Porphyromonas gingivalis, a periodontitis causing bacterium, induces memory impairment and age-dependent neuroinflammation in mice

[1]  Xuebo Liu,et al.  Sesamol supplementation prevents systemic inflammation‐induced memory impairment and amyloidogenesis via inhibition of nuclear factor kappaB , 2017, Molecular nutrition & food research.

[2]  Guohua Zhang,et al.  Effects of Ketamine on Levels of Inflammatory Cytokines IL-6, IL-1β, and TNF-α in the Hippocampus of Mice Following Acute or Chronic Administration , 2017, Front. Pharmacol..

[3]  Fuhua Yan,et al.  Manipulation of necroptosis by Porphyromonas gingivalis in periodontitis development. , 2016, Molecular immunology.

[4]  V. Perry,et al.  Periodontitis and Cognitive Decline in Alzheimer’s Disease , 2016, PloS one.

[5]  M. D. de Leon,et al.  Periodontal disease's contribution to Alzheimer's disease progression in Down syndrome , 2016, Alzheimer's & dementia.

[6]  J. Chan,et al.  Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus , 2015, Journal of Biomedical Science.

[7]  L. Kesavalu,et al.  Porphyromonas gingivalis Periodontal Infection and Its Putative Links with Alzheimer's Disease , 2015, Mediators of inflammation.

[8]  P. Lein,et al.  Using the Morris Water Maze to Assess Spatial Learning and Memory in Weanling Mice , 2015, PloS one.

[9]  Rupali Agnihotri,et al.  Alzheimer's disease and chronic periodontitis: Is there an association? , 2015, Geriatrics & gerontology international.

[10]  M. Leon,et al.  Periodontal disease associates with higher brain amyloid load in normal elderly , 2015, Neurobiology of Aging.

[11]  G. Hajishengallis,et al.  Periodontitis: from microbial immune subversion to systemic inflammation , 2014, Nature Reviews Immunology.

[12]  H. Nakanishi,et al.  Connection between periodontitis and Alzheimer's disease: possible roles of microglia and leptomeningeal cells. , 2014, Journal of pharmacological sciences.

[13]  G. Hu,et al.  Inhaled budesonide protects against chronic asthma-induced neuroinflammation in mouse brain , 2014, Journal of Neuroimmunology.

[14]  Aileen I. Pogue,et al.  Pathogenic microbes, the microbiome, and Alzheimer’s disease (AD) , 2014, Front. Aging Neurosci..

[15]  M. Kamal,et al.  How do periodontal infections affect the onset and progression of Alzheimer's disease? , 2014, CNS & neurological disorders drug targets.

[16]  M. Michikawa,et al.  Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice , 2013, Behavioural Brain Research.

[17]  H. Nakanishi,et al.  Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation , 2012, Neuroscience.

[18]  Urs Meyer,et al.  Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice , 2012, Journal of Neuroinflammation.

[19]  E. Marcantonio,et al.  The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β , 2012, Neurobiology of Aging.

[20]  N. Greig,et al.  Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease , 2012, Journal of Neuroinflammation.

[21]  Yongzhong Lin,et al.  Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation , 2012, Journal of Neuroinflammation.

[22]  Richard Reynolds,et al.  Innate Immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1) , 2012, Journal of Neuroinflammation.

[23]  M. Ganguli,et al.  Age, Alzheimer's disease, and the big picture , 2011, International Psychogeriatrics.

[24]  Karl Herrup,et al.  Reimagining Alzheimer's Disease—An Age-Based Hypothesis , 2010, The Journal of Neuroscience.

[25]  S. Resnick,et al.  Age, Alzheimer's disease and dementia in the Baltimore Longitudinal Study of Ageing. , 2010, Brain : a journal of neurology.

[26]  A. McAllister,et al.  Novel Roles for Immune Molecules in Neural Development: Implications for Neurodevelopmental Disorders , 2010, Front. Syn. Neurosci..

[27]  C. Holmes,et al.  Role of Infection in the Pathogenesis of Alzheimer’s Disease , 2009, CNS drugs.

[28]  M. Leon,et al.  TNF-α and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects , 2009, Journal of Neuroimmunology.

[29]  A. Anand,et al.  Bacopa monniera alleviates N ω-nitro-l-arginine-induced but not MK-801-induced amnesia: A mouse Morris water maze study , 2009, Neuroscience.

[30]  H. Nakanishi,et al.  Age-dependent responses of glial cells and leptomeninges during systemic inflammation , 2008, Neurobiology of Disease.

[31]  Lidia Glodzik-Sobanska,et al.  Inflammation and Alzheimer's disease: Possible role of periodontal diseases , 2008, Alzheimer's & Dementia.

[32]  R. Stewart,et al.  Dental Health and Cognitive Impairment in an English National Survey Population , 2007, Journal of the American Geriatrics Society.

[33]  F. Crews,et al.  Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration , 2007, Glia.

[34]  C. Vorhees,et al.  Morris water maze: procedures for assessing spatial and related forms of learning and memory , 2006, Nature Protocols.

[35]  M. O’Banion,et al.  Enhanced glial activation and expression of specific CNS inflammation-related molecules in aged versus young rats following cortical stab injury , 2001, Journal of Neuroimmunology.

[36]  R. D'Hooge,et al.  Applications of the Morris water maze in the study of learning and memory , 2001, Brain Research Reviews.

[37]  R. Morris Developments of a water-maze procedure for studying spatial learning in the rat , 1984, Journal of Neuroscience Methods.

[38]  Y. Yun,et al.  Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties. , 2013, The Journal of nutritional biochemistry.

[39]  I. Knuesel,et al.  Deciphering the mechanism underlying late-onset Alzheimer disease , 2013, Nature Reviews Neurology.

[40]  L. Kesavalu,et al.  Determining the presence of periodontopathic virulence factors in short-term postmortem Alzheimer's disease brain tissue. , 2013, Journal of Alzheimer's disease : JAD.

[41]  H. Praag,et al.  Tumor necrosis factor-alpha synthesis inhibitor 3,6' -dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease , 2012 .

[42]  E. L. Mortensen,et al.  Periodontal inflammation in relation to cognitive function in an older adult Danish population. , 2012, Journal of Alzheimer's disease : JAD.