Distribution of noradrenaline nerve terminals in cortical areas of the rat.

With the help of the histochemical fluorescence method for the demonstration of catecholamines it has been possible to establish that there exists a diffuse network of very fine, varicose noradrenaline nerve terminals in practically all parts of the cerebral cortex of the rat. The noradrenaline terminals probably mainly make axodendritic contacts preferentially in the terminal branches of the apical shaft, and are usually less frequent in the efferent layers of the cortex. These noradrenaline afferents probably originating from the lower brain stem may influence the activity of cortical areas of diverse functions, e.g. motor and sensory functions.

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