Non dermatophytic molds causing onychomycosis: a rising trend in North India

Onychomycosis refers to the invasion of the nail plate by a fungus. It is mainly caused by dermatophytes, but yeast and non-dermatophyte molds (NDM) have also been associated, leading to variable clinical presentations. 1 A number of factors contribute to the growing incidence of fungal nail infections, e.g. an increased aging population and an increasing number of immunocompromised state of patients. 2 Onychomycosis and other nail diseases can adversely affect the appearance of the entire nail unit, but most often it is regarded as a simple cosmetic problem of relatively minor importance that hardly seek any treatment in most of the cases. However, many patients with fungal nail infections experience serious physical, psychological, social, and occupational ill-effects. Onychomycosis affects approximately 5% of the population worldwide and represents 20-40% of the onychopathies and about 30% of cutaneous mycotic infections. 3 Various workers have reported the incidence to vary from 0.5 to 5% in the general population in India. 4,5 Although onychomycosis is rarely life threatening, its high incidence and prevalence and the associated morbidity makes it an important public health problem, thus it becomes important to look for the etiological agent and its treatment options. Although dermatophytes are still the major cause of superficial ABSTRACT

[1]  A. Lakshmanan,et al.  Epidemiological and clinical pattern of dermatomycoses in rural India , 2015, Indian journal of medical microbiology.

[2]  S. Khurshid,et al.  A study on clinico-mycological profile, aetiological agents and diagnosis of onychomycosis at a government medical college hospital in kashmir. , 2013, Journal of clinical and diagnostic research : JCDR.

[3]  S. Bassiri-Jahromi,et al.  NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN , 2010, Indian journal of dermatology.

[4]  S. A. Ghiasian,et al.  Onychomycosis in Iran: epidemiology, causative agents and clinical features. , 2010, Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology.

[5]  R. Pal,et al.  Clinico-etiologic correlates of onychomycosis in Sikkim. , 2009, Indian journal of pathology & microbiology.

[6]  S. Sarma,et al.  Epidemiologic and clinicomycologic profile of onychomycosis from north India , 2008, International journal of dermatology.

[7]  S. Teerthanath,et al.  Comparison of potassium hydroxide mount and mycological culture with histopathologic examination using periodic acid-Schiff staining of the nail clippings in the diagnosis of onychomycosis. , 2008, Indian journal of dermatology, venereology and leprology.

[8]  N. Das,et al.  A STUDY ON THE ETIOLOGICAL AGENT AND CLINICO-MYCOLOGICAL CORRELATION OF FINGERNAIL ONYCHOMYCOSIS IN EASTERN INDIA , 2008, Indian journal of dermatology.

[9]  R. Kaur,et al.  Onychomycosis--epidemiology, diagnosis and management. , 2008, Indian journal of medical microbiology.

[10]  M. Gupta,et al.  Onychomycosis: Clinico-mycologic study of 130 patients from Himachal Pradesh, India. , 2007, Indian journal of dermatology, venereology and leprology.

[11]  R. Kaur,et al.  A five-year survey of onychomycosis in New Delhi, India: Epidemiological and laboratory aspects , 2007 .

[12]  P. Veer,et al.  Study of onychomycosis: prevailing fungi and pattern of infection. , 2007, Indian journal of medical microbiology.

[13]  L. Naldi,et al.  Prevalence and Risk Factors for Superficial Fungal Infections among Italian Navy Cadets , 2004, Dermatology.

[14]  M. I. Álvarez,et al.  Onychomycosis in Cali, Colombia , 2004, Mycopathologia.

[15]  A. Vélez,et al.  Study of onychomycosis in Córdoba, Spain: Prevailing fungi and pattern of infection , 2004, Mycopathologia.

[16]  V. Ramesh Clinico-mycological evaluation of onychomycosis at Bangalore and Jorhat. , 2003, Indian journal of dermatology, venereology and leprology.

[17]  P. Roy,et al.  Clinico-mycological Profile of Superficial Mycosis in a Hospital in North-East India. , 2003, Medical journal, Armed Forces India.

[18]  R. Summerbell,et al.  The diagnosis of nondermatophyte mold onychomycosis , 2003, International journal of dermatology.

[19]  G. Rao,et al.  Onychomycosis: a significant medical problem. , 2002, Indian journal of dermatology, venereology and leprology.

[20]  Aditya K. Gupta,et al.  Candida infection of the nail: role of Candida as a primary or secondary pathogen , 1998, International journal of dermatology.

[21]  B. Elewski,et al.  Onychomycosis: Pathogenesis, Diagnosis, and Management , 1998, Clinical Microbiology Reviews.

[22]  R. Scher Onychomycosis: a significant medical disorder. , 1996, Journal of the American Academy of Dermatology.

[23]  K. Joshi,et al.  Dermatophytoses in a desert district of Western Rajasthan. , 1995, Indian journal of dermatology, venereology and leprology.

[24]  S. M. Singh,et al.  Non- dermatophytes as emerging opportunistic causal agents of superficial mycoses at Balaghat (M.P) , 1990 .

[25]  C. Sobbanadri,et al.  Clinical and Mycological Study of Superficial Fungal Infections at Government General Hospital, Guntur and their Response to Treatment with Hamycin, Dermostatin and Dermamycin. , 1970, Indian journal of dermatology and venereology.