Serum metabolome biomarkers associate low-level environmental perfluorinated compound exposure with oxidative /nitrosative stress in humans.
暂无分享,去创建一个
Heqing Shen | Weibing Zhang | Meiping Tian | Jie Zhang | Liangpo Liu | Qingyu Huang | Xiaofei Wang | Xiaoyan Du
[1] Heqing Shen,et al. Low-Level Environmental Phthalate Exposure Associates with Urine Metabolome Alteration in a Chinese Male Cohort. , 2016, Environmental science & technology.
[2] Romà Tauler,et al. Perfluoroalkylated Substance Effects in Xenopus laevis A6 Kidney Epithelial Cells Determined by ATR-FTIR Spectroscopy and Chemometric Analysis , 2016, Chemical research in toxicology.
[3] L. Groop,et al. α-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance , 2016, Diabetes Care.
[4] Samantha L. Hoopes,et al. Vascular actions of 20-HETE. , 2015, Prostaglandins & other lipid mediators.
[5] Heqing Shen,et al. Serum metabolomics reveals that arsenic exposure disrupted lipid and amino acid metabolism in rats: a step forward in understanding chronic arsenic toxicity. , 2015, Metallomics : integrated biometal science.
[6] Heqing Shen,et al. Urinary Metabolomics Revealed Arsenic Internal Dose-Related Metabolic Alterations: A Proof-of-Concept Study in a Chinese Male Cohort , 2014, Environmental science & technology.
[7] Heqing Shen,et al. Metabolomic analysis reveals a unique urinary pattern in normozoospermic infertile men. , 2014, Journal of proteome research.
[8] Yali Shi,et al. Highly elevated serum concentrations of perfluoroalkyl substances in fishery employees from Tangxun lake, china. , 2014, Environmental science & technology.
[9] Y. Lee,et al. Perfluoroalkyl acids in blood serum samples from children in Taiwan , 2014, Environmental Science and Pollution Research.
[10] Yifeng Zhang,et al. Serum levels of perfluoroalkyl acids (PFAAs) with isomer analysis and their associations with medical parameters in Chinese pregnant women. , 2014, Environment international.
[11] Siyuan Peng,et al. An integrated metabonomics and transcriptomics approach to understanding metabolic pathway disturbance induced by perfluorooctanoic acid. , 2013, Journal of pharmaceutical and biomedical analysis.
[12] Heqing Shen,et al. Perfluorooctanoic acid induces apoptosis through the p53-dependent mitochondrial pathway in human hepatic cells: a proteomic study. , 2013, Toxicology letters.
[13] C. Wong,et al. Blood plasma concentrations of endocrine disrupting chemicals in Hong Kong populations. , 2013, Journal of hazardous materials.
[14] A. Calafat,et al. Polyfluorinated compounds in dust from homes, offices, and vehicles as predictors of concentrations in office workers' serum. , 2013, Environment international.
[15] A. Shankar,et al. Positive association between perfluoroalkyl chemicals and hyperuricemia in children. , 2013, American journal of epidemiology.
[16] Jonathan W. Martin,et al. Isomers of perfluorooctanesulfonate and perfluorooctanoate and total perfluoroalkyl acids in human serum from two cities in North China. , 2013, Environment international.
[17] N. V. van Larebeke,et al. Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action , 2012, Journal of environmental and public health.
[18] Heqing Shen,et al. Perfluorooctanoic acid induces gene promoter hypermethylation of glutathione-S-transferase Pi in human liver L02 cells. , 2012, Toxicology.
[19] Heqing Shen,et al. Evaluation of cellular response to perfluorooctane sulfonate in human umbilical vein endothelial cells. , 2012, Toxicology in vitro : an international journal published in association with BIBRA.
[20] J. Domingo,et al. Health risks of dietary exposure to perfluorinated compounds. , 2012, Environment international.
[21] E. Mariussen. Neurotoxic effects of perfluoroalkylated compounds: mechanisms of action and environmental relevance , 2012, Archives of Toxicology.
[22] G. Luo,et al. Intrarenal metabolomics reveals the association of local organic toxins with the progression of diabetic kidney disease. , 2012, Journal of pharmaceutical and biomedical analysis.
[23] J. Atzrodt,et al. The synthesis of selected phase II metabolites – Ο-glucuronides and sulfates of drug development candidates , 2012 .
[24] Esben Budtz-Jørgensen,et al. Serum vaccine antibody concentrations in children exposed to perfluorinated compounds. , 2012, JAMA.
[25] S. Fenton,et al. Endocrine disrupting properties of perfluorooctanoic acid , 2011, The Journal of Steroid Biochemistry and Molecular Biology.
[26] Zi Yang,et al. Inhibition of nitric oxide synthase lowers fatty acid oxidation in preeclampsia-like mice at early gestational stage. , 2011, Chinese medical journal.
[27] Mark J. Strynar,et al. Polyfluorinated compounds: past, present, and future. , 2011, Environmental science & technology.
[28] J. F. Stevens,et al. Vitamins C and E: beneficial effects from a mechanistic perspective. , 2011, Free radical biology & medicine.
[29] B. Halliwell,et al. Artefacts in cell culture: α-Ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media. , 2011, Biochemical and biophysical research communications.
[30] C. Thomsen,et al. Levels in food and beverages and daily intake of perfluorinated compounds in Norway. , 2010, Chemosphere.
[31] Andrea Natali,et al. α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population , 2010, PloS one.
[32] T. Webster,et al. Exposure to Polyfluoroalkyl Chemicals and Cholesterol, Body Weight, and Insulin Resistance in the General U.S. Population , 2009, Environmental health perspectives.
[33] Kyle Steenland,et al. Association of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) with Uric Acid among Adults with Elevated Community Exposure to PFOA , 2009, Environmental health perspectives.
[34] J. Depierre,et al. High-dose, short-term exposure of mice to perfluorooctanesulfonate (PFOS) or perfluorooctanoate (PFOA) affects the number of circulating neutrophils differently, but enhances the inflammatory responses of macrophages to lipopolysaccharide (LPS) in a similar fashion. , 2009, Toxicology.
[35] J. Depierre,et al. The atrophy and changes in the cellular compositions of the thymus and spleen observed in mice subjected to short-term exposure to perfluorooctanesulfonate are high-dose phenomena mediated in part by peroxisome proliferator-activated receptor-alpha (PPARalpha). , 2009, Toxicology.
[36] Mark R. Viant,et al. Environmental metabolomics: a critical review and future perspectives , 2009, Metabolomics.
[37] D. Mozaffarian,et al. Omega-6 Fatty Acids and Risk for Cardiovascular Disease: A Science Advisory From the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention , 2009, Circulation.
[38] L. Sobrevia,et al. A hypothesis for preeclampsia: adenosine and inducible nitric oxide synthase in human placental microvascular endothelium. , 2008, Placenta.
[39] A. A. Jensen,et al. Emerging endocrine disrupters: perfluoroalkylated substances. , 2008, International journal of andrology.
[40] A Dick Vethaak,et al. Accumulation of perfluorooctane sulfonate (PFOS) in the food chain of the Western Scheldt estuary: Comparing field measurements with kinetic modeling. , 2008, Chemosphere.
[41] C. Lau,et al. Perfluoroalkyl acids: a review of monitoring and toxicological findings. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[42] B. van Ravenzwaay,et al. The use of metabolomics for the discovery of new biomarkers of effect. , 2007, Toxicology letters.
[43] M. Traber,et al. Vitamin E, antioxidant and nothing more. , 2007, Free radical biology & medicine.
[44] A. Koizumi,et al. Historical trends in human serum levels of perfluorooctanoate and perfluorooctane sulfonate in Shenyang, China. , 2007, The Tohoku journal of experimental medicine.
[45] K. Yu,et al. Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus). , 2007, Aquatic toxicology.
[46] K. Sasaki,et al. [Comparison of perfluorooctane sulfonate and perfluorooctane acid in serum of non-occupational human from Shenyang and Chongqing areas]. , 2006, Wei sheng yan jiu = Journal of hygiene research.
[47] L. Shaw,et al. Community Exposure to Perfluorooctanoate: Relationships Between Serum Concentrations and Exposure Sources , 2006, Journal of occupational and environmental medicine.
[48] Xiaofeng Yao,et al. Genotoxic risk and oxidative DNA damage in HepG2 cells exposed to perfluorooctanoic acid. , 2005, Mutation research.
[49] S. Tyagi,et al. Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle , 2004, Nutrition & metabolism.
[50] R. Feinman,et al. What is Nutrition & Metabolism? , 2004, Nutrition & Metabolism.
[51] C. Lau,et al. The developmental toxicity of perfluoroalkyl acids and their derivatives. , 2004, Toxicology and applied pharmacology.
[52] M. Roberfroid,et al. Peroxisomal Enzymes and 8-Hydroxydeoxyguanosine in Rat Liver Treated with Perfluorooctanoic Acid , 2004, Disease markers.
[53] R. Henning,et al. Protective role of endothelial nitric oxide synthase , 2003, The Journal of pathology.
[54] D. Madge,et al. Synthesis and analysis of conjugates of the major vitamin E metabolite, α-CEHC , 2002 .
[55] R. Parker,et al. Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status. , 2002, The Journal of biological chemistry.
[56] Qiang Yang,et al. Further evidence for the involvement of inhibition of cell proliferation and development in thymic and splenic atrophy induced by the peroxisome proliferator perfluoroctanoic acid in mice. , 2001, Biochemical pharmacology.
[57] D. Grandér,et al. Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid. , 2001, Toxicology and applied pharmacology.
[58] J. Giesy,et al. Global distribution of perfluorooctane sulfonate in wildlife. , 2001, Environmental science & technology.
[59] J. Depierre,et al. Effects of peroxisome proliferators on the thymus and spleen of mice , 2000, Clinical and experimental immunology.
[60] J. Lindon,et al. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. , 1999, Xenobiotica; the fate of foreign compounds in biological systems.
[61] N. Weintraub,et al. Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation. , 1998, Circulation research.
[62] James B. Mitchell,et al. The multifaceted roles of nitric oxide in cancer. , 1998, Carcinogenesis.
[63] T. Yamazaki,et al. 15-lipoxygenase metabolite(s) of arachidonic acid mediates adrenocorticotropin action in bovine adrenal steroidogenesis. , 1996, Endocrinology.
[64] G. J. Van Der Kraak,et al. Mechanisms of action of free arachidonic acid on ovarian steroid production in the goldfish. , 1996, General and comparative endocrinology.
[65] M. Mcdaniel,et al. Aminoguanidine, a Novel Inhibitor of Nitric Oxide Formation, Prevents Diabetic Vascular Dysfunction , 1992, Diabetes.
[66] A. Peitzman,et al. Nitrogen oxide levels in patients after trauma and during sepsis. , 1991, Annals of surgery.
[67] P. Proctor. Similar Functions of Uric Acid and Ascorbate in Man ? , 1970, Nature.
[68] Heqing Shen,et al. Online background cleanup followed by high-performance liquid chromatography with tandem mass spectrometry for the analysis of perfluorinated compounds in human blood. , 2015, Journal of separation science.
[69] A. Angerhofer,et al. Uric Acid and Oxidative Stress , 2011 .
[70] Paul D Jones,et al. Gene expression profiles in rat liver treated with perfluorooctanoic acid (PFOA). , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[71] T Tsutsui,et al. Airborne Perfluorooctanoate May Be a Substantial Source Contamination in Kyoto Area, Japan , 2005, Bulletin of environmental contamination and toxicology.