论文信息 - Structure of actinomycin based on conformational studies.

Structure of actinomycin based on conformational studies.

ACTINOMYCIN (Fig. 1) inhibits DNA dependent RNA synthesis and binds specifically to DNA and double stranded poly-deoxyribonucleotides. The three-dimensional structure of actinomycin is therefore relevant to the molecular mechanism of its biological activity and the stereochemistry of replication.

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