  S. Gryaznov,et al.  RNA mimetics: oligoribonucleotide N3'-->P5' phosphoramidates. , 1998, Nucleic acids research.

[4]  S. Gryaznov.  Synthesis and Properties of the Oligonucleotide N3′ →P5′ Phosphoramidates , 1997 .

[5]  E. Taillandier,et al.  A physico-chemical study of triple helix formation by an oligodeoxythymidylate with N3'--> P5' phosphoramidate linkages. , 1997, Nucleic acids research.

[6]  G. F. Joyce,et al.  A general purpose RNA-cleaving DNA enzyme. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[7]  B. Calabretta,et al.  Antileukemia effect of c-myc N3'-->P5' phosphoramidate antisense oligonucleotides in vivo. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[8]  M. Nerenberg,et al.  RNase H-independent antisense activity of oligonucleotide N3 '--> P5 ' phosphoramidates. , 1997, Nucleic acids research.

[9]  D. Lloyd,et al.  Structural RNA mimetics: N3'-->P5' phosphoramidate DNA analogs of HIV-1 RRE and TAR RNA form A-type helices that bind specifically to Rev and Tat-related peptides. , 1997, Biochemistry.

[10]  C. Giovannangeli,et al.  Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a target. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[11]  C. Giovannangeli,et al.  Efficient inhibition of transcription elongation in vitro by oligonucleotide phosphoramidates targeted to proviral HIV DNA. , 1996, Journal of molecular biology.

[12]  R. Schultz,et al.  Oligo-2'-fluoro-2'-deoxynucleotide N3'-->P5' phosphoramidates: synthesis and properties. , 1996, Nucleic acids research.

[13]  D. Lloyd,et al.  Stable triple helices formed by oligonucleotide N3'-->P5' phosphoramidates inhibit transcription elongation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[14]  D. Lloyd,et al.  Synthesis of oligodeoxyribonucleotide N3'-->P5' phosphoramidates. , 1995, Nucleic acids research.

[15]  L. DeDionisio,et al.  Analysis of a ribonuclease H digestion of N3'-->P5' phosphoramidate-RNA duplexes by capillary gel electrophoresis. , 1995, Journal of chromatography. B, Biomedical applications.

[16]  R. Christoffersen,et al.  Ribozymes as human therapeutic agents. , 1995, Journal of medicinal chemistry.

[17]  S. Gryaznov,et al.  Oligodeoxyribonucleotide N3'.fwdarw.P5' Phosphoramidates: synthesis and Hybridization Properties , 1994 .

[18]  D. Crothers,et al.  Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition. , 1992, Science.

[19]  E. Ohtsuka,et al.  Oligo(2′‐O‐methyl)ribonucleotides Effective probes for duplex DNA , 1992, FEBS letters.

[20]  J. Toulmé,et al.  Specific regulation of gene expression by antisense, sense and antigene nucleic acids. , 1990, Biochimica et biophysica acta.

[21]  E. Uhlmann,et al.  Antisense oligonucleotides: a new therapeutic principle , 1990 .

[22]  K. Jankowski,et al.  Nucleoside conformation is determined by the electronegativity of the sugar substituent. , 1980, Nucleic acids research.

[23]  M. Egli,et al.  Consequences of Replacing the DNA 3‘-Oxygen by an Amino Group: High-Resolution Crystal Structure of a Fully Modified N3‘ → P5‘ Phosphoramidate DNA Dodecamer Duplex† , 1998 .

[24]  T. Fitzwater,et al.  Potent 2′-amino-, and 2′-fluoro-2′- deoxyribonucleotide RNA inhibitors of keratinocyte growth factor , 1997, Nature Biotechnology.

[25]  D. Lloyd,et al.  An oligodeoxyribonucleotide N3'--> P5' phosphoramidate duplex forms an A-type helix in solution. , 1996, Nucleic acids research.

[26]  Sergei M. Gr yaznov,et al.  8 Oligonucleotide N3 ′ (cid:1) P5 ′ phosphoramidates as antisense , 1996 .

[27]  L. J. Maher,et al.  Exclusion of RNA strands from a purine motif triple helix. , 1994, Nucleic acids research.