Ganglion cyst of the temporomandibular joint.

We report a case of cystic lesion in a 37-year-old woman. The patient had an oval-shaped lesion adjacent to the temporomandibular joint. Thick fibrotic tissue and muscle were observed microscopically, but the epithelium lining was not observed. The lesion was diagnosed as a ganglion cyst. The patient's general medical history was non-contributory. High performance liquid chromatography (HPLC) and mass spectrophotometry (MS) revealed some proteins from the fluid in the lesion, such as a filaggrin precursor, dystroglycan, a polyprotein of the hepatitis C virus, and proteins originating from bacteria. The follow-up examinations revealed no recurrence. The probable pathogenesis of the lesion is discussed.

[1]  Filip De Keyser,et al.  Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium: Relevance to antifilaggrin autoantibodies , 2001 .

[2]  Albert Lj Infection and rheumatoid arthritis: guilt by association? , 2000 .

[3]  B. Mazières,et al.  Immunoblotting detection of autoantibodies to human epidermis filaggrin: a new diagnostic test for rheumatoid arthritis. , 1998, The Journal of rheumatology.

[4]  S. Hao,et al.  Ganglion cyst and synovial cyst of the temporomandibular joint. Two case reports. , 1997, International journal of oral and maxillofacial surgery.

[5]  P. Steinert,et al.  The Proteins Elafin, Filaggrin, Keratin Intermediate Filaments, Loricrin, and Small Proline-rich Proteins 1 and 2 Are Isodipeptide Cross-linked Components of the Human Epidermal Cornified Cell Envelope (*) , 1995, The Journal of Biological Chemistry.

[6]  K. Davies,et al.  G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[7]  U. Francke,et al.  Human dystroglycan: skeletal muscle cDNA, genomic structure, origin of tissue specific isoforms and chromosomal localization. , 1993, Human molecular genetics.

[8]  R. F. Morgan,et al.  Recognizing the temporomandibular joint ganglion. , 1987, Annals of plastic surgery.

[9]  P. F. Wallace,et al.  The dorsal ganglion of the wrist: its pathogenesis, gross and microscopic anatomy, and surgical treatment. , 1976, The Journal of hand surgery.