Optimising experimental research in respiratory diseases: an ERS statement
暂无分享,去创建一个
G. Joos | W. Kuebler | L. Richeldi | A. Fabre | O. Eickelberg | A. Guenther | N. Frossard | E. White | G. Jenkins | M. Kolb | M. Inman | S. Uhlig | B. Crestani | M. Stampfli | A. Magnan | T. Maes | P. Reinhold | U. Maus | C. Guignabert | W. Shi | M. Witzenrath | P. Bellaye | B. Maître | H. Fehrenbach | P. Bonniaud | J. Vernooy
[1] B. Canning,et al. Evidence for autocrine and paracrine regulation of allergen‐induced mast cell mediator release in the guinea pig airways , 2017, European journal of pharmacology.
[2] Matthias Stefan Eggel,et al. The logic, methodological and practical limitations in the current benefit concept in the harm-benefit-analysis : an investigation in the context of the EU directive 2010/63 on the protection of animals used for scientific purposes , 2018 .
[3] P. Giavina-Bianchi,et al. Animal models of asthma: utility and limitations , 2017, Journal of asthma and allergy.
[4] Nuno Bandeira,et al. Three-Dimensional Microbiome and Metabolome Cartography of a Diseased Human Lung. , 2017, Cell host & microbe.
[5] J. Laffey,et al. Fifty Years of Research in ARDS., Insight into Acute Respiratory Distress Syndrome. From Models to Patients , 2017, American journal of respiratory and critical care medicine.
[6] C. Korch,et al. Widespread Use of Misidentified Cell Line KB (HeLa): Incorrect Attribution and Its Impact Revealed through Mining the Scientific Literature. , 2017, Cancer research.
[7] R. Lutter,et al. An early innate response underlies severe influenza‐induced exacerbations of asthma in a novel steroid‐insensitive and anti‐IL‐5‐responsive mouse model , 2017, Allergy.
[8] R. Chambers,et al. An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis , 2017, American journal of respiratory cell and molecular biology.
[9] R. Bonomo,et al. In Vitro Discordance with In Vivo Activity: Humanized Exposures of Ceftazidime-Avibactam, Aztreonam, and Tigecycline Alone and in Combination against New Delhi Metallo-β-Lactamase-Producing Klebsiella pneumoniae in a Murine Lung Infection Model , 2017, Antimicrobial Agents and Chemotherapy.
[10] Zhiguo Zhao,et al. Clinical Predictors of Hospital Mortality Differ Between Direct and Indirect ARDS , 2017, Chest.
[11] I. Pavord,et al. Meta‐analysis of asthma‐related hospitalization in mepolizumab studies of severe eosinophilic asthma , 2017, The Journal of allergy and clinical immunology.
[12] L. Touqui,et al. Bacteria-driven peribronchial lymphoid neogenesis in bronchiectasis and cystic fibrosis , 2017, European Respiratory Journal.
[13] Neil J Kelly,et al. Development of a Mouse Model of Metabolic Syndrome, Pulmonary Hypertension, and Heart Failure with Preserved Ejection Fraction , 2017, American journal of respiratory cell and molecular biology.
[14] M. Humbert,et al. Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension , 2017, American journal of respiratory and critical care medicine.
[15] Laffey Jg,et al. Fifty Years of Research in ARDS. Insight into ARDS - From Models to Patients. , 2017 .
[16] I. Adcock,et al. MicroRNA‐21 drives severe, steroid‐insensitive experimental asthma by amplifying phosphoinositide 3‐kinase–mediated suppression of histone deacetylase 2 , 2017, The Journal of allergy and clinical immunology.
[17] I. Adcock,et al. Animal models of COPD: What do they tell us? , 2017, Respirology.
[18] G. Joos,et al. Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses , 2016, The Journal of allergy and clinical immunology.
[19] A. Malhotra,et al. Treatment of ARDS With Prone Positioning. , 2017, Chest.
[20] Chronic Obstructive Pulmonary Disease in Non-Smokers. , 2017, Archivos de bronconeumologia.
[21] A. Lawrie,et al. Targeting Vascular Remodeling to Treat Pulmonary Arterial Hypertension. , 2017, Trends in molecular medicine.
[22] Ewald R. Weibel,et al. Lung morphometry: the link between structure and function , 2017, Cell and Tissue Research.
[23] B. Stripp,et al. Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. , 2016, JCI insight.
[24] J. Blalock,et al. A ferret model of COPD-related chronic bronchitis. , 2016, JCI insight.
[25] M. Humbert,et al. Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension. , 2016, The Journal of clinical investigation.
[26] Elise C. Wilcox,et al. Comparative biology of decellularized lung matrix: Implications of species mismatch in regenerative medicine. , 2016, Biomaterials.
[27] G. K. Khurana Hershey,et al. A combination of dexamethasone and anti-IL-17A treatment can alleviate diesel exhaust particle-induced steroid insensitive asthma. , 2016, The Journal of allergy and clinical immunology.
[28] I. Petrache,et al. Alpha-1 Antitrypsin Investigations Using Animal Models of Emphysema. , 2016, Annals of the American Thoracic Society.
[29] J. Smith,et al. Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate , 2016, The Journal of allergy and clinical immunology.
[30] J. Wharton,et al. Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2&agr; , 2016, Circulation.
[31] M. Peitsch,et al. The Apoe−/− mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction , 2016, Journal of Translational Medicine.
[32] Robert Paine,et al. Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. , 2016, The New England journal of medicine.
[33] J. Dötsch,et al. Early-onset obesity dysregulates pulmonary adipocytokine/insulin signaling and induces asthma-like disease in mice , 2016, Scientific Reports.
[34] Miranda Kirby,et al. Sex Differences in Airway Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease. , 2016, American journal of respiratory and critical care medicine.
[35] Anders Larsson,et al. Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. , 2016, JAMA.
[36] I. Mahmutovic Persson,et al. Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation , 2016, Journal of Translational Medicine.
[37] R. Gosens,et al. Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma , 2016, Respiratory Research.
[38] M. Marenzana,et al. Refine, reduce, replace: Imaging of fibrosis and arthritis in animal models. , 2015, Best practice & research. Clinical rheumatology.
[39] Shinu Abraham,et al. Lung-function trajectories leading to chronic obstructive pulmonary disease , 2015 .
[40] M. Beers,et al. Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease. , 2015, American journal of physiology. Lung cellular and molecular physiology.
[41] H. Hammad,et al. Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells , 2015, Science.
[42] Host genetic diversity influences the severity of Pseudomonas aeruginosa pneumonia in the Collaborative Cross mice , 2015, BMC Genetics.
[43] B. Bolon,et al. Mouse Models of Acute Respiratory Distress Syndrome , 2015, Toxicologic pathology.
[44] M. Lindner,et al. Multidimensional immunolabeling and 4D time-lapse imaging of vital ex vivo lung tissue. , 2015, American journal of physiology. Lung cellular and molecular physiology.
[45] B. Lambrecht,et al. Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma , 2015, PloS one.
[46] K. Snibson,et al. Structural and functional correlations in a large animal model of bleomycin-induced pulmonary fibrosis , 2015, BMC Pulmonary Medicine.
[47] K. Schughart,et al. Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background , 2015, Journal of Virology.
[48] S. Bozinovski,et al. Preclinical murine models of Chronic Obstructive Pulmonary Disease. , 2015, European journal of pharmacology.
[49] Sabrina Z. Wang,et al. Upregulation of canonical transient receptor potential channel in the pulmonary arterial smooth muscle of a chronic thromboembolic pulmonary hypertension rat model , 2015, Hypertension Research.
[50] A. Magnan,et al. Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite-induced allergic asthma model. , 2015, The Journal of allergy and clinical immunology.
[51] J. Tiedje,et al. Alterations of the Murine Gut Microbiome with Age and Allergic Airway Disease , 2015, Journal of immunology research.
[52] W. Seeger,et al. Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin , 2015, Thorax.
[53] Correction: Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key Sugar in Colonisation and Infection , 2015, PloS one.
[54] C. Orihuela,et al. Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling. , 2015, Journal of visualized experiments : JoVE.
[55] A. Neves,et al. Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key Sugar in Colonisation and Infection , 2015, PloS one.
[56] Dirkje S Postma,et al. Risk factors and early origins of chronic obstructive pulmonary disease , 2015, The Lancet.
[57] A. Gruber,et al. Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia. , 2015, The Journal of antimicrobial chemotherapy.
[58] I. Adcock,et al. Translational models of lung disease. , 2015, Clinical science.
[59] M. Humbert,et al. New molecular targets of pulmonary vascular remodeling in pulmonary arterial hypertension: importance of endothelial communication. , 2015, Chest.
[60] R. Kaarteenaho,et al. Pharmacological treatment of idiopathic pulmonary fibrosis – preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine , 2015, European clinical respiratory journal.
[61] A. Azuma,et al. A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis , 2015 .
[62] Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis. , 2015, The New England journal of medicine.
[63] R. Schermuly,et al. [Relevant issues in the pathology and pathobiology of pulmonary hypertension]. , 2014, Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
[64] G. Rossi,et al. Host Genetic Background Influences the Response to the Opportunistic Pseudomonas aeruginosa Infection Altering Cell-Mediated Immunity and Bacterial Replication , 2014, PloS one.
[65] T. Welte,et al. Basophil expansion protects against invasive pneumococcal disease in mice. , 2014, The Journal of infectious diseases.
[66] A. Gruber,et al. Miniaturized bronchoscopy enables unilateral investigation, application, and sampling in mice. , 2014, American journal of respiratory cell and molecular biology.
[67] K. Dhaliwal,et al. Chronic pleuropulmonary fibrosis and elastosis of aged donkeys: similarities to human pleuroparenchymal fibroelastosis. , 2014, Chest.
[68] L. Moldawer,et al. A Better Understanding of Why Murine Models of Trauma Do Not Recapitulate the Human Syndrome* , 2014, Critical care medicine.
[69] W. Kuebler,et al. Differential Regulation of Lung Endothelial Permeability in Vitro and in Situ , 2014, Cellular Physiology and Biochemistry.
[70] R. Sussman,et al. A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis. , 2014, The New England journal of medicine.
[71] Nathan Foje,et al. Preclinical anatomical, molecular, and functional imaging of the lung with multiple modalities. , 2014, American journal of physiology. Lung cellular and molecular physiology.
[72] Martin J. Aryee,et al. Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing , 2014, Nature Biotechnology.
[73] A. Gruber,et al. Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin , 2014, Critical Care.
[74] Jeffry D. Sander,et al. CRISPR-Cas systems for editing, regulating and targeting genomes , 2014, Nature Biotechnology.
[75] J. Ioannidis,et al. Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses , 2014, Intensive Care Medicine.
[76] M. Humbert,et al. Immune Dysregulation and Endothelial Dysfunction in Pulmonary Arterial Hypertension: A Complex Interplay , 2014, Circulation.
[77] K. Le Boedec,et al. A case of atypical diffuse feline fibrotic lung disease , 2014, Journal of feline medicine and surgery.
[78] A. Lawrie. A Report on the Use of Animal Models and Phenotyping Methods in Pulmonary Hypertension Research , 2014, Pulmonary circulation.
[79] G. Viegi,et al. The aetiology and antibiotic management of community-acquired pneumonia in adults in Europe: a literature review , 2014, European Journal of Clinical Microbiology & Infectious Diseases.
[80] J. Arnhold,et al. Differences in innate immune response between man and mouse. , 2014, Critical reviews in immunology.
[81] M. Rajamäki,et al. Idiopathic pulmonary fibrosis in West Highland white terriers. , 2014, The Veterinary clinics of North America. Small animal practice.
[82] K. Brown,et al. An official American thoracic society workshop report: comparative pathobiology of fibrosing lung disorders in humans and domestic animals. , 2013, Annals of the American Thoracic Society.
[83] E. Bleecker,et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma , 2013, European Respiratory Journal.
[84] D. Warburton,et al. Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer , 2013, BMC Biology.
[85] E. R. Lafontaine,et al. Use of a Safe, Reproducible, and Rapid Aerosol Delivery Method to Study Infection by Burkholderia pseudomallei and Burkholderia mallei in Mice , 2013, PloS one.
[86] S. Cirera,et al. Functional Characterization of a Porcine Emphysema Model , 2013, Lung.
[87] David A. Scott,et al. Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity , 2013, Cell.
[88] J. Axon,et al. Equine multinodular pulmonary fibrosis in three horses in Australia. , 2013, Australian veterinary journal.
[89] P. Foster,et al. Murine models of infectious exacerbations of airway inflammation. , 2013, Current opinion in pharmacology.
[90] Laimute Taraseviciene-Stewart,et al. Tobacco smoke induced COPD/emphysema in the animal model—are we all on the same page? , 2013, Front. Physiol..
[91] R. Hoven,et al. Equine multinodular pulmonary fibrosis (EMPF): Five case reports. , 2013, Acta veterinaria Hungarica.
[92] O. Distler,et al. The Fra-2 transgenic mouse model of systemic sclerosis. , 2013, Vascular pharmacology.
[93] Muriel Hachet-Haas,et al. An Antedrug of the CXCL12 Neutraligand Blocks Experimental Allergic Asthma without Systemic Effect in Mice , 2013, The Journal of Biological Chemistry.
[94] E. Fadel,et al. Chronic thromboembolic pulmonary hypertension: animal models , 2013, European Respiratory Journal.
[95] Horst Olschewski,et al. Updated clinical classification of pulmonary hypertension. , 2009, Journal of the American College of Cardiology.
[96] F. Martinez,et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. , 2007, American journal of respiratory and critical care medicine.
[97] C. Bauer,et al. The influence of cigarette smoking on viral infections: translating bench science to impact COPD pathogenesis and acute exacerbations of COPD clinically. , 2013, Chest.
[98] G. Joos,et al. Targeting interleukin-4 in asthma: lost in translation? , 2012, American journal of respiratory cell and molecular biology.
[99] S. Reynolds,et al. Roles for β-catenin and doxycycline in the regulation of respiratory epithelial cell frequency and function. , 2012, American journal of respiratory cell and molecular biology.
[100] E. Rawlins,et al. The a"MAZE"ing world of lung-specific transgenic mice. , 2012, American journal of respiratory cell and molecular biology.
[101] N. Franco,et al. Animal Welfare in Studies on Murine Tuberculosis: Assessing Progress over a 12-Year Period and the Need for Further Improvement , 2012, PloS one.
[102] T. Welte,et al. TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice , 2012, The Journal of experimental medicine.
[103] H. Hammad,et al. Short cigarette smoke exposure facilitates sensitisation and asthma development in mice , 2012, European Respiratory Journal.
[104] M. Stämpfli,et al. Cigarette smoke-induced inflammation and respiratory host defense: Insights from animal models. , 2012, Pulmonary pharmacology & therapeutics.
[105] B. Stripp,et al. Building and maintaining the epithelium of the lung. , 2012, The Journal of clinical investigation.
[106] Roger Schibli,et al. Can animal data predict human outcome? Problems and pitfalls of translational animal research , 2012, European Journal of Nuclear Medicine and Molecular Imaging.
[107] Arthur S Slutsky,et al. Acute Respiratory Distress Syndrome The Berlin Definition , 2012 .
[108] S. Uhlig,et al. Models and mechanisms of acute lung injury caused by direct insults. , 2012, European journal of cell biology.
[109] P. Chanez,et al. An ex vivo model of severe asthma using reconstituted human bronchial epithelium. , 2012, The Journal of allergy and clinical immunology.
[110] S. Wenzel. Asthma phenotypes: the evolution from clinical to molecular approaches , 2012, Nature Medicine.
[111] J. Kriegsmann,et al. Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis , 2012, Annals of the rheumatic diseases.
[112] Joseph B Zwischenberger,et al. Large-animal models of acute respiratory distress syndrome. , 2012, The Annals of thoracic surgery.
[113] T. Bonfield. In Vivo Models of Lung Disease , 2012 .
[114] E. Irusen. Lung Diseases - Selected State of the Art Reviews , 2012 .
[115] A. K. Hansen,et al. Time to include the gut microbiota in the hygienic standardisation of laboratory rodents. , 2012, Comparative immunology, microbiology and infectious diseases.
[116] A. Pawłowski,et al. Failure To Recruit Anti-Inflammatory CD103+ Dendritic Cells and a Diminished CD4+ Foxp3+ Regulatory T Cell Pool in Mice That Display Excessive Lung Inflammation and Increased Susceptibility to Mycobacterium tuberculosis , 2012, Infection and Immunity.
[117] Sucheol Gil,et al. Doxycycline impairs neutrophil migration to the airspaces of the lung in mice exposed to intratracheal lipopolysaccharide , 2012, Journal of Inflammation.
[118] M. Takata,et al. Resolution of acute lung injury and inflammation: a translational mouse model , 2011, European Respiratory Journal.
[119] F. Collins,et al. Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. , 2011, American journal of respiratory cell and molecular biology.
[120] C. Reinero. Advances in the understanding of pathogenesis, and diagnostics and therapeutics for feline allergic asthma. , 2011, Veterinary journal.
[121] D. Trist,et al. Scientific process, pharmacology and drug discovery. , 2011, Current opinion in pharmacology.
[122] L. Edwards,et al. Changes in forced expiratory volume in 1 second over time in COPD. , 2011, The New England journal of medicine.
[123] J. Engelhardt,et al. New animal models of cystic fibrosis: what are they teaching us? , 2011, Current opinion in pulmonary medicine.
[124] A. Akram,et al. Epidemiology, antibiotic therapy, and clinical outcomes in health care-associated pneumonia: a UK cohort study. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[125] K. Bruse,et al. Animal models of pulmonary hypertension , 2011 .
[126] J. Müller‐Quernheim,et al. MMPs are regulatory enzymes in pathways of inflammatory disorders, tissue injury, malignancies and remodelling of the lung , 2011, European Respiratory Journal.
[127] D. Sin,et al. Everything prevents emphysema: are animal models of cigarette smoke-induced chronic obstructive pulmonary disease any use? , 2011, American journal of respiratory cell and molecular biology.
[128] M. Wadman. Animal rights: Chimpanzee research on trial , 2011, Nature.
[129] M. Rajamäki,et al. Clinical, bronchoscopic, histopathologic, diagnostic imaging, and arterial oxygenation findings in West Highland White Terriers with idiopathic pulmonary fibrosis. , 2011, Journal of veterinary internal medicine.
[130] Christopher S. Stevenson,et al. Moving towards a new generation of animal models for asthma and COPD with improved clinical relevance. , 2011, Pharmacology & therapeutics.
[131] M. Kling. A Review of Respiratory System Anatomy, Physiology, and Disease in the Mouse, Rat, Hamster, and Gerbil , 2011, Veterinary Clinics of North America: Exotic Animal Practice.
[132] Arthur S Slutsky,et al. An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. , 2011, American journal of respiratory cell and molecular biology.
[133] Liqun Luo,et al. Site-specific integrase-mediated transgenesis in mice via pronuclear injection , 2011, Proceedings of the National Academy of Sciences.
[134] S. Richter,et al. The ΔF508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis–Like Disease in Pigs , 2011, Science Translational Medicine.
[135] Brian J. Bennett,et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease , 2011, Nature.
[136] Adnan Custovic,et al. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. , 2011, The Journal of allergy and clinical immunology.
[137] Dan Xu,et al. Doxycycline attenuates acrolein-induced mucin production, in part by inhibiting MMP-9. , 2011, European journal of pharmacology.
[138] Kelly Bérubé,et al. Human primary bronchial lung cell constructs: the new respiratory models. , 2010, Toxicology.
[139] W. Kuebler,et al. Mast cells promote lung vascular remodelling in pulmonary hypertension , 2010, European Respiratory Journal.
[140] D. Nicolau,et al. Comparative Efficacies of Human Simulated Exposures of Telavancin and Vancomycin against Methicillin-Resistant Staphylococcus aureus with a Range of Vancomycin MICs in a Murine Pneumonia Model , 2010, Antimicrobial Agents and Chemotherapy.
[141] David K Meyerholz,et al. Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis. , 2010, The Journal of clinical investigation.
[142] T. Welte,et al. Clinical and economic burden of community-acquired pneumonia among adults in Europe , 2010, Thorax.
[143] N. Suttorp,et al. RNAi-mediated suppression of constitutive pulmonary gene expression by small interfering RNA in mice. , 2010, Pulmonary pharmacology & therapeutics.
[144] Geoffrey McLennan,et al. Lung structure phenotype variation in inbred mouse strains revealed through in vivo micro-CT imaging. , 2010, Journal of applied physiology.
[145] C. Ruppert,et al. Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia. , 2010, American journal of respiratory and critical care medicine.
[146] I. Cuthill,et al. Reporting : The ARRIVE Guidelines for Reporting Animal Research , 2010 .
[147] W. Kuebler,et al. Lung Endothelial Dysfunction in Congestive Heart Failure: Role of Impaired Ca2+ Signaling and Cytoskeletal Reorganization , 2010, Circulation research.
[148] Natalia Novoselova,et al. Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection. , 2010, Microbes and infection.
[149] D. Howells,et al. Can Animal Models of Disease Reliably Inform Human Studies? , 2010, PLoS medicine.
[150] J. Whitsett,et al. Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice. , 2010, American journal of physiology. Lung cellular and molecular physiology.
[151] E. Weibel,et al. American Thoracic Society Documents An Official Research Policy Statement of the American Thoracic Society/European Respiratory Society: Standards for Quantitative Assessment of Lung Structure , 2010 .
[152] G. Joos,et al. Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation , 2010, Respiratory research.
[153] G. Hansmann,et al. Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization. , 2009, American journal of physiology. Lung cellular and molecular physiology.
[154] Kurt R Stenmark,et al. Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. , 2009, American journal of physiology. Lung cellular and molecular physiology.
[155] I. Cuthill,et al. Survey of the Quality of Experimental Design, Statistical Analysis and Reporting of Research Using Animals , 2009, PloS one.
[156] Daniel Becker,et al. cIAP-1 Controls Innate Immunity to C. pneumoniae Pulmonary Infection , 2009, PloS one.
[157] Y. Pinto,et al. Avoidance of Transient Cardiomyopathy in Cardiomyocyte-Targeted Tamoxifen-Induced MerCreMer Gene Deletion Models , 2009, Circulation research.
[158] J. Bastarache,et al. Development of animal models for the acute respiratory distress syndrome , 2009, Disease Models & Mechanisms.
[159] T. Welte,et al. Important Role for CC Chemokine Ligand 2-Dependent Lung Mononuclear Phagocyte Recruitment to Inhibit Sepsis in Mice Infected with Streptococcus pneumoniae 1 , 2009, The Journal of Immunology.
[160] Klaus Schughart,et al. Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections , 2009, PloS one.
[161] M. Kolb,et al. Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study , 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[162] J. Whitsett,et al. Conditional expression of genes in the respiratory epithelium in transgenic mice: cautionary notes and toward building a better mouse trap. , 2009, American journal of respiratory cell and molecular biology.
[163] A. Nials,et al. Mouse models of allergic asthma: acute and chronic allergen challenge , 2008, Disease Models & Mechanisms.
[164] N. Frossard,et al. Overexpression of functional TrkA receptors after internalisation in human airway smooth muscle cells. , 2008, Biochimica et biophysica acta.
[165] S. Shapiro. The use of transgenic mice for modeling airways disease. , 2008, Pulmonary pharmacology & therapeutics.
[166] T. Martin,et al. Animal models of acute lung injury , 2008, American journal of physiology. Lung cellular and molecular physiology.
[167] W. D. de Lange,et al. Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles. , 2008, Physiological genomics.
[168] N. Kirschvink,et al. Use of alternative animals as asthma models. , 2008, Current drug targets.
[169] T. Farncombe,et al. Journal of Translational Medicine Comparison between Conventional and "clinical" Assessment of Experimental Lung Fibrosis , 2008 .
[170] M. Jordana,et al. Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling. , 2008, American journal of respiratory and critical care medicine.
[171] C. Hogaboam,et al. Murine models of pulmonary fibrosis. , 2008, American journal of physiology. Lung cellular and molecular physiology.
[172] D. Warburton,et al. The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? , 2008, The international journal of biochemistry & cell biology.
[173] K. Williams,et al. Imaging diagnosis--Feline idiopathic pulmonary fibrosis. , 2008, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.
[174] Stefan Offermanns,et al. G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension , 2008, Nature Medicine.
[175] T. Holt,et al. Pulmonary arterial pressure testing for high mountain disease in cattle. , 2007, The Veterinary clinics of North America. Food animal practice.
[176] C. Garrido,et al. TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis1 , 2007, The Journal of Immunology.
[177] G. Bernard,et al. Acute lung injury and the acute respiratory distress syndrome: a clinical review , 2007, The Lancet.
[178] K. Preissner,et al. Importance of Phosphoinositide 3-Kinase γ in the Host Defense against Pneumococcal Infection , 2007 .
[179] In Ho Park,et al. Discovery of a New Capsular Serotype (6C) within Serogroup 6 of Streptococcus pneumoniae , 2007, Journal of Clinical Microbiology.
[180] Carla M. T. Bauer,et al. Animal models of chronic obstructive pulmonary disease exacerbations. , 2007, Contributions to microbiology.
[181] K. Preissner,et al. Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection. , 2007, American journal of respiratory and critical care medicine.
[182] S. Holgate,et al. The mouse trap: It still yields few answers in asthma. , 2006, American journal of respiratory and critical care medicine.
[183] J. Vincent,et al. Why do patients who have acute lung injury/acute respiratory distress syndrome die from multiple organ dysfunction syndrome? Implications for management. , 2006, Clinics in chest medicine.
[184] M. Ege,et al. The asthma epidemic. , 2006, The New England journal of medicine.
[185] R. Pauwels,et al. Murine models of COPD. , 2006, Pulmonary pharmacology & therapeutics.
[186] P. Gounon,et al. RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse , 2006, Nature.
[187] R. Simon,et al. Expression of the reverse tetracycline-transactivator gene causes emphysema-like changes in mice. , 2006, American journal of respiratory cell and molecular biology.
[188] N. Suttorp,et al. Detection of allergen-induced airway hyperresponsiveness in isolated mouse lungs. , 2006, American journal of physiology. Lung cellular and molecular physiology.
[189] Steffen Jung,et al. The inflammatory versus constitutive trafficking of mononuclear phagocytes into the alveolar space of mice is associated with drastic changes in their gene expression profiles , 2006 .
[190] P. Janmey,et al. Tissue Cells Feel and Respond to the Stiffness of Their Substrate , 2005, Science.
[191] H. Renz,et al. Involvement of distal airways in a chronic model of experimental asthma , 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[192] K. Desai,et al. Increased Fibulin-5 and Elastin in S100A4/Mts1 Mice With Pulmonary Hypertension , 2005, Circulation research.
[193] R. Pauwels,et al. Short-term cigarette smoke exposure enhances allergic airway inflammation in mice. , 2005, American journal of respiratory and critical care medicine.
[194] Yee Hwa Yang,et al. Freshly isolated rat alveolar type I cells, type II cells, and cultured type II cells have distinct molecular phenotypes. , 2005, American journal of physiology. Lung cellular and molecular physiology.
[195] Eberhard Durr,et al. Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture , 2004, Nature Biotechnology.
[196] W. Seeger,et al. Pneumolysin-Induced Lung Injury Is Independent of Leukocyte Trafficking into the Alveolar Space1 , 2004, The Journal of Immunology.
[197] D. Malarkey,et al. Identification of spontaneous feline idiopathic pulmonary fibrosis: morphology and ultrastructural evidence for a type II pneumocyte defect. , 2004, Chest.
[198] S. Czinn,et al. Bacterial Probiotic Modulation of Dendritic Cells , 2004, Infection and Immunity.
[199] M. Vidal,et al. A keratin K5Cre transgenic line appropriate for tissue‐specific or generalized cre‐mediated recombination , 2004, Genesis.
[200] N. Ambartsumian,et al. S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy. , 2004, The American journal of pathology.
[201] C. Johnson,et al. Identification and characterization of an idiopathic pulmonary fibrosis-like condition in cats. , 2004, Journal of veterinary internal medicine.
[202] A. T. Have-Opbroek. The structural composition of the pulmonary acinus in the mouse , 2004, Anatomy and Embryology.
[203] M. Kojima,et al. Mouse model of airway remodeling: strain differences. , 2003, American journal of respiratory and critical care medicine.
[204] Derek C Angus,et al. Community-acquired pneumonia in the elderly. , 2003, Critical care clinics.
[205] J. Wedzicha,et al. COPD exacerbations: definitions and classifications , 2003, European Respiratory Journal.
[206] A. Kay,et al. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. , 2003, American journal of respiratory and critical care medicine.
[207] E. Tuomanen,et al. Organ-specific models of Streptococcus pneumoniae Disease , 2003, Scandinavian journal of infectious diseases.
[208] Kim Bottomly,et al. Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen , 2002, The Journal of experimental medicine.
[209] Andrew P McMahon,et al. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. , 2002, Developmental biology.
[210] U. Kodavanti,et al. Pulmonary gene expression profiles of spontaneously hypertensive rats exposed to environmental tobacco smoke. , 2002, Chest.
[211] J. Phillips,et al. Specific bone morphogenic protein receptor II mutations found in primary pulmonary hypertension cause different biochemical phenotypes in vitro. , 2002, Chest.
[212] K. Kwan. Conditional alleles in mice: Practical considerations for tissue‐specific knockouts , 2002, Genesis.
[213] Y. Ohno,et al. ICH guidelines--implementation of the 3Rs (refinement, reduction, and replacement): incorporating best scientific practices into the regulatory process. , 2002, ILAR journal.
[214] P. Andrew,et al. Role of Genetic Resistance in Invasive Pneumococcal Infection: Identification and Study of Susceptibility and Resistance in Inbred Mouse Strains , 2001, Infection and Immunity.
[215] M. Capecchi,et al. Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[216] G. Feng,et al. Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP , 2000, Neuron.
[217] M. d’Ortho,et al. Inhibition of Matrix Metalloproteinases by Lung TIMP-1 Gene Transfer or Doxycycline Aggravates Pulmonary Hypertension in Rats , 2000, Circulation research.
[218] D. Schoenfeld,et al. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. , 2000, The New England journal of medicine.
[219] B. Thyagarajan,et al. Mammalian genomes contain active recombinase recognition sites. , 2000, Gene.
[220] C. Lobe,et al. Targeted insertion of Cre recombinase into the TNAP gene: Excision in primordial germ cells , 2000, Genesis.
[221] S. Shapiro,et al. Animal models for chronic obstructive pulmonary disease: age of klotho and marlboro mice. , 2000, American journal of respiratory cell and molecular biology.
[222] T. Marrie. Pneumococcal pneumonia: epidemiology and clinical features. , 1999, Seminars in respiratory infections.
[223] Sheldon P Stone,et al. Community-acquired pneumonia , 1998, The Lancet.
[224] M. Sagy,et al. A comparison among animal models of acute lung injury. , 1998, Critical care medicine.
[225] R. Naeije. Pulmonary circulation at high altitude. , 1997, Respiration; international review of thoracic diseases.
[226] M. Nelson,et al. Nutrient intakes, vitamin–mineral supplementation, and intelligence in British schoolchildren , 1990, British Journal of Nutrition.
[227] A. Esposito,et al. An Assessment of the Respiratory Burst and Bactericidal Activity of Alveolar Macrophages From Adult and Senescent Mice , 1988, Journal of leukocyte biology.
[228] A. A. ten Have-Opbroek. The structural composition of the pulmonary acinus in the mouse. A scanning electron microscopical and developmental-biological analysis. , 1986, Anatomy and embryology.