The genetic predisposition to adverse outcome after trauma.
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[1] J. Hazelzet,et al. Plasminogen activator inhibitor type 1 gene polymorphism and sepsis. , 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[2] M. Newman,et al. APOE polymorphism is associated with risk of severe sepsis in surgical patients* , 2005, Critical care medicine.
[3] D. Christiani,et al. −308GA and TNFB polymorphisms in acute respiratory distress syndrome , 2005, European Respiratory Journal.
[4] R. Wunderink,et al. Genetic susceptibility to pneumonia. , 2005, Clinics in chest medicine.
[5] Jacob E. Wang. Can single nucleotide polymorphisms in innate immune receptors predict development of septic complications in intensive care unit patients? , 2005, Critical Care Medicine.
[6] K. Walley,et al. Polymorphisms in CD14, mannose-binding lectin, and Toll-like receptor-2 are associated with increased prevalence of infection in critically ill adults* , 2005, Critical care medicine.
[7] A. Medford,et al. Vascular endothelial growth factor gene polymorphism and acute respiratory distress syndrome , 2005, Thorax.
[8] K. Walley,et al. The association of interleukin 6 haplotype clades with mortality in critically ill adults. , 2005, Archives of internal medicine.
[9] A. Gordon,et al. TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study , 2004, Genes and Immunity.
[10] J. Hunt,et al. TLR4 and TNF-α polymorphisms are associated with an increased risk for severe sepsis following burn injury , 2004, Journal of Medical Genetics.
[11] G. O’Keefe,et al. Genetic determinants of the inflammatory response , 2004, Current opinion in critical care.
[12] A. Ekkernkamp,et al. ASSOCIATION OF INTERLEUKIN-10 PROMOTER POLYMORPHISM WITH THE INCIDENCE OF MULTIPLE ORGAN DYSFUNCTION FOLLOWING MAJOR TRAUMA: RESULTS OF A PROSPECTIVE PILOT STUDY , 2004, Shock.
[13] P. Zabel,et al. Pneumococcal septic shock is associated with the interleukin-10-1082 gene promoter polymorphism. , 2003, American journal of respiratory and critical care medicine.
[14] N. Stassen,et al. IL-18 promoter polymorphisms correlate with the development of post-injury sepsis. , 2003, Surgery.
[15] P. Giannoudis,et al. Current concepts of the inflammatory response after major trauma: an update. , 2003, Injury.
[16] G. O’Keefe,et al. Characterization of a single nucleotide polymorphism in the lipopolysaccharide binding protein and its association with sepsis. , 2003, American journal of respiratory and critical care medicine.
[17] J. Verhoef,et al. Lipoprotein metabolism in patients with severe sepsis , 2003, Critical care medicine.
[18] B. Dahlbäck,et al. Activated protein C resistance (FV(Leiden)) and thrombosis: factor V mutations causing hypercoagulable states. , 2003, Hematology/oncology clinics of North America.
[19] N. Webster,et al. Influence of interleukin-10 polymorphisms on interleukin-10 expression and survival in critically ill patients* , 2003, Critical care medicine.
[20] Jonathan Cohen. The immunopathogenesis of sepsis , 2002, Nature.
[21] F. Schade,et al. Tumor Necrosis Factor Gene Polymorphisms, Leukocyte Function, and Sepsis Susceptibility in Blunt Trauma Patients , 2002, Clinical and Vaccine Immunology.
[22] S. Humphries,et al. Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. , 2002, American journal of respiratory and critical care medicine.
[23] N. Stassen,et al. Interferon-γ gene polymorphisms and the development of sepsis in patients with trauma * , 2002 .
[24] S. Dzik. Early goal-directed therapy in the treatment of severe sepsis and septic shock , 2002 .
[25] G. O’Keefe,et al. The G-->A single nucleotide polymorphism at the -308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis after trauma. , 2002, The Journal of trauma.
[26] Alastair Forbes,et al. The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. , 2002, Gastroenterology.
[27] E. Lonn,et al. The T-786→C Mutation in Endothelial Nitric Oxide Synthase Is Associated With Hypertension , 2002, Hypertension.
[28] K. Sullivan,et al. An osteopontin (SPP1) polymorphism is associated with systemic lupus erythematosus , 2002, Human mutation.
[29] Wei Huang,et al. Sequence variations in the mu‐opioid receptor gene (OPRM1) associated with human addiction to heroin , 2002, Human mutation.
[30] S. DeKosky,et al. Genetic variation in α1-antichymotrypsin and its association with Alzheimer’s disease , 2002, Human Genetics.
[31] R. Cantor,et al. Tumor necrosis factor gene polymorphisms and the variable presentation and outcome of community-acquired pneumonia. , 2002, Chest.
[32] W. Thomson,et al. Intercellular adhesion molecule-1 gene polymorphisms in isolated polymyalgia rheumatica. , 2002, The Journal of rheumatology.
[33] C. Frevert,et al. High and low inflammatory response phenotypes in 101 normal human subjects. , 2002, Chest.
[34] S. Nadel. Helping to understand studies examining genetic susceptibility to sepsis , 2002, Clinical and experimental immunology.
[35] F. Tsai,et al. Relation of vitamin D receptor FokI start codon polymorphism to bone mineral density and occurrence of osteoporosis in postmenopausal women in Taiwan , 2002, Acta obstetricia et gynecologica Scandinavica.
[36] G. Assmann,et al. Effect of the interleukin-6 promoter polymorphism (−174 G/C) on the incidence and outcome of sepsis , 2002, Critical care medicine.
[37] Jeffrey I. Weitz,et al. Characterization of a Mouse Model for Thrombomodulin Deficiency , 2001, Arteriosclerosis, thrombosis, and vascular biology.
[38] P. Barie,et al. Relationship of hypolipidemia to cytokine concentrations and outcomes in critically ill surgical patients , 2001, Critical care medicine.
[39] B. Beutler,et al. The sole gateway to endotoxin response: how LPS was identified as Tlr4, and its role in innate immunity. , 2001, Drug metabolism and disposition: the biological fate of chemicals.
[40] T. V. van Berkel,et al. Apolipoprotein E Protects Against Bacterial Lipopolysaccharide-induced Lethality , 2001, The Journal of Biological Chemistry.
[41] G. Rothe,et al. Gene variants of the bactericidal/permeability increasing protein and lipopolysaccharide binding protein in sepsis patients: Gender-specific genetic predisposition to sepsis , 2001, Critical care medicine.
[42] D. Laskowitz,et al. Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response , 2001, Journal of Neuroimmunology.
[43] F. Stüber,et al. Gender differences in sepsis: genetically determined? , 2000, Shock.
[44] D. Arveiler,et al. Polymorphisms in the 5' regulatory region of the tissue factor gene and the risk of myocardial infarction and venous thromboembolism: the ECTIM and PATHROS studies. Etude Cas-Témoins de l'Infarctus du Myocarde. Paris Thrombosis case-control Study. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[45] W. Ricart,et al. Interleukin-6 gene polymorphism and insulin sensitivity. , 2000, Diabetes.
[46] S. D'alfonso,et al. New polymorphisms in the IL-10 promoter region , 2000, Genes and Immunity.
[47] F. Stüber,et al. Relation of a TNF gene polymorphism to severe sepsis in trauma patients. , 1999, Annals of surgery.
[48] D. Purdie,et al. Interleukin‐10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa , 1999, Hepatology.
[49] A. Hoeft,et al. Analysis of two human leukocyte antigen-linked polymorphic heat shock protein 70 genes in patients with severe sepsis. , 1999, Critical care medicine.
[50] P. Woo,et al. Polymorphic haplotypes of the interleukin-10 5' flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. , 1999, Arthritis and rheumatism.
[51] P. Holt,et al. A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. , 1999, American journal of respiratory cell and molecular biology.
[52] M. Netea,et al. Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection. , 1999, Journal of lipid research.
[53] F. Schade,et al. Relation of ex vivo stimulated blood cytokine synthesis to post-traumatic sepsis. , 1999, Cytokine.
[54] K. Werdan,et al. ASSOCIATION OF SERUM TUMOR NECROSIS FACTOR LEVELS WITH DECREASE OF CHOLESTEROL DURING SEPTIC SHOCK , 1998, Shock.
[55] A. Daugherty,et al. Apolipoprotein E-deficient mice have impaired innate immune responses to Listeria monocytogenes in vivo. , 1998, Journal of lipid research.
[56] R. Westendorp,et al. Interleukin 10 secretion in relation to human IL-10 locus haplotypes. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[57] P. Giannoudis,et al. Trauma and the immune response , 1998, Journal of the Royal Society of Medicine.
[58] R. Dickson,et al. Stimulation of inflammatory markers after blunt trauma , 1998, The British journal of surgery.
[59] G. Regel,et al. Cytokines and adhesion molecules in elective and accidental trauma-related ischemia/reperfusion. , 1998, The Journal of trauma.
[60] M. Lazarus,et al. An investigation of polymorphism in the interleukin-10 gene promoter. , 1997, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.
[61] M. Newport,et al. A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. , 1996, The New England journal of medicine.
[62] M. Newport,et al. Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guérin infection. , 1996, The New England journal of medicine.
[63] P. Reitsma,et al. Five novel intragenic dimorphisms in the human interleukin-1 genes combine to high informativity. , 1996, Cytokine.
[64] J. Carcillo,et al. Inflammatory cytokine and nitric oxide responses in pediatric sepsis and organ failure. , 1996, Critical care medicine.
[65] G. Siest,et al. Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors. , 1996, Journal of lipid research.
[66] S. Anttila,et al. Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility--a review. , 1995, Gene.
[67] P. Guillou,et al. Biological variation in the development of sepsis after surgery or trauma , 1993, The Lancet.
[68] F. Pociot,et al. An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles , 1993, The Journal of experimental medicine.
[69] P. Jeggo,et al. The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14–q21, in the region of the IL-1α and IL-1β loci , 1992 .
[70] J. E. Carceller. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis , 1992, Critical care medicine.
[71] F. Pociot,et al. A Taql polymorphism in the human interleukin‐1β (IL‐1β) gene correlates with IL‐1β secretion in vitro , 1992 .
[72] W. Knaus,et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. , 1992, Chest.
[73] U. Spengler,et al. Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF- beta production , 1991, The Journal of experimental medicine.
[74] R. Ulevitch,et al. Structure and function of lipopolysaccharide binding protein. , 1990, Science.
[75] A. Bowcock,et al. Rapid detection and sequencing of alleles in the 3' flanking region of the interleukin-6 gene. , 1989, Nucleic acids research.
[76] E. Abraham. Host defense abnormalities after hemorrhage, trauma, and burns. , 1989, Critical care medicine.
[77] T. Taniguchi,et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin , 1986, Nature.
[78] M. Yamada,et al. Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor. , 1985, Nucleic acids research.
[79] L. J. Eldik,et al. A dual role for apolipoprotein E in neuroinflammation , 2007, Journal of Molecular Neuroscience.
[80] D. Dries. Genetic predisposition for a compromised immune system after multiple trauma , 2007 .
[81] D. Christiani,et al. Polymorphism in the surfactant protein-B gene, gender, and the risk of direct pulmonary injury and ARDS. , 2004, Chest.
[82] David T. Huang,et al. Early goal-directed therapy. , 2004, Critical care medicine.
[83] G. Gallagher,et al. A polymorphic dinucleotide repeat in the human IL-10 promoter , 2004, Immunogenetics.
[84] D. Kunz,et al. Linkage disequilibrium between tumor necrosis factor (TNF)-alpha-308 G/A promoter and TNF-beta NcoI polymorphisms: Association with TNF-alpha response of granulocytes to endotoxin stimulation. , 2003, Critical care medicine.
[85] N. Stassen,et al. Interferon-gamma gene polymorphisms and the development of sepsis in patients with trauma. , 2002, Surgery.
[86] J. Buxbaum,et al. Association between a GABRB3 polymorphism and autism , 2002, Molecular Psychiatry.
[87] O. Migita,et al. An association between a missense polymorphism in the close homologue of L1 (CHL1, CALL) gene and schizophrenia , 2002, Molecular Psychiatry.
[88] S. DeKosky,et al. Genetic variation in alpha(1)-antichymotrypsin and its association with Alzheimer's disease. , 2002, Human genetics.
[89] Dechang Chen,et al. [Genomic polymorphism within interleukin-1 family cytokines influences the outcome of septic patients]. , 2002, Zhonghua yi xue za zhi.
[90] J. Helterbrand,et al. Efficacy and safety of recombinant human activated protein C for severe sepsis , 2003 .
[91] S. D'alfonso,et al. Systemic lupus erythematosus candidate genes in the Italian population: evidence for a significant association with interleukin-10. , 2000, Arthritis and rheumatism.
[92] I. Udalova,et al. -308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter. , 1995, Journal of inflammation.
[93] F. Pociot,et al. A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro. , 1992, European journal of clinical investigation.
[94] L. Shingarova,et al. Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome. , 1986, Cold Spring Harbor symposia on quantitative biology.
[95] PHILIP,et al. The Journal of Bone and Joint Surgery. , 1950, Annals of the Royal College of Surgeons of England.