Intratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential

[1]  P. Fowler,et al.  Development of the human fetal testis. , 2014, Annales d'endocrinologie.

[2]  E. R. Meyts,et al.  Dysregulation of the mitosis–meiosis switch in testicular carcinoma in situ , 2013, The Journal of pathology.

[3]  Yao-Tseng Chen,et al.  Chromosome X-encoded Cancer/Testis antigens are less frequently expressed in non-seminomatous germ cell tumors than in seminomas. , 2013, Cancer immunity.

[4]  N. Skakkebæk,et al.  Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells , 2010, British Journal of Cancer.

[5]  R. Sharpe,et al.  Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation , 2010, Human reproduction.

[6]  R. Sharpe,et al.  Germ cell differentiation in the marmoset (Callithrix jacchus) during fetal and neonatal life closely parallels that in the human , 2008, Human reproduction.

[7]  L. Looijenga,et al.  Chromosomes and Expression in Human Testicular Germ‐Cell Tumors , 2007, Annals of the New York Academy of Sciences.

[8]  E. Rajpert-De Meyts Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects. , 2006, Human reproduction update.

[9]  E. Steyerberg,et al.  Morphological and immunohistochemical differences between gonadal maturation delay and early germ cell neoplasia in patients with undervirilization syndromes. , 2005, The Journal of clinical endocrinology and metabolism.

[10]  H. Leffers,et al.  Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours , 2005, Histopathology.

[11]  Yun-Fai Chris Lau,et al.  Identification of germ cells at risk for neoplastic transformation in gonadoblastoma: an immunohistochemical study for OCT3/4 and TSPY. , 2005, Human pathology.

[12]  L. Looijenga,et al.  Testicular germ-cell tumours in a broader perspective , 2005, Nature Reviews Cancer.

[13]  H. Leffers,et al.  Transcription Factor AP-2γ Is a Developmentally Regulated Marker of Testicular Carcinoma In situ and Germ Cell Tumors , 2004, Clinical Cancer Research.

[14]  Liang Cheng,et al.  OCT4: A sensitive and specific biomarker for intratubular germ cell neoplasia of the testis. , 2004, Clinical cancer research : an official journal of the American Association for Cancer Research.

[15]  P. Saunders,et al.  Immunohistochemical Profiling of Germ Cells Within the Human Fetal Testis: Identification of Three Subpopulations , 2004, Biology of reproduction.

[16]  H. Adami,et al.  Testicular cancer incidence in eight northern European countries: secular and recent trends. , 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[17]  Christian Schwager,et al.  Embryonic Stem Cell-Like Features of Testicular Carcinoma in Situ Revealed by Genome-Wide Gene Expression Profiling , 2004, Cancer Research.

[18]  C. Bokemeyer,et al.  Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells , 2004, The Journal of pathology.

[19]  N. Skakkebaek,et al.  Developmental expression of POU5F1 (OCT-3/4) in normal and dysgenetic human gonads. , 2004, Human reproduction.

[20]  J. Kononen,et al.  POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors. , 2003, Cancer research.

[21]  J. Bartek,et al.  The emerging phenotype of the testicular carcinoma in situ germ cell , 2003, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[22]  L. Brown,et al.  Trends in the incidence of testicular germ cell tumors in the United States , 2003, Cancer.

[23]  L. Looijenga,et al.  VASA Is a Specific Marker for Both Normal and Malignant Human Germ Cells , 2002, Laboratory Investigation.

[24]  P. Chomez,et al.  MAGE‐A4, a germ cell specific marker, is expressed differentially in testicular tumors , 2001, Cancer.

[25]  B. Quade,et al.  The human VASA gene is specifically expressed in the germ cell lineage. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[26]  A. Renshaw,et al.  Evaluation of Cyclin Expression in Testicular Germ Cell Tumors: Cyclin E Correlates with Tumor Type, Advanced Clinical Stage, and Pulmonary Metastasis , 2000, Modern Pathology.

[27]  P. Albers,et al.  Tumor proliferative activity is predictive of pathological stage in clinical stage A nonseminomatous testicular germ cell tumors. , 1996, The Journal of urology.

[28]  N. Skakkebaek,et al.  Expression of immunohistochemical markers for testicular carcinoma in situ by normal human fetal germ cells. , 1995, Laboratory investigation; a journal of technical methods and pathology.

[29]  A. Norton,et al.  Brief, high‐temperature heat denaturation (pressure cooking): A simple and effective method of antigen retrieval for routinely processed tissues , 1994, The Journal of pathology.

[30]  N. Skakkebaek,et al.  Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma. , 1987, International journal of andrology.

[31]  J. Hustin,et al.  Immunohistochemical demonstration of placental alkaline phosphatase in various states of testicular development and in germ cell tumours. , 1987, International journal of andrology.

[32]  P. W. Adams,et al.  VITAMIN B6, DEPRESSION, AND ORAL CONTRACEPTION , 1974 .

[33]  N. Skakkebæk POSSIBLE CARCINOMA-IN-SITU OF THE TESTIS , 1972 .

[34]  N. Skakkebaek,et al.  Possible carcinoma-in-situ of the testis. , 1972, Lancet.