On the symmetry between eyes of wavefront aberration and cone directionality

There are two optical processes that control the retinal image sampled by the photoreceptor array: aberrations of the ocular optics and cone directionality (Stiles-Crawford effect). The shape of wavefront aberration and Stiles-Crawford functions are known to vary markedly across subjects. In this study we investigate in twelve subjects the symmetry between right and left eyes of wavefront aberration (measured using a spatially resolved refractometer) and cone directionality (measured using an imaging reflectometric technique). The pattern of aberrations is in general non-symmetric, suggesting that the development of aberrations follow independent paths in many right and left eye pairs. Cone directionality is in most cases mirror-symmetric (with one case of direct symmetry), suggesting some systematic process underlying cone orientation. Except in two subjects, symmetry in these two functions seems to be unrelated. Cone directionality apodization improves optical quality, but not optimally in all eyes, and it does not tend to increase symmetry in the optical performance of left and right eyes.

[1]  M. Losada,et al.  Aberrations and Relative Efficiency of Light Pencils in the Living Human Eye , 1997, Optometry and vision science : official publication of the American Academy of Optometry.

[2]  D A Atchison,et al.  Influence of Stiles-Crawford effect apodization on spatial visual performance. , 1998, Journal of the Optical Society of America. A, Optics, image science, and vision.

[3]  G. M. Morris,et al.  Images of cone photoreceptors in the living human eye , 1996, Vision Research.

[4]  K P Thompson,et al.  Measurement of ocular local wavefront distortion with a spatially resolved refractometer. , 1992, Applied optics.

[5]  B. Howland,et al.  A subjective method for the measurement of monochromatic aberrations of the eye. , 1977, Journal of the Optical Society of America.

[6]  J. Pokorny,et al.  Visual function in acute posterior multifocal placoid pigment epitheliopathy. , 1978, American journal of ophthalmology.

[7]  A Bradley,et al.  Apodization by the Stiles-Crawford effect moderates the visual impact of retinal image defocus. , 1999, Journal of the Optical Society of America. A, Optics, image science, and vision.

[8]  Satterfield Ds.  Prevalence and variation of astigmatism in a military population. , 1989 .

[9]  R. Noll.  Zernike polynomials and atmospheric turbulence , 1976 .

[10]  W N Charman,et al.  Objective technique for the determination of monochromatic aberrations of the human eye. , 1984, Journal of the Optical Society of America. A, Optics and image science.

[11]  J M Enoch,et al.  Stability of the Stiles-Crawford function in a unilateral amblyopic subject over a 38-year period: a case study. , 1995, Optometry and vision science : official publication of the American Academy of Optometry.

[12]  L. M. Almeder,et al.  Prevalence of anisometropia in volunteer laboratory and school screening populations. , 1990, Investigative ophthalmology & visual science.

[13]  D. Birch,et al.  Evidence for alteration in photoreceptor orientation. , 1980, Ophthalmology.

[14]  D. Van Norren,et al.  Photoreceptor function in unilateral amblyopia , 1998, Vision Research.

[15]  V. Mahajan.  Zernike circle polynomials and optical aberrations of systems with circular pupils. , 1994, Applied optics.

[16]  Stephen A. Burns,et al.  A new approach to the study of ocular chromatic aberrations , 1999, Vision Research.

[17]  A. Hendrickson,et al.  Human photoreceptor topography , 1990, The Journal of comparative neurology.

[18]  S A Burns,et al.  Direct measurement of human-cone-photoreceptor alignment. , 1995, Journal of the Optical Society of America. A, Optics, image science, and vision.

[19]  R A Applegate,et al.  Parametric representation of Stiles-Crawford functions: normal variation of peak location and directionality. , 1993, Journal of the Optical Society of America. A, Optics and image science.

[20]  D. Satterfield.  Prevalence and variation of astigmatism in a military population. , 1989, Journal of the American Optometric Association.

[21]  S A Burns,et al.  Cone spacing and waveguide properties from cone directionality measurements. , 1999, Journal of the Optical Society of America. A, Optics, image science, and vision.

[22]  S A Burns,et al.  Comparison of cone directionality determined by psychophysical and reflectometric techniques. , 1999, Journal of the Optical Society of America. A, Optics, image science, and vision.

[23]  J M ENOCH.  Receptor amblyopia. , 1959, American journal of ophthalmology.

[24]  F. Delori,et al.  A reflectometric technique for assessing photorecelptor alignment , 1995, Vision Research.

[25]  Junzhong Liang,et al.  Aberrations and retinal image quality of the normal human eye. , 1997, Journal of the Optical Society of America. A, Optics, image science, and vision.

[26]  R A Applegate,et al.  Induced movement of receptor alignment toward a new pupillary aperture. , 1981, Investigative ophthalmology & visual science.

[27]  P Artal,et al.  Effects of aging in retinal image quality. , 1993, Journal of the Optical Society of America. A, Optics and image science.

[28]  S A Burns,et al.  Model for cone directionality reflectometric measurements based on scattering. , 1998, Journal of the Optical Society of America. A, Optics, image science, and vision.

[29]  S A Burns,et al.  Measurement of the wave-front aberration of the eye by a fast psychophysical procedure. , 1998, Journal of the Optical Society of America. A, Optics, image science, and vision.

[30]  A. McKendrick,et al.  The Axis of Astigmatism in Right and Left Eye Pairs , 1997, Optometry and vision science : official publication of the American Academy of Optometry.

[31]  A. van Meeteren,et al.  Calculations on the Optical Modulation Transfer Function of the Human Eye for White Light , 1974 .

[32]  J M Enoch,et al.  MARKED ACCOMMODATION, RETINAL STRETCH, MONOCULAR SPACE PERCEPTION AND RETINAL RECEPTOR ORIENTATION * , 1975, American journal of optometry and physiological optics.

[33]  W. Stiles,et al.  Luminous Efficiency of Rays entering the Eye Pupil at Different Points , 1937, Nature.

[34]  A displaced Stiles-Crawford effect associated with an eccentric pupil. , 1978, Investigative ophthalmology & visual science.

[35]  李幼升,et al.  Ph , 1989 .

[36]  P Artal,et al.  Coherent imaging of the cone mosaic in the living human eye. , 1996, Journal of the Optical Society of America. A, Optics, image science, and vision.