Control of flowering time: interacting pathways as a basis for diversity.

Flowering is controlled by environmental conditions and developmental regulation. The complexity of this regulation is created by an intricate network of signaling pathways. Arabidopsis is an excellent model system in which to approach this complexity, because it responds to many of the

[1]  C. Dean,et al.  When to switch to flowering. , 1999, Annual review of cell and developmental biology.

[2]  M. Koornneef,et al.  Flowering responses to light-breaks in photomorphogenic mutants of Arabidopsis thaliana, a long-day plant , 1991 .

[3]  E. M. Meyerowitz,et al.  Arabidopsis thaliana , 2022, CABI Compendium.

[4]  S. Roux,et al.  Antisense expression of the CK2 alpha-subunit gene in Arabidopsis. Effects on light-regulated gene expression and plant growth. , 1999, Plant physiology.

[5]  R. Amasino,et al.  Loss of FLOWERING LOCUS C Activity Eliminates the Late-Flowering Phenotype of FRIGIDA and Autonomous Pathway Mutations but Not Responsiveness to Vernalization , 2001, Plant Cell.

[6]  T. Araki,et al.  Transition from vegetative to reproductive phase. , 2001, Current opinion in plant biology.

[7]  Claire Périlleux,et al.  Mutagenesis of Plants Overexpressing CONSTANS Demonstrates Novel Interactions among Arabidopsis Flowering-Time Genes , 2000, Plant Cell.

[8]  S. Kay,et al.  Orchestrated transcription of key pathways in Arabidopsis by the circadian clock. , 2000, Science.

[9]  M. Ishitani,et al.  The Arabidopsis HOS1 gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold-regulated nucleo--cytoplasmic partitioning. , 2001, Genes & development.

[10]  J. Kreps,et al.  Environmental and genetic effects on circadian clock-regulated gene expression in Arabidopsis. , 1997, The Plant cell.

[11]  M. Koornneef,et al.  Induction and analysis of gibberellin sensitive mutants in Arabidopsis thaliana (L.) heynh. , 1980, Theoretical and Applied Genetics.

[12]  J. Langridge Effect of Day-length and Gibberellic Acid on the Flowering of Arabidopsis , 1957, Nature.

[13]  E. Tobin,et al.  Loss of the circadian clock-associated protein 1 in Arabidopsis results in altered clock-regulated gene expression. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[14]  C. Dean,et al.  Mapping FRI, a locus controlling flowering time and vernalization response in Arabidopsis thaliana , 2004, Molecular and General Genetics MGG.

[15]  M. Robertson,et al.  The Arabidopsis protein SHI represses gibberellin responses in Arabidopsis and barley. , 2001, Plant physiology.

[16]  T. Sun,et al.  The DELLA motif is essential for gibberellin-induced degradation of RGA , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[17]  Robert J. Schaffer,et al.  Microarray Analysis of Diurnal and Circadian-Regulated Genes in Arabidopsis , 2001, Plant Cell.

[18]  R. Fischer,et al.  Polycomb repression of flowering during early plant development , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[19]  C. Strayer,et al.  Circadian clock mutants in Arabidopsis identified by luciferase imaging , 1995, Science.

[20]  E. Huq,et al.  GIGANTEA is a nuclear protein involved in phytochrome signaling in Arabidopsis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[21]  R. Amasino,et al.  Isolation of LUMINIDEPENDENS: a gene involved in the control of flowering time in Arabidopsis. , 1994, The Plant cell.

[22]  Tai-Ping Sun,et al.  Gibberellin signaling: biosynthesis, catabolism, and response pathways. , 2002, The Plant cell.

[23]  R. Macknight,et al.  FCA , a Gene Controlling Flowering Time in Arabidopsis, Encodes a Protein Containing RNA-Binding Domains , 1997, Cell.

[24]  R. Amasino,et al.  Memories of winter: vernalization and the competence to flower , 2000 .

[25]  R. Amasino,et al.  Gibberellin response mutants identified by luciferase imaging. , 2001, The Plant Journal.

[26]  K. Borden RING fingers and B-boxes: zinc-binding protein-protein interaction domains. , 1998, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[27]  S. Shannon,et al.  Early-Flowering Mutants of Arabidopsis thaliana , 1992 .

[28]  S. Jacobsen,et al.  Mutations at the SPINDLY locus of Arabidopsis alter gibberellin signal transduction. , 1993, The Plant cell.

[29]  E. Tobin,et al.  The protein kinase CK2 is involved in regulation of circadian rhythms in Arabidopsis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[30]  L. Cooley,et al.  The kelch repeat superfamily of proteins: propellers of cell function. , 2000, Trends in cell biology.

[31]  Michael F. Covington,et al.  ELF3 Modulates Resetting of the Circadian Clock in Arabidopsis , 2001, The Plant Cell Online.

[32]  Tsuyoshi Mizoguchi,et al.  LHY and CCA1 are partially redundant genes required to maintain circadian rhythms in Arabidopsis. , 2002, Developmental cell.

[33]  D. E. Somers,et al.  Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog. , 2000, Science.

[34]  G. Hart,et al.  Dynamic Glycosylation of Nuclear and Cytosolic Proteins , 1997, The Journal of Biological Chemistry.

[35]  G. Coupland,et al.  The control of flowering time and floral identity in Arabidopsis. , 1998, Plant physiology.

[36]  L. Mcintosh,et al.  Isolation of a CONSTANS ortholog from Pharbitis nil and its role in flowering. , 2001, Plant physiology.

[37]  Anthony Hall,et al.  The ELF3 zeitnehmer regulates light signalling to the circadian clock , 2000, Nature.

[38]  P. Benfey,et al.  The GRAS gene family in Arabidopsis: sequence characterization and basic expression analysis of the SCARECROW-LIKE genes. , 1999, The Plant journal : for cell and molecular biology.

[39]  J. Ainscough,et al.  Clonal analysis of the late flowering fca mutant of Arabidopsis thaliana: cell fate and cell autonomy. , 1996, Development.

[40]  R. Vierstra,et al.  The Arabidopsis thaliana HY1 locus, required for phytochrome-chromophore biosynthesis, encodes a protein related to heme oxygenases. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[41]  A. Samach,et al.  Photoperiodism: The consistent use of CONSTANS , 2001, Current Biology.

[42]  Caren Chang,et al.  Arabidopsis RGL1 Encodes a Negative Regulator of Gibberellin Responses Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010325. , 2002, The Plant Cell Online.

[43]  U. Lagercrantz,et al.  Rapid evolution of the family of CONSTANS LIKE genes in plants. , 2000, Molecular biology and evolution.

[44]  Elliot M. Meyerowitz,et al.  Control of flower development in Arabidopsis thaliana by APETALA1 and interacting genes , 1993 .

[45]  ELF3 Encodes a Circadian Clock–Regulated Nuclear Protein That Functions in an Arabidopsis PHYB Signal Transduction Pathway , 2001, The Plant Cell Online.

[46]  D. Weigel,et al.  GAMYB-like genes, flowering, and gibberellin signaling in Arabidopsis. , 2001, Plant physiology.

[47]  M. Koornneef,et al.  A genetic and physiological analysis of late flowering mutants in Arabidopsis thaliana , 1991, Molecular and General Genetics MGG.

[48]  J. P. Jackson,et al.  The late flowering phenotype of fwa mutants is caused by gain-of-function epigenetic alleles of a homeodomain gene. , 2000, Molecular cell.

[49]  M. Ishitani,et al.  HOS1, a Genetic Locus Involved in Cold-Responsive Gene Expression in Arabidopsis , 1998, Plant Cell.

[50]  Rüdiger Simon,et al.  Activation of floral meristem identity genes in Arabidopsis , 1996, Nature.

[51]  M. Yano,et al.  Identification of quantitative trait loci controlling heading date in rice using a high-density linkage map , 1997, Theoretical and Applied Genetics.

[52]  W. Peacock,et al.  The FLF MADS Box Gene: A Repressor of Flowering in Arabidopsis Regulated by Vernalization and Methylation , 1999, Plant Cell.

[53]  G. Coupland,et al.  GIGANTEA: a circadian clock‐controlled gene that regulates photoperiodic flowering in Arabidopsis and encodes a protein with several possible membrane‐spanning domains , 1999, The EMBO journal.

[54]  F. Eisenhaber,et al.  Ubiquitylation in plants: a post-genomic look at a post-translational modification. , 2001, Trends in plant science.

[55]  G. Coupland,et al.  Response of plant development to environment: control of flowering by daylength and temperature. , 2000, Current opinion in plant biology.

[56]  C. Somerville,et al.  Effect of Light Quality and Vernalization on Late-Flowering Mutants of Arabidopsis thaliana. , 1990, Plant physiology.

[57]  P. Quail,et al.  Flowering Responses to Altered Expression of Phytochrome in Mutants and Transgenic Lines of Arabidopsis thaliana (L.) Heynh , 1995, Plant physiology.

[58]  Zhi-Yong Wang,et al.  Constitutive Expression of the CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) Gene Disrupts Circadian Rhythms and Suppresses Its Own Expression , 1998, Cell.

[59]  D. Wagner,et al.  Transcriptional activation of APETALA1 by LEAFY. , 1999, Science.

[60]  Detlef Weigel,et al.  A developmental switch sufficient for flower initiation in diverse plants , 1995, Nature.

[61]  T. Mockler,et al.  Regulation of flowering time by Arabidopsis photoreceptors. , 1998, Science.

[62]  R. Amasino,et al.  The late-flowering phenotype of FRIGIDA and mutations in LUMINIDEPENDENS is suppressed in the Landsberg erecta strain of Arabidopsis , 1994 .

[63]  Z. R. Sung,et al.  EMF genes regulate Arabidopsis inflorescence development. , 1997, The Plant cell.

[64]  R. Amasino,et al.  Analysis of naturally occurring late flowering in Arabidopsis thaliana , 1993, Molecular and General Genetics MGG.

[65]  D. Gage,et al.  Gibberellins and Stem Growth in Arabidopsis thaliana (Effects of Photoperiod on Expression of the GA4 and GA5 Loci) , 1997, Plant physiology.

[66]  D Weigel,et al.  Flowering-time genes modulate the response to LEAFY activity. , 1998, Genetics.

[67]  A. Peeters,et al.  GENETIC CONTROL OF FLOWERING TIME IN ARABIDOPSIS. , 1998, Annual review of plant physiology and plant molecular biology.

[68]  Z. R. Sung,et al.  Genetic regulation of shoot development in Arabidopsis: role of the EMF genes. , 1995, Developmental biology.

[69]  J. Chory,et al.  Activation tagging of the floral inducer FT. , 1999, Science.

[70]  Y. Kobayashi,et al.  A pair of related genes with antagonistic roles in mediating flowering signals. , 1999, Science.

[71]  D. Inzé,et al.  Cloning of a novel Arabidopsis thaliana RGA-like gene, a putative member of the VHIID-domain transcription factor family , 1998 .

[72]  Martha Merrow,et al.  Circadian clocks: Omnes viae Romam ducunt , 2000, Current Biology.

[73]  R. Amasino,et al.  The gibberellic acid biosynthesis mutant ga1-3 of Arabidopsis thaliana is responsive to vernalization. , 1999, Developmental genetics.

[74]  N. Chua,et al.  PAT1, a new member of the GRAS family, is involved in phytochrome A signal transduction. , 2000, Genes & development.

[75]  B. Bartel,et al.  FKF1, a Clock-Controlled Gene that Regulates the Transition to Flowering in Arabidopsis , 2000, Cell.

[76]  Shihshieh Huang,et al.  Overexpression of 20-oxidase confers a gibberellin-overproduction phenotype in Arabidopsis. , 1998, Plant Physiology.

[77]  D. Russenberger,et al.  FPF1 promotes flowering in Arabidopsis. , 1997, The Plant cell.

[78]  Michael F. Covington,et al.  ELF 3 Encodes a Circadian Clock – Regulated Nuclear Protein That Functions in an Arabidopsis PHYB Signal Transduction Pathway , 2001 .

[79]  A. Belachew,et al.  EMF, an Arabidopsis Gene Required for Vegetative Shoot Development , 1992, Science.

[80]  R. Amasino,et al.  Identification of a MADS-box gene, FLOWERING LOCUS M, that represses flowering. , 2001, The Plant journal : for cell and molecular biology.

[81]  T. Moritz,et al.  Gibberellins are not required for normal stem growth in Arabidopsis thaliana in the absence of GAI and RGA. , 2001, Genetics.

[82]  I. Hwang,et al.  The Arabidopsis Photomorphogenic Mutant hy1 Is Deficient in Phytochrome Chromophore Biosynthesis as a Result of a Mutation in a Plastid Heme Oxygenase , 1999, Plant Cell.

[83]  T. Sun,et al.  The Arabidopsis RGA Gene Encodes a Transcriptional Regulator Repressing the Gibberellin Signal Transduction Pathway , 1998, Plant Cell.

[84]  J. Ecker,et al.  An Arabidopsis circadian clock component interacts with both CRY1 and phyB , 2001, Nature.

[85]  E. Wisman,et al.  A MADS domain gene involved in the transition to flowering in Arabidopsis. , 2000, The Plant journal : for cell and molecular biology.

[86]  S. Roux,et al.  Antisense Expression of the CK 2 a-Subunit Gene in Arabidopsis . Effects on Light-Regulated Gene Expression and Plant Growth 1 , 1999 .

[87]  D. Weigel,et al.  Gibberellins Promote Flowering of Arabidopsis by Activating the LEAFY Promoter , 1998, Plant Cell.

[88]  D. E. Somers,et al.  ZEITLUPE Encodes a Novel Clock-Associated PAS Protein from Arabidopsis , 2000, Cell.

[89]  T. Kakutani Genetic characterization of late-flowering traits induced by DNA hypomethylation mutation in Arabidopsis thaliana. , 1997, The Plant journal : for cell and molecular biology.

[90]  E. Meyerowitz,et al.  A Polycomb-group gene regulates homeotic gene expression in Arabidopsis , 1997, Nature.

[91]  W. Peacock,et al.  DNA methylation, vernalization, and the initiation of flowering. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[92]  R. Yadegari,et al.  Mutations in FIE, a WD Polycomb Group Gene, Allow Endosperm Development without Fertilization , 1999, Plant Cell.

[93]  W. Peacock,et al.  Fertilization-independent seed development in Arabidopsis thaliana. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[94]  T. Mizuno,et al.  Genes encoding pseudo-response regulators: insight into His-to-Asp phosphorelay and circadian rhythm in Arabidopsis thaliana. , 2000, Plant & cell physiology.

[95]  U. Grossniklaus,et al.  Interaction of the Arabidopsis Polycomb group proteins FIE and MEA mediates their common phenotypes , 2000, Current Biology.

[96]  M Koornneef,et al.  Genetic interactions among late-flowering mutants of Arabidopsis. , 1998, Genetics.

[97]  Z. R. Sung,et al.  EMBRYONIC FLOWER2, a Novel Polycomb Group Protein Homolog, Mediates Shoot Development and Flowering in Arabidopsis Article, publication date, and citation information can be found at www.aspb.org/cgi/doi/10.1105/tpc.010227. , 2001, The Plant Cell Online.

[98]  D. R. Wagner,et al.  EARLY FLOWERING3 Encodes a Novel Protein That Regulates Circadian Clock Function and Flowering in Arabidopsis , 2001, The Plant Cell Online.

[99]  M. Yano,et al.  Identification of heading date quantitative trait locus Hd6 and characterization of its epistatic interactions with Hd2 in rice using advanced backcross progeny. , 2000, Genetics.

[100]  E. Tobin,et al.  Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[101]  E. Coen,et al.  Inflorescence Commitment and Architecture in Arabidopsis , 1997, Science.

[102]  G. Takeba,et al.  Translocation of the Floral Stimulus in Pharbitis nil , 1966 .

[103]  B. Thomas,et al.  Developmental and photobiological factors affecting photoperiodic induction in Arabidopsis thaliana Heynh. Landsberg erecta , 1995 .

[104]  T. Sun,et al.  The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis. , 1994, The Plant cell.

[105]  T. Kakutani,et al.  Developmental abnormalities and epimutations associated with DNA hypomethylation mutations. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[106]  N. Harberd,et al.  Photoresponses of Light-Grown phyA Mutants of Arabidopsis (Phytochrome A Is Required for the Perception of Daylength Extensions) , 1994, Plant physiology.

[107]  F. Bonhomme,et al.  Cytokinin and gibberellin activate SaMADS A, a gene apparently involved in regulation of the floral transition in Sinapis alba. , 2000, The Plant journal : for cell and molecular biology.

[108]  E. Huq,et al.  Direct targeting of light signals to a promoter element-bound transcription factor. , 2000, Science.

[109]  M. Tyers,et al.  Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. , 1998, Trends in genetics : TIG.

[110]  M. Koornneef,et al.  The phenotype of some late-flowering mutants is enhanced by a locus on chromosome 5 that is not effective in the Landsberg erecta wild-type , 1994 .

[111]  J. S. Lee,et al.  The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis. , 2000, Genes & development.

[112]  D. E. Somers,et al.  Control of circadian rhythms and photoperiodic flowering by the Arabidopsis GIGANTEA gene. , 1999, Science.

[113]  J. Peng,et al.  The Arabidopsis GAI gene defines a signaling pathway that negatively regulates gibberellin responses. , 1997, Genes & development.

[114]  T. Mizuno,et al.  Autoregulatory expression of the Escherichia coli hns gene encoding a nucleoid protein: H-NS functions as a repressor of its own transcription , 2004, Molecular and General Genetics MGG.

[115]  E. Huala,et al.  Blue-light photoreceptors in higher plants. , 1999, Annual review of cell and developmental biology.

[116]  J. Riechmann,et al.  Regulation of flowering in Arabidopsis by an FLC homologue. , 2001, Plant physiology.

[117]  M. Yanovsky,et al.  A quadruple photoreceptor mutant still keeps track of time , 2000, Current Biology.

[118]  G. Coupland,et al.  Analysis of flowering time control in Arabidopsis by comparison of double and triple mutants. , 2001, Plant physiology.

[119]  R. Amasino,et al.  Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time. , 2000, Science.

[120]  Z. Schwarz‐Sommer,et al.  Distinct roles of CONSTANS target genes in reproductive development of Arabidopsis. , 2000, Science.

[121]  S. Bird,et al.  The NADH dehydrogenase subunit 7 gene is interrupted by four group II introns in the wheat mitochondrial genome , 1994, Molecular and General Genetics MGG.

[122]  Allison K. Wilson,et al.  The VERNALIZATION 2 Gene Mediates the Epigenetic Regulation of Vernalization in Arabidopsis , 2001, Cell.

[123]  C. Dean,et al.  Arabidopsis mutants showing an altered response to vernalization. , 1996, The Plant journal : for cell and molecular biology.

[124]  M. Koornneef,et al.  Genetic control of light-inhibited hypocotyl elongation in Arabidopsis thaliana (L.) , 1980 .

[125]  P. Hedden,et al.  Modification of gibberellin production and plant development in Arabidopsis by sense and antisense expression of gibberellin 20-oxidase genes. , 1999, The Plant journal : for cell and molecular biology.

[126]  F. Madueño,et al.  Different roles of flowering-time genes in the activation of floral initiation genes in Arabidopsis. , 1997, The Plant cell.

[127]  Hongwei Guo,et al.  The Arabidopsis blue light receptor cryptochrome 2 is a nuclear protein regulated by a blue light-dependent post-transcriptional mechanism. , 1999, The Plant journal : for cell and molecular biology.

[128]  S. Jacobsen,et al.  SPINDLY, a tetratricopeptide repeat protein involved in gibberellin signal transduction in Arabidopsis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[129]  Joanna Putterill,et al.  The late elongated hypocotyl Mutation of Arabidopsis Disrupts Circadian Rhythms and the Photoperiodic Control of Flowering , 1998, Cell.

[130]  S. Prat,et al.  Gibberellins Signal Nuclear Import of PHOR1, a Photoperiod-Responsive Protein with Homology to Drosophila armadillo , 2001, Cell.

[131]  J Chory,et al.  The regulation of circadian period by phototransduction pathways in Arabidopsis , 1995, Science.

[132]  D. E. Somers,et al.  The short-period mutant, toc1-1, alters circadian clock regulation of multiple outputs throughout development in Arabidopsis thaliana. , 1998, Development.

[133]  A. Cashmore,et al.  Chimeric Proteins between cry1 and cry2 Arabidopsis Blue Light Photoreceptors Indicate Overlapping Functions and Varying Protein Stability , 1998, Plant Cell.

[134]  Hitoshi Onouchi,et al.  CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis , 2001, Nature.

[135]  N. Battey Aspects of seasonality. , 2000, Journal of experimental botany.

[136]  Steve A. Kay,et al.  Reciprocal Regulation Between TOC1 and LHY/CCA1 Within the Arabidopsis Circadian Clock , 2001, Science.

[137]  R. Yadegari,et al.  Mutations in the FIE and MEA Genes That Encode Interacting Polycomb Proteins Cause Parent-of-Origin Effects on Seed Development by Distinct Mechanisms , 2000, Plant Cell.

[138]  R. Amasino,et al.  FLOWERING LOCUS C Encodes a Novel MADS Domain Protein That Acts as a Repressor of Flowering , 1999, Plant Cell.

[139]  Chentao Lin Blue Light Receptors and Signal Transduction Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.000646. , 2002, The Plant Cell Online.

[140]  E. Finnegan,et al.  The molecular basis of vernalization: the central role of FLOWERING LOCUS C (FLC). , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[141]  M. Yano,et al.  Characterization and detection of epistatic interactions of 3 QTLs, Hd1, Hd2, and Hd3, controlling heading date in rice using nearly isogenic lines , 2000, Theoretical and Applied Genetics.

[142]  R. Amasino,et al.  Natural allelic variation identifies new genes in the Arabidopsis circadian system. , 1999, The Plant journal : for cell and molecular biology.

[143]  T. Sun,et al.  Synergistic derepression of gibberellin signaling by removing RGA and GAI function in Arabidopsis thaliana. , 2001, Genetics.

[144]  K. Apel,et al.  FPF1 modulates the competence to flowering in Arabidopsis. , 1999, The Plant journal : for cell and molecular biology.

[145]  D. Weigel,et al.  Integration of floral inductive signals in Arabidopsis , 2000, Nature.

[146]  R. N. Wilson,et al.  Gibberellin Is Required for Flowering in Arabidopsis thaliana under Short Days. , 1992, Plant physiology.

[147]  T. Moritz,et al.  The Arabidopsis Dwarf Mutant shi Exhibits Reduced Gibberellin Responses Conferred by Overexpression of a New Putative Zinc Finger Protein , 1999, Plant Cell.

[148]  L. Peña,et al.  Constitutive expression of Arabidopsis LEAFY or APETALA1 genes in citrus reduces their generation time , 2001, Nature Biotechnology.

[149]  M. Yano,et al.  Hd6, a rice quantitative trait locus involved in photoperiod sensitivity, encodes the α subunit of protein kinase CK2 , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[150]  T. Sun,et al.  Repressing a Repressor , 2001, The Plant Cell Online.

[151]  W. Peacock,et al.  DNA methylation and the promotion of flowering by vernalization. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[152]  K. Nakamura,et al.  Effects of sugar on vegetative development and floral transition in Arabidopsis. , 2001, Plant physiology.

[153]  J. Jeddeloh,et al.  Maintenance of genomic methylation requires a SWI2/SNF2-like protein , 1999, Nature Genetics.

[154]  A. Birve,et al.  Su(z)12, a novel Drosophila Polycomb group gene that is conserved in vertebrates and plants. , 2001, Development.

[155]  M. Yano,et al.  Hd1, a Major Photoperiod Sensitivity Quantitative Trait Locus in Rice, Is Closely Related to the Arabidopsis Flowering Time Gene CONSTANS , 2000, Plant Cell.

[156]  S. Hendricks,et al.  Photoperiodism in Plants. , 1960, Science.

[157]  A. Brice,et al.  A QTL for flowering time in Arabidopsis reveals a novel allele of CRY2 , 2002, Nature Genetics.

[158]  G. Coupland,et al.  Time measurement and the control of flowering in plants. , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

[159]  A. Millar,et al.  Independent action of ELF3 and phyB to control hypocotyl elongation and flowering time. , 2000, Plant physiology.

[160]  K. Shimamoto,et al.  Phytochromes confer the photoperiodic control of flowering in rice (a short-day plant). , 1999, The Plant journal : for cell and molecular biology.

[161]  M. Robertson,et al.  Identification of a Negative Regulator of Gibberellin Action, HvSPY, in Barley , 1998, Plant Cell.

[162]  D. E. Somers,et al.  Phytochromes and cryptochromes in the entrainment of the Arabidopsis circadian clock. , 1998, Science.

[163]  W. Peacock,et al.  Genes controlling fertilization-independent seed development in Arabidopsis thaliana. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[164]  M. Estelle,et al.  F-box proteins and protein degradation: An emerging theme in cellular regulation , 2000, Plant Molecular Biology.

[165]  A. Peeters,et al.  The GA5 locus of Arabidopsis thaliana encodes a multifunctional gibberellin 20-oxidase: molecular cloning and functional expression. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[166]  G. Bernier,et al.  Design in Arabidopsis thaliana of a synchronous system of floral induction by one long day. , 1996, The Plant journal : for cell and molecular biology.

[167]  G. Coupland,et al.  Functional importance of conserved domains in the flowering-time gene CONSTANS demonstrated by analysis of mutant alleles and transgenic plants. , 2002, The Plant journal : for cell and molecular biology.

[168]  C Robertson McClung,et al.  CIRCADIAN RHYTHMS IN PLANTS. , 2003, Annual review of plant physiology and plant molecular biology.

[169]  R. Simon,et al.  The CONSTANS gene of arabidopsis promotes flowering and encodes a protein showing similarities to zinc finger transcription factors , 1995, Cell.

[170]  M. Holdsworth,et al.  Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds. , 2000, The Plant journal : for cell and molecular biology.

[171]  R. Amasino,et al.  Fpa , a Gene Involved in Floral Induction in Arabidopsis, Encodes a Protein Containing Rna-recognition Motifs Overexpression of Fpa Results in Early-flowering in Short Days , 2001 .

[172]  M. Banfield,et al.  The structure of Antirrhinum centroradialis protein (CEN) suggests a role as a kinase regulator. , 2000, Journal of molecular biology.