Design of CMOS Two-stage Operational Amplifier for ECG Monitoring System Using 90nm Technology

This paper presents a high performance Two-stage operational amplifier for biomedical applications. This Two-stage is designed for low noise, low power, high PSRR and high CMRR. The Miller compensation technique (Cc) is used with a nulling active resistance (Rz) implemented using Transmission gate transistors for stable operation in feedback mode. The operational amplifier was manufactured in a SPECTRE using GPDK 0.90-um CMOS technology with threshold voltages of a 0.17 V and - 0.14 V achieve a low power 2.6uW, high CMRR up to 130dB and PSRR up to 70dB at 1V power supply.

[2]  R.H. Dennard,et al.  1 µm MOSFET VLSI technology: Part IV—Hot-electron design constraints , 1979, IEEE Transactions on Electron Devices.

[3]  A. Neviani,et al.  A 1µA front-end for pacemaker atrial sensing channels , 2001 .

[4]  D.B. Popovic,et al.  Sensory nerve recording for closed-loop control to restore motor functions , 1993, IEEE Transactions on Biomedical Engineering.

[5]  Phillip E Allen,et al.  CMOS Analog Circuit Design , 1987 .

[6]  Wei-Song Wang,et al.  Low-Power Instrumental Amplifier for Portable ECG , 2009, 2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis.

[7]  Yong Ching Lim,et al.  A low-voltage CMOS OTA with rail-to-rail differential input range , 2000 .

[8]  Andrea Baschirotto,et al.  A 1-/spl mu/A front end for pacemaker atrial sensing channels with early sensing capability , 2003, IEEE Transactions on Circuits and Systems II: Analog and Digital Signal Processing.

[9]  Feng Wan,et al.  A 90nm CMOS bio-potential signal readout front-end with improved powerline interference rejection , 2009, 2009 IEEE International Symposium on Circuits and Systems.

[10]  Sebastian Ehrlichmann Vlsi Design Techniques For Analog And Digital Circuits , 2016 .

[11]  Mohamad Sawan,et al.  CMOS Front-end Amplifier Dedicated to Monitor Very Low Amplitude Signal from Implantable Sensors , 2000 .

[12]  R. Stein,et al.  Principles Underlying New Methods for Chronic Neural Recording , 1975, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[13]  Chin-Teng Lin,et al.  Front-end amplifier of low-noise and tunable BW/gain for portable biomedical signal acquisition , 2008, 2008 IEEE International Symposium on Circuits and Systems.

[14]  R.G. Carvajal,et al.  A Low-Voltage Low-Power Front-End for Wearable EEG Systems , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[15]  M Sawan,et al.  Implantable volume monitor and miniaturized stimulator dedicated to bladder control. , 1997, Artificial organs.

[16]  Hwang-Cherng Chow,et al.  A High Performance Current-Mode Instrumentation Amplifier with Level Shifter for Single Power Biomedical Applications , 2014 .

[17]  Ken Cai,et al.  A Zigbee Based Mesh Network for ECG Monitoring System , 2010, 2010 4th International Conference on Bioinformatics and Biomedical Engineering.

[18]  John G. Webster,et al.  Medical Instrumentation: Application and Design , 1997 .

[19]  E. J. Kennedy Operational amplifier circuits : theory and applications , 1988 .

[20]  Y.F. Low,et al.  Development of PC-Based ECG Monitoring System , 2006, 2006 4th Student Conference on Research and Development.

[21]  D. Schroeder,et al.  An Ultra Low-Noise CMOS Operational Amplifier with Programmable Noise-Power Trade-Off , 2006, 2006 Proceedings of the 32nd European Solid-State Circuits Conference.