Predicting Epileptic Seizures: Case Studies Harnessing Machine Learning

Epileptic seizure prediction is a critical patient-specific challenging task, relies on big data streams, and is essential for patient care. With the aid of recent advances, together with forthcoming technologies and powerful computing capabilities, smart healthcare attracts great attention in harnessing Intelligent Computing to yield seizure prediction and detection. However, it is unclear how even simple classification methods can be employed to carry out such challenging and mission-critical tasks. This paper investigates the performance impact of mainstream supervised Machine Learning techniques with different configurations in predicting epileptic seizures. A lab-premised testbed, along with neurophysiological data in dogs, enables the set of tests. Through analysis in the Area Under the ROC Curve (AUC) Key Performance Information (KPI), it was found that classification committees show improved performance capabilities than single classifiers. Overall, we believe this work represents a step towards making seizure prediction more accurate and widely available in different computational platforms.

[1]  Mark R. Bower,et al.  Microseizures and the spatiotemporal scales of human partial epilepsy. , 2010, Brain : a journal of neurology.

[2]  Nazim Agoulmine,et al.  A holistic approach to enable perceptive, instrumental and ubiquitous smart eHealth , 2015, 2015 Latin American Network Operations and Management Symposium (LANOMS).

[3]  Joel J. P. C. Rodrigues,et al.  Predicting hypertensive disorders in high-risk pregnancy using the random forest approach , 2017, 2017 IEEE International Conference on Communications (ICC).

[4]  Benjamin H. Brinkmann,et al.  Large-scale electrophysiology: Acquisition, compression, encryption, and storage of big data , 2009, Journal of Neuroscience Methods.

[5]  Érick O. Rodrigues,et al.  Combining Minkowski and Cheyshev: New distance proposal and survey of distance metrics using k-nearest neighbours classifier , 2018, Pattern Recognit. Lett..

[6]  Joel J. P. C. Rodrigues,et al.  Performance Evaluation of the Tree Augmented Naïve Bayes Classifier for Knowledge Discovery in Healthcare Databases , 2017 .

[7]  Brian Litt,et al.  Feasibility study of a caregiver seizure alert system in canine epilepsy , 2013, Epilepsy Research.

[8]  Leo Breiman,et al.  Bagging Predictors , 1996, Machine Learning.

[9]  O. Witte,et al.  Weather as a risk factor for epileptic seizures: A case‐crossover study , 2017, Epilepsia.

[10]  Joel J. P. C. Rodrigues,et al.  A Comprehensive Review on Smart Decision Support Systems for Health Care , 2019, IEEE Systems Journal.

[11]  Brian Litt,et al.  A multimodal platform for cloud-based collaborative research , 2013, 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER).

[12]  D. Kibler,et al.  Instance-based learning algorithms , 2004, Machine Learning.