Contour extraction of left ventricular cavity from digital subtraction angiograms using a neural edge detector

In this paper, a supervised edge detector based on a multilayer neural network, which is called a neural edge detector (NED), is proposed for detecting edges which coincide with edges traced by a human operator (e.g., a medical doctor). The NED is trained by use of the contours traced by a cardiologist. Using the trained NED, the contours coinciding well with the contours traced by a cardiologist are extracted from the left ventricular angiograms even with nonuniform contrast medium. The proposed contour extraction method consists of (1) detection of fine edges by the NED, (2) extraction of rough contours, and (3) contour tracing based on contour candidates synthesized from the rough contours and the edges detected by the NED. The contour of the left ventricle is automatically extracted by inputting two points manually. Experiments with clinical images show that the proposed method can stably extract the contours coinciding well with the contours traced by a cardiologist. © 2003 Wiley Periodicals, Inc. Syst Comp Jpn, 34(2): 55–69, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/scj.1190

[1]  S Akselrod,et al.  An automatic contour extraction algorithm for short-axis cardiac magnetic resonance images. , 1996, Medical physics.

[2]  C T Chen,et al.  Epicardial boundary detection using fuzzy reasoning. , 1991, IEEE transactions on medical imaging.

[3]  John F. Canny,et al.  A Computational Approach to Edge Detection , 1986, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[4]  Hiroshi Nagahashi,et al.  Boundary detection of color images using neural networks , 1995, Proceedings of ICNN'95 - International Conference on Neural Networks.

[5]  James D. Thomas,et al.  Segmentation and tracking in echocardiographic sequences: active contours guided by optical flow estimates , 1998, IEEE Transactions on Medical Imaging.

[6]  Richard O. Duda,et al.  Pattern classification and scene analysis , 1974, A Wiley-Interscience publication.

[7]  P. Grattoni,et al.  Contour Detection of the Left Ventricular Cavity from Angiographic Images , 1985, IEEE Transactions on Medical Imaging.

[8]  Kenji Suzuki,et al.  Designing the optimal structure of a neural filter , 1998, Neural Networks for Signal Processing VIII. Proceedings of the 1998 IEEE Signal Processing Society Workshop (Cat. No.98TH8378).

[9]  D Marr,et al.  Theory of edge detection , 1979, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[10]  Essam A. El-Kwae,et al.  Edge detection in medical images using a genetic algorithm , 1998, IEEE Transactions on Medical Imaging.

[11]  C. C. Li,et al.  Automated left ventricular border determination in cineangiograms based on a dynamic spider model , 1990, [1990] Proceedings Computers in Cardiology.

[12]  Pekka J. Toivanen,et al.  Edge Detection of Multispectral Images Using the 1-D Self-Organizing Map , 1998 .

[13]  D.L. Parker,et al.  Improving left ventricular border recognition using probability surfaces , 1988, Proceedings. Computers in Cardiology 1988.

[14]  Demetri Terzopoulos,et al.  Snakes: Active contour models , 2004, International Journal of Computer Vision.

[15]  Ken-ichi Funahashi,et al.  On the approximate realization of continuous mappings by neural networks , 1989, Neural Networks.

[16]  M Rigaud,et al.  Variability and reproducibility of quantitative left ventricular angiography. , 1989, Catheterization and cardiovascular diagnosis.

[17]  M Demi New approach to automatic contour detection from image sequences: an application to ventriculographic images. , 1994, Computers and biomedical research, an international journal.

[18]  Takao Hinamoto,et al.  Image restoration by Hopfield networks considering the line process , 1995, Proceedings of ICNN'95 - International Conference on Neural Networks.

[19]  Koji Tochinai,et al.  An edge detection by using self-organization , 1998, Proceedings of the 1998 IEEE International Conference on Acoustics, Speech and Signal Processing, ICASSP '98 (Cat. No.98CH36181).

[20]  Surendra Ranganath,et al.  Contour extraction from cardiac MRI studies using snakes , 1995, IEEE Trans. Medical Imaging.

[21]  J Jenkins,et al.  Automatic Contour Definition on Left Ventriculograms By Image Evidence and a Multiple Template-Based Model (Cardiology) , 1989, IEEE transactions on medical imaging.

[22]  Ling Guan,et al.  Neural vision system and applications in image processing and analysis , 1998, Proceedings of the 1998 IEEE International Conference on Acoustics, Speech and Signal Processing, ICASSP '98 (Cat. No.98CH36181).

[23]  James L. McClelland,et al.  Parallel distributed processing: explorations in the microstructure of cognition, vol. 1: foundations , 1986 .

[24]  Jim R. Parker,et al.  Algorithms for image processing and computer vision , 1996 .

[25]  Manfred H. Hueckel An Operator Which Locates Edges in Digitized Pictures , 1971, J. ACM.

[26]  N. Otsu A threshold selection method from gray level histograms , 1979 .

[27]  Riccardo Poli,et al.  Recovery of the 3-D shape of the left ventricle from echocardiographic images , 1995, IEEE Trans. Medical Imaging.

[28]  Joos Vandewalle,et al.  Precise edge detection: representation by Boolean functions, implementation on the CNN , 1998, 1998 Fifth IEEE International Workshop on Cellular Neural Networks and their Applications. Proceedings (Cat. No.98TH8359).

[29]  Hideo Fujimoto,et al.  Edge detection by neural network with line process , 1993, Proceedings of 1993 International Conference on Neural Networks (IJCNN-93-Nagoya, Japan).

[30]  Krishnan B. Chandran,et al.  Automatic detection of left ventricular endocardium in cardiac images , 1990, [1990] Proceedings Computers in Cardiology.

[31]  A. Hallstrom,et al.  Reproducibility of ventricular function measurements by contrast angiography. , 1984, Catheterization and cardiovascular diagnosis.

[32]  J. Sau,et al.  Automated detection of the left ventricular region in gated nuclear cardiac imaging , 1996, IEEE Transactions on Biomedical Engineering.

[33]  Andrew R. Barron,et al.  Universal approximation bounds for superpositions of a sigmoidal function , 1993, IEEE Trans. Inf. Theory.

[34]  G Bashein,et al.  Matched filter identification of left-ventricular endocardial borders in transesophageal echocardiograms. , 1990, IEEE transactions on medical imaging.

[35]  James S. Duncan,et al.  Knowledge Directed Left Ventricular Boundary Detection in Equilibrium Radionuclide Angiocardiography , 1987, IEEE Transactions on Medical Imaging.

[36]  T L Faber,et al.  A model-based four-dimensional left ventricular surface detector. , 1991, IEEE transactions on medical imaging.

[37]  Geoffrey E. Hinton,et al.  Learning internal representations by error propagation , 1986 .

[38]  Jerry L. Prince,et al.  Tag and contour detection in tagged MR images of the left ventricle , 1994, IEEE Trans. Medical Imaging.

[39]  Csaba Rekeczky,et al.  Image segmentation and edge detection via constrained diffusion and adaptive morphology: a CNN approach to bubble/debris image enhancement , 1997 .

[40]  Abdel-Ouahab Boudraa,et al.  Left ventricle automated detection method in gated isotopic ventriculography using fuzzy clustering , 1993, IEEE Trans. Medical Imaging.

[41]  Jorge S. Marques,et al.  Unified approach to snakes, elastic nets and Kohonen maps , 1995, 1995 International Conference on Acoustics, Speech, and Signal Processing.

[42]  E J Delp,et al.  Detecting left ventricular endocardial and epicardial boundaries by digital two-dimensional echocardiography. , 1988, IEEE transactions on medical imaging.

[43]  Tamás Roska,et al.  CNN‐based difference‐controlled adaptive non‐linear image filters , 1998 .