Cryo-EM structures of human SPCA1a reveal the mechanism of Ca2+/Mn2+ transport into the Golgi apparatus
暂无分享,去创建一个
K. Inaba | M. Kikkawa | Michio Inoue | Yasukazu Daigaku | Satoshi Watanabe | Zhenghao Chen | Hironori Hashida | Hironori Hashida
[1] Y. Sugita,et al. Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. , 2022, Cell reports.
[2] K. Inaba,et al. Structural basis of the conformational and functional regulation of human SERCA2b, the ubiquitous endoplasmic reticulum calcium pump , 2022, BioEssays : news and reviews in molecular, cellular and developmental biology.
[3] Z. Deng,et al. Structure of the Wilson disease copper transporter ATP7B , 2022, Science advances.
[4] Helder Veras Ribeiro Filho,et al. pyKVFinder: an efficient and integrable Python package for biomolecular cavity detection and characterization in data science , 2021, BMC Bioinformatics.
[5] Sydney Drury,et al. Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2. , 2021, Molecular cell.
[6] G. Hummer,et al. Structural basis of polyamine transport by human ATP13A2 (PARK9). , 2021, Molecular cell.
[7] K. Inaba,et al. Cryo‐EM analysis provides new mechanistic insight into ATP binding to Ca2+‐ATPase SERCA2b , 2021, The EMBO journal.
[8] L. M. Espinoza-Fonseca,et al. Nothing Regular about the Regulins: Distinct Functional Properties of SERCA Transmembrane Peptide Regulatory Subunits , 2021, International journal of molecular sciences.
[9] Oriol Vinyals,et al. Highly accurate protein structure prediction with AlphaFold , 2021, Nature.
[10] David J. Fleet,et al. 3D Variability Analysis: Resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM. , 2021, Journal of structural biology.
[11] E. Pardon,et al. Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM , 2021, Nature Methods.
[12] C. Toyoshima,et al. What ATP binding does to the Ca2+ pump and how nonproductive phosphoryl transfer is prevented in the absence of Ca2+ , 2020, Proceedings of the National Academy of Sciences.
[13] L. M. Espinoza-Fonseca,et al. Linking Biochemical and Structural States of SERCA: Achievements, Challenges, and New Opportunities , 2020, International journal of molecular sciences.
[14] A. Hovnanian,et al. SPCA1 governs the stability of TMEM165 in Hailey-Hailey disease. , 2020, Biochimie.
[15] T. Nishizawa,et al. Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail , 2020, Science Advances.
[16] P. Alcón,et al. FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair , 2020, Nature Structural & Molecular Biology.
[17] David J. Fleet,et al. Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction , 2019, Nature Methods.
[18] Hua Yu,et al. The Ca2+ permeation mechanism of the ryanodine receptor revealed by a multi-site ion model , 2019, Nature Communications.
[19] P. Nissen,et al. Structure and Mechanism of P-Type ATPase Ion Pumps. , 2019, Annual review of biochemistry.
[20] Yoshiki Tanaka,et al. Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay. , 2019, Cell reports.
[21] M. García-García,et al. Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics , 2018, Development.
[22] Conor McMahon,et al. Yeast surface display platform for rapid discovery of conformationally selective nanobodies , 2018, Nature Structural & Molecular Biology.
[23] Conrad C. Huang,et al. UCSF ChimeraX: Meeting modern challenges in visualization and analysis , 2018, Protein science : a publication of the Protein Society.
[24] Christopher J. Williams,et al. MolProbity: More and better reference data for improved all‐atom structure validation , 2018, Protein science : a publication of the Protein Society.
[25] Daniel S. Terry,et al. Dynamics of P-type ATPase transport revealed by single-molecule FRET , 2017, Nature.
[26] T. Brummelkamp,et al. Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread. , 2017, Cell host & microbe.
[27] B. Roux,et al. Conformational Transitions and Alternating-Access Mechanism in the Sarcoplasmic Reticulum Calcium Pump. , 2017, Journal of molecular biology.
[28] David J. Fleet,et al. cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination , 2017, Nature Methods.
[29] M. Iino,et al. Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging. , 2016, Biophysical journal.
[30] A. Godzik,et al. Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination , 2016, Proceedings of the National Academy of Sciences.
[31] L. Federici,et al. ATP2C1 gene mutations in Hailey–Hailey disease and possible roles of SPCA1 isoforms in membrane trafficking , 2016, Cell Death and Disease.
[32] N. Grigorieff,et al. CTFFIND4: Fast and accurate defocus estimation from electron micrographs , 2015, bioRxiv.
[33] M. Michalak,et al. Ca(2+) homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling. , 2015, Biochemical and biophysical research communications.
[34] B. Habermann,et al. Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting , 2014, The Journal of cell biology.
[35] F. Wuytack,et al. High levels of Mn2+ inhibit secretory pathway Ca2+/Mn2+‐ATPase (SPCA) activity and cause Golgi fragmentation in neurons and glia , 2012, Journal of neurochemistry.
[36] T. Dresselaers,et al. Evaluation of manganese uptake and toxicity in mouse brain during continuous MnCl2 administration using osmotic pumps. , 2012, Contrast media & molecular imaging.
[37] E. Tajkhorshid,et al. Tracing cytoplasmic Ca(2+) ion and water access points in the Ca(2+)-ATPase. , 2012, Biophysical journal.
[38] T. Pozzan,et al. Ca(2+) signalling in the Golgi apparatus. , 2011, Cell calcium.
[39] Oliver Beckstein,et al. MDAnalysis: A toolkit for the analysis of molecular dynamics simulations , 2011, J. Comput. Chem..
[40] P. Nissen,et al. P-type ATPases. , 2011, Annual review of biophysics.
[41] Sabina Muend,et al. Vesicular distribution of Secretory Pathway Ca2+-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells , 2011, BioMetals.
[42] A. Linstedt,et al. Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity , 2010, Proceedings of the National Academy of Sciences.
[43] C. Toyoshima,et al. Structural aspects of ion pumping by Ca2+-ATPase of sarcoplasmic reticulum. , 2008, Archives of biochemistry and biophysics.
[44] Liang Tong,et al. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction , 2008, Nature Structural &Molecular Biology.
[45] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[46] R. Baker,et al. An efficient system for high‐level expression and easy purification of authentic recombinant proteins , 2004, Protein science : a publication of the Protein Society.
[47] C. Olanow,et al. Manganese‐Induced Parkinsonism and Parkinson's Disease , 2004, Annals of the New York Academy of Sciences.
[48] M. Nakasako,et al. Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution , 2000, Nature.
[49] T. Mauro,et al. Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease , 2000, Nature Genetics.
[50] R. Kaufman,et al. Depletion of manganese within the secretory pathway inhibits O-linked glycosylation in mammalian cells. , 1994, Biochemistry.
[51] K. Simons,et al. The trans Golgi network: sorting at the exit site of the Golgi complex. , 1986, Science.
[52] R. Albers. Biochemical aspects of active transport. , 1967, Annual review of biochemistry.