论文信息 - PHYTOCHEMICAL INVESTIGATION AND COMPARATIVE ANTHELMINTIC ACTIVITY OF BETWEEN METHANOL AND ACETONE EXTRACT OF LIMONIA ACIDISSIMA L (FRUIT PEEL)

PHYTOCHEMICAL INVESTIGATION AND COMPARATIVE ANTHELMINTIC ACTIVITY OF BETWEEN METHANOL AND ACETONE EXTRACT OF LIMONIA ACIDISSIMA L (FRUIT PEEL)

Limonia acidissima L. is the gathering of Rutaceae (Citrus family) which has a spot with the monotypic assortment Limonia, limited to Southeast Asia. It is locally familiar as kath bel. It is used widely as a folk medicine for several severe diseases such as heartburn, fart, loose bowels, diarrhea and hemorrhoids. For anthelmintic activity, methanolic and acetonic fruit peels extracts of Limonia acidissima L. was investigated for their action against Paramphistomum cervi. Different doses of each extract were examined in the bioassay, which included assurance of time of paralysis and time of death of the worms. The reference standard albendazole showed paralysis time 13.4 minutes and death time 18.4 minutes. On the other hand, methanolic and acetonic extracts showed at doses 150 mg/ml significant effect which has paralysis time 19.6 and 24.4 minutes, death time 21.6 and 26.6 minutes; respectively.

[1] K. Jha,et al. In-Vitro Anthelmintic Activity of Luffa cylindrica Leaves in Indian Adult Earthworm , 2012 .

[2] Mei Sun,et al. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer , 2004, Life Sciences.

[3] P. Abdu,et al. In vitro screening of two Nigerian medicinal plants (Vernonia amygdalina and Annona senegalensis) for anthelmintic activity. , 2003, Veterinary parasitology.

[4] S. G. Leitão,et al. Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method , 2001, Phytotherapy research : PTR.

[5] B. D. Oomah,et al. Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products , 1998 .

[6] K. Wong,et al. Volatile Constituents of Averrhoa bilimbi L. Fruit , 1995 .

[7] K. Daniel. Investigation of Anthelmintic Activity of Withania somnifera , 2012 .

[8] S. Wahab,et al. In-vitro anthelmintic activity of Coleus aromaticus root in Indian Adult Earthworm , 2012 .

[9] Sucheta Gaikwad,et al. Anthelmintic activity of Cassia auriculata L. extracts-In vitro study , 2011 .

[10] S. Shukla,et al. A report on anthelmintic activity of Cassia tora leaves , 2009 .

[11] L. Nahar,et al. Antibacterial, Cytotoxic and Antioxidant Activity of Crude Extract of Marsilea Quadrifolia , 2009 .

[12] C. Khare,et al. Indian Medicinal Plants: An Illustrated Dictionary , 2007 .