Model of Drugs Penetration Through Biological Membrane

This work deals with pharmacokinetics modeling and compilation of functional models. There are three mathematical models representing actions beginning intravascular drug administration until the elimination from the body. Graphics dependences are outputs of these models, provide a quick idea about behavior of drugs in the body and time period, when is medicine completely eliminated. The main model illustrates the penetration of drug across biological membrane using the same principles, but the model tells of what happens to take place on bio membranes and its surrounding area.

[1]  Iveta Bryjova,et al.  Education of Biomedical Engineering in the Technical University of Ostrava , 2014 .

[2]  Marek Penhaker,et al.  Measurement and Diagnosis Assessment of Plethysmographycal Record , 2011 .

[3]  M. Penhaker,et al.  Sensitivity analysis and application of transducers , 2008, 2008 5th International Summer School and Symposium on Medical Devices and Biosensors.

[4]  Martin Augustynek,et al.  Notice of Retraction Controlling Peacemakers by Accelerometers , 2010 .

[5]  Marek Penhaker,et al.  Evaluation of Electrocardiographic Leads and Establishing Significance Intra-individuality , 2013, IBICA.

[6]  Martin Augustynek,et al.  Finger Plethysmography Classification by Orthogonal Transformatios , 2010 .

[7]  M. Penhaker,et al.  Wireless Body Sensor Network in Health Maintenance Systems , 2011 .

[8]  M. Penhaker,et al.  The HomeCare and Circadian rhythm , 2008, 2008 International Conference on Information Technology and Applications in Biomedicine.

[9]  Dietmar P. F. Möller,et al.  Biomedical Modeling and Simulation on a PC: A Workbench for Physiology and Biomedical Engineering , 2011 .

[10]  Yves Chevalier,et al.  Penetration of drugs through skin, a complex rate-controlling membrane , 2012 .

[11]  Martin Cerný,et al.  Circadian Rhythm Evaluation Using Fuzzy Logic , 2013, Advanced Methods for Computational Collective Intelligence.

[12]  A. Ladokhin Measuring membrane penetration with depth-dependent fluorescence quenching: distribution analysis is coming of age. , 2014, Biochimica et biophysica acta.