论文信息 - Fast laser scanning optical-CT apparatus for 3D radiation dosimetry

Fast laser scanning optical-CT apparatus for 3D radiation dosimetry

Optical computed tomography (optical-CT) of 3D radiation dosimeters is a promising avenue for delivering an economic and reliable quality control of radiotherapy treatments such as intensity modulated radiotherapy, brachytherapy and stereotactic radiosurgery. The main problems in transferring 3D dosimeters to clinical setting have been in (1) the complexity of manufacture and behaviour of 3D dosimeters and (2) time-consuming readout and analysis of 3D dosimeters. This paper addresses the readout problem by showing that fast (20 min tomography scan), precise (projection absorbance signal-to-noise ratio is greater than 100:1 across the absorbance range 0.2 to 1.5) and accurate (good linearity in the calibration curve) measurements are possible using a novel method of optically scanning a laser beam across the 3D dosimeter.

Nikola Krstajić | Simon J Doran | N. Krstajić | S. Doran

[1] J. Gore,et al. Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner. , 1996, Physics in medicine and biology.

[2] J G Wolodzko,et al. CCD imaging for optical tomography of gel radiation dosimeters. , 1999, Medical physics.

[3] M. Oldham,et al. Optical-CT gel-dosimetry I: basic investigations. , 2003, Medical physics.

[4] J Conklin,et al. Fast laser optical CT scanner with rotating mirror and Fresnel lenses , 2006 .

[6] T. Rutten,et al. A fast, high spatial resolution optical tomographic scanner for measurement of absorption in gel dosimetry , 2005, Australasian Physics & Engineering Sciences in Medicine.

[7] M. Oldham,et al. Optical-CT gel-dosimetry. II: Optical artifacts and geometrical distortion. , 2004, Medical physics.

[8] J. Dempsey,et al. Initial evaluation of commercial optical CT-based 3D gel dosimeter. , 2003, Medical physics.

[9] C. Wuu,et al. Performance of a commercial optical CT scanner and polymer gel dosimeters for 3-D dose verification. , 2004, Medical physics.

[10] N. Krstajić,et al. Focusing optics of a parallel beam CCD optical tomography apparatus for 3D radiation gel dosimetry , 2006, Physics in medicine and biology.

[11] S. Doran,et al. A CCD-based optical CT scanner for high-resolution 3D imaging of radiation dose distributions: equipment specifications, optical simulations and preliminary results , 2001 .