A Half-Subtracter Calculation Model Based on Stand Displacement Technology

In this work, we construct a half-subtracter calculation model with the principle of complementary base pairs and the technology of fluorescence labeling through the combination of INH and XOR calculation model. We implement the calculation process of a half-subtracter utilizing the strand displacement technology that two DNA signal strands as the input signal and the intensity of fluorescence as the output signal. The sequence of strands used in the experiment is designed by NUPACK. The simulation experiment is constructed with Visual DSD which is convenient to analyze the experiment results. The results show that the model performs well with high stability and feasibility and decreases the complexity of calculation.

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