High-Level CXCR4 Expression Correlates with Brain-Specific Metastasis of Non-Small Cell Lung Cancer

[1]  A. Silvani,et al.  CXCL12, CXCR4 and CXCR7 expression in brain metastases , 2009, Cancer biology & therapy.

[2]  A. Zlotnik New insights on the role of CXCR4 in cancer metastasis , 2008, The Journal of pathology.

[3]  R. Ransohoff,et al.  Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology , 2008, Progress in Neurobiology.

[4]  L. Helman,et al.  Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases , 2007, Clinical & Experimental Metastasis.

[5]  J. Posner,et al.  Brain metastases: epidemiology and pathophysiology , 2005, Journal of Neuro-Oncology.

[6]  Tae-Hee Lee,et al.  Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells. , 2004, Molecular cancer research : MCR.

[7]  F. André,et al.  Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome. , 2004, Annals of oncology : official journal of the European Society for Medical Oncology.

[8]  W. Rostène,et al.  Highly regionalized distribution of stromal cell‐derived factor‐1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons , 2003, The European journal of neuroscience.

[9]  G. Stamatoyannopoulos,et al.  Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. , 2003, Cancer research.

[10]  M. Burdick,et al.  The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. , 2003, American journal of respiratory and critical care medicine.

[11]  M. Ratajczak,et al.  CXCR4–SDF-1 Signalling, Locomotion, Chemotaxis and Adhesion , 2003, Journal of Molecular Histology.

[12]  T. Mcclanahan,et al.  Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.

[13]  Y Maruyama,et al.  A randomized trial of surgery in the treatment of single metastases to the brain. , 1990, The New England journal of medicine.

[14]  A. Zlotnik Involvement of chemokine receptors in organ-specific metastasis. , 2006, Contributions to microbiology.

[15]  A. Zlotnik,et al.  The biology of chemokines and their receptors. , 2000, Annual review of immunology.