Histopathology of Otitis Media in Infants with Cleft and High-Arched Palates

The middle ear and the bony and cartilaginous portions of the eustachian tube (ET) were studied histopathologically in 20 temporal bones from 19 infants, aged 45 minutes to 12 months. Otitis media (OM) was observed in 17 of 20 bones, and 16 bones with OM had an effusion. Otitis media was more severe in the ears of cleft palate infants compared to those with high-arched palates. Inflammation was present in the bony portion of the ET in 15 of 17 temporal bones with OM, but appeared to be less marked than that present in the middle ear. In addition, inflammation of the cartilaginous portion of the ET appeared to be less severe than in its bony portion. Inflammation of the middle ear and the ET appeared to be more pronounced in older infants, particularly in those with cleft palates.

[1]  S. R. Rood,et al.  An extreme morphologic variation of the auditory tube cartilage: a case report. , 1981, The Cleft palate journal.

[2]  W. Doyle,et al.  Eustachian Tube Function in Cleft Palate Children , 1980, The Annals of otology, rhinology & laryngology. Supplement.

[3]  T. Ishii,et al.  Histopathological Study of Otitis Media with Effusion , 1980, The Annals of otology, rhinology & laryngology. Supplement.

[4]  G. Zechner.  Auditory Tube and Middle Ear Mucosa in Nonpurulent Otitis Media , 1980, The Annals of otology, rhinology & laryngology. Supplement.

[5]  W. Doyle,et al.  Nonhuman Primate Model of Cleft Palate and its Implications for Middle Ear Pathology , 1980, The Annals of otology, rhinology & laryngology. Supplement.

[6]  M. Tos.  Pathogenesis and Pathology of Chronic Secretory Otitis Media , 1980, The Annals of otology, rhinology & laryngology. Supplement.

[7]  R. Long,et al.  Cleft palate velopharyngeal musculature in a five-month-old infant: a three dimensional histological reconstruction. , 1980, The Cleft palate journal.

[8]  S. R. Rood,et al.  Anatomy of the eustachian tube and related structures in age-matched human fetuses with and without cleft palate. , 1976, Transactions. Section on Otolaryngology. American Academy of Ophthalmology and Otolaryngology.

[9]  D. R. Dickson.  Anatomy of the Normal and Cleft Palate Eustachian Tube , 1976, The Annals of otology, rhinology, and laryngology.

[10]  O. Kriens.  Anatomy of the velopharyngeal area in cleft palate. , 1975, Clinics in plastic surgery.

[11]  A. Preece.  A Manual for Histologic Technicians , 1972 .

[12]  J. Paradise,et al.  Roentgenographic evaluation of eustachian tube function in infants with cleft and normal palates. , 1972, The Cleft palate journal.

[13]  C. Bluestone.  Eustachian tube obstruction in the infant with cleft palate. , 1971, The Annals of otology, rhinology, and laryngology.

[14]  M. Ross.  Functional anatomy of the tensor palati. Its relevance in cleft palate surgery. , 1971, Archives of otolaryngology.

[15]  J. Paradise,et al.  The universality of otitis media in 50 infants with cleft palate. , 1969, Pediatrics.

[16]  I. Surina,et al.  Action potentials of levator and tensor muscles in patients with cleft palate. , 1969, Acta chirurgiae plasticae.

[17]  S. Stool,et al.  Unexpected ear disease in infants with cleft palate. , 1967, The Cleft palate journal.

[18]  J F A McMANUS,et al.  Histological and histochemical uses of periodic acid. , 1948, Stain technology.