Endorsement of alternative medicine and vaccine hesitancy among physicians: A cross-sectional study in four European countries

ABSTRACT Vaccine hesitancy has become a threat to public health, especially as it is a phenomenon that has also been observed among healthcare professionals. In this study, we analyzed the relationship between endorsement of complementary and alternative medicine (CAM) and vaccination attitudes and behaviors among healthcare professionals, using a cross-sectional sample of physicians with vaccination responsibilities from four European countries: Germany, Finland, Portugal, and France (total N = 2,787). Our results suggest that, in all the participating countries, CAM endorsement is associated with lower frequency of vaccine recommendation, lower self-vaccination rates, and being more open to patients delaying vaccination, with these relationships being mediated by distrust in vaccines. A latent profile analysis revealed that a profile characterized by higher-than-average CAM endorsement and lower-than-average confidence and recommendation of vaccines occurs, to some degree, among 19% of the total sample, although these percentages varied from one country to another: 23.72% in Germany, 17.83% in France, 9.77% in Finland, and 5.86% in Portugal. These results constitute a call to consider health care professionals’ attitudes toward CAM as a factor that could hinder the implementation of immunization campaigns.

[1]  Anna Soveri,et al.  International adaptation and validation of the Pro-VC-Be: measuring the psychosocial determinants of vaccine confidence in healthcare professionals in European countries , 2023, Expert review of vaccines.

[2]  Iryna Gurevych,et al.  A taxonomy of anti-vaccination arguments from a systematic literature review and text modelling , 2023, Nature Human Behaviour.

[3]  Thomas H. Costello,et al.  Psychological profiles of anti-vaccination argument endorsement , 2023, Scientific reports.

[4]  P. Giardullo,et al.  ‘We will multiply the fires of resistance’: The catalysts of dissent against institutional science and their interplay with refused knowledge communities , 2022, Public understanding of science.

[5]  Lukasz Stasielowicz A continuous time meta-analysis of the relationship between conspiracy beliefs and individual preventive behavior during the COVID-19 pandemic , 2022, Scientific Reports.

[6]  Isabell Koinig,et al.  The Effect of Science-Related Populism on Vaccination Attitudes and Decisions , 2022, Journal of Behavioral Medicine.

[7]  P. Verger,et al.  Vaccine hesitancy in health-care providers in Western countries: a narrative review , 2022, Expert review of vaccines.

[8]  Anna Soveri,et al.  An instrument to measure psychosocial determinants of health care professionals’ vaccination behavior: Validation of the Pro-VC-Be questionnaire , 2022, Expert review of vaccines.

[9]  I. Fronteira,et al.  Regulation of non-conventional therapies in Portugal: lessons learnt for strengthening human resources in health , 2021, Human Resources for Health.

[10]  O. Wilhelm,et al.  Measuring the 7Cs of Vaccination Readiness , 2021 .

[11]  Indrajeet Patil,et al.  performance: An R Package for Assessment, Comparison and Testing of Statistical Models , 2021, J. Open Source Softw..

[12]  D. Cameron "Imagine the Perfect Vaccine": Homeopathic Vaccine Alternatives and Vaccine Discourse in English Canada , 2021, Canadian bulletin of medical history = Bulletin canadien d'histoire de la medecine.

[13]  P. Verger,et al.  Vaccine Hesitancy, Acceptance, and Anti-Vaccination: Trends and Future Prospects for Public Health. , 2021, Annual review of public health.

[14]  S. Lewandowsky,et al.  Countering Misinformation and Fake News Through Inoculation and Prebunking , 2021, European Review of Social Psychology.

[15]  S. Lewandowsky,et al.  Unwillingness to engage in behaviors that protect against COVID-19: the role of conspiracy beliefs, trust, and endorsement of complementary and alternative medicine , 2020, BMC Public Health.

[16]  J. Raude,et al.  The role of alternative and complementary medical practices in vaccine hesitancy among nurses: a cross-sectional survey in Brittany. , 2020, Medecine et maladies infectieuses.

[17]  R. Recuero,et al.  Polarização, Hiperpartidarismo e Câmaras de Eco: Como circula a Desinformação sobre Covid-19 no Twitter , 2020, Revista Contracampo.

[18]  S. Lewandowsky,et al.  Trait reactance and trust in doctors as predictors of vaccination behavior, vaccine attitudes, and use of complementary and alternative medicine in parents of young children , 2020, PloS one.

[19]  M. Hornsey,et al.  Vaccine hesitancy is strongly associated with distrust of conventional medicine, and only weakly associated with trust in alternative medicine. , 2020, Social science & medicine.

[20]  G. Nunnari,et al.  Physician Attitudes and Perceptions of Complementary and Alternative Medicine (CAM): A Multicentre Italian Study , 2020, Frontiers in Oncology.

[21]  Jan K. Woike,et al.  Genesis or Evolution of Gender Differences? Worldview-Based Dilemmas in The Processing of Scientific Information , 2020, Journal of cognition.

[22]  L. Wong,et al.  Vaccine hesitancy and the resurgence of vaccine preventable diseases: the way forward for Malaysia, a Southeast Asian country , 2020, Human vaccines & immunotherapeutics.

[23]  A. Valiulis,et al.  Vaccine confidence among parents: Large scale study in eighteen European countries. , 2019, Vaccine.

[24]  Matthew S. Fritz,et al.  Mediation analysis. , 2019, Annual review of psychology.

[25]  M. Guay,et al.  Determinants of vaccine hesitancy in Quebec: a large population-based survey , 2019, Human vaccines & immunotherapeutics.

[26]  A. Y. Choi,et al.  Ten Frequently Asked Questions About Latent Class Analysis , 2018, Translational Issues in Psychological Science.

[27]  Joshua M. Rosenberg,et al.  tidyLPA: An R Package to Easily Carry Out Latent Profile Analysis (LPA) Using Open-Source or Commercial Software , 2018, J. Open Source Softw..

[28]  V. Mcgivney,et al.  The National Survey , 2018, European Dimensions and the Secondary School Curriculum.

[29]  M. Browne,et al.  Epistemic divides and ontological confusions: The psychology of vaccine scepticism , 2018, Human vaccines & immunotherapeutics.

[30]  C. Unsworth,et al.  Anti-vaccination and pro-CAM attitudes both reflect magical beliefs about health. , 2018, Vaccine.

[31]  J. Frawley,et al.  The associations between medical, allied and complementary medicine practitioner visits and childhood vaccine uptake. , 2018, Vaccine.

[32]  Per B. Brockhoff,et al.  lmerTest Package: Tests in Linear Mixed Effects Models , 2017 .

[33]  G. Rubin,et al.  A systematic review of factors affecting vaccine uptake in young children. , 2017, Vaccine.

[34]  T. Kemppainen,et al.  Use of complementary and alternative medicine in Europe: Health-related and sociodemographic determinants , 2017, Scandinavian journal of public health.

[35]  Cornelia Betsch,et al.  Barriers of Influenza Vaccination Intention and Behavior – A Systematic Review of Influenza Vaccine Hesitancy, 2005 – 2016 , 2017, PloS one.

[36]  H. Larson,et al.  Vaccine hesitancy and healthcare providers. , 2016, Vaccine.

[37]  R. Belue,et al.  Complementary and Alternative Medicine and Influenza Vaccine Uptake in US Children , 2016, Pediatrics.

[38]  S. Joos,et al.  Complementary and alternative medicine (CAM) as part of primary health care in Germany–comparison of patients consulting general practitioners and CAM practitioners: a cross-sectional study , 2016, BMC Complementary and Alternative Medicine.

[39]  J. Wardle,et al.  Complementary medicine and childhood immunisation: A critical review. , 2016, Vaccine.

[40]  J. Hwang,et al.  The Use of Complementary and Alternative Medicine by Korean Breast Cancer Women: Is It Associated with Severity of Symptoms? , 2015, Evidence-based complementary and alternative medicine : eCAM.

[41]  E. Sobo Social Cultivation of Vaccine Refusal and Delay among Waldorf (Steiner) School Parents. , 2015, Medical anthropology quarterly.

[42]  N. MacDonald Vaccine hesitancy: Definition, scope and determinants. , 2015, Vaccine.

[43]  J. Denollet,et al.  Theory of Planned Behavior , 2015 .

[44]  M. Rieder,et al.  'Nosodes' are no substitute for vaccines. , 2015, Paediatrics & child health.

[45]  K. Linde,et al.  Belief in and use of complementary therapies among family physicians, internists and orthopaedists in Germany - cross-sectional survey. , 2015, Family practice.

[46]  Jon Adams,et al.  Indirect and non-health risks associated with complementary and alternative medicine use: An integrative review , 2014 .

[47]  D. Bates,et al.  Fitting Linear Mixed-Effects Models Using lme4 , 2014, 1406.5823.

[48]  G. Parra,et al.  An introduction to latent variable mixture modeling (part 1): overview and cross-sectional latent class and latent profile analyses. , 2014, Journal of pediatric psychology.

[49]  S. Omer,et al.  Epidemiology of vaccine hesitancy in the United States , 2013, Human vaccines & immunotherapeutics.

[50]  È. Dubé,et al.  Vaccine hesitancy , 2013, Human vaccines & immunotherapeutics.

[51]  E. Ernst,et al.  Prevalence of use of complementary and alternative medicine (CAM) by physicians in the UK: a systematic review of surveys. , 2012, Clinical medicine.

[52]  H. Bedford,et al.  Communicating with parents about vaccination: a framework for health professionals , 2012, BMC Pediatrics.

[53]  M. Fagevik Olsén,et al.  Knowledge about complementary, alternative and integrative medicine (CAM) among registered health care providers in Swedish surgical care: a national survey among university hospitals , 2012, BMC Complementary and Alternative Medicine.

[54]  Andrew Ward,et al.  Personal use of complementary and alternative medicine (CAM) by U.S. health care workers. , 2012, Health services research.

[55]  M. Kerin,et al.  Complementary and alternative medicine use in oncology: A questionnaire survey of patients and health care professionals , 2011, BMC Cancer.

[56]  E. Ernst Anthroposophy: a risk factor for noncompliance with measles immunization. , 2011, The Pediatric infectious disease journal.

[57]  J. Szecsenyi,et al.  Integration of Complementary and Alternative Medicine into Family Practices in Germany: Results of a National Survey , 2010, Evidence-based complementary and alternative medicine : eCAM.

[58]  U. Heudorf,et al.  Heilpraktiker und öffentliches Gesundheitswesen , 2010, Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz.

[59]  E. Ernst Is reflexology an effective intervention? A systematic review of randomised controlled trials , 2009, The Medical journal of Australia.

[60]  M. Sewitch,et al.  A Literature Review of Health Care Professional Attitudes Toward Complementary and Alternative Medicine , 2008 .

[61]  John Launer Supervision , 2008, Postgraduate Medical Journal.

[62]  E. Ernst,et al.  A Systematic Review of Systematic Reviews of Spinal Manipulation , 2006, Journal of the Royal Society of Medicine.

[63]  Jonathan AC Sterne,et al.  Are the clinical effects of homoeopathy placebo effects? Comparative study of placebo-controlled trials of homoeopathy and allopathy , 2005, The Lancet.

[64]  B. Niggemann,et al.  Side‐effects of complementary and alternative medicine , 2003, Allergy.

[65]  M. Hyland,et al.  Developing a measure of attitudes: the holistic complementary and alternative medicine questionnaire. , 2003, Complementary therapies in medicine.

[66]  E. Ernst Rise in popularity of complementary and alternative medicine: reasons and consequences for vaccination. , 2001, Vaccine.

[67]  M. Lindeman,et al.  Assessment of Magical Beliefs about Food and Health , 2000, Journal of health psychology.

[68]  C. B. Colby The weirdest people in the world , 1973 .

[69]  THE WORLD HEALTH ORGANIZATION , 1954 .

[70]  J. Leask,et al.  "Do-it-yourself": Vaccine rejection and complementary and alternative medicine (CAM). , 2018, Social science & medicine.

[71]  S. Joos,et al.  Integration of Complementary and Alternative Medicine into Family Practices in Germany: Results of a , 2009 .

[72]  T. Kosonen THE FINNISH MEDICAL ASSOCIATION. , 1964, Laeknabladid.