Predictive Biomarkers as a Guide to Future Therapy Selection in Melanoma
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[1] R. Sullivan,et al. A single center experience with high-dose (HD) IL-2 treatment for patients with advanced melanoma and pilot investigation of a novel gene expression signature as a predictor of response. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[2] G. Linette,et al. Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104) , 2012, Journal of Translational Medicine.
[3] S. Nelson,et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation , 2010, Nature.
[4] V. Sondak,et al. Melanoma--an unlikely poster child for personalized cancer therapy. , 2010, The New England journal of medicine.
[5] K. Flaherty,et al. Inhibition of mutated, activated BRAF in metastatic melanoma. , 2010, The New England journal of medicine.
[6] T. Gajewski,et al. Gene Signature in Melanoma Associated With Clinical Activity: A Potential Clue to Unlock Cancer Immunotherapy , 2010, Cancer journal.
[7] Soonmyung Paik,et al. Gene-expression-based prognostic assays for breast cancer , 2010, Nature Reviews Clinical Oncology.
[8] David C. Smith,et al. Safety and antitumor activity of biweekly MDX-1106 (Anti-PD-1, BMS-936558/ONO-4538) in patients with advanced refractory malignancies. , 2010 .
[9] K. Flaherty,et al. Final results of E2603: A double-blind, randomized phase III trial comparing carboplatin (C)/paclitaxel (P) with or without sorafenib (S) in metastatic melanoma. , 2010 .
[10] A. Tolcher,et al. A phase I study of RO4929097, a novel gamma secretase inhibitor, in patients with advanced solid tumors. , 2010 .
[11] Qian Wang,et al. Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity. , 2010, Blood.
[12] A. Tolcher,et al. Castration-resistant prostate cancer--hormone therapy redux. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] R. Gutzmer,et al. Anal Mucosal Melanoma with KIT-Activating Mutation and Response to Imatinib Therapy – Case Report and Review of the Literature , 2009, Dermatology.
[14] Jimmy Lin,et al. Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4 , 2009, Nature Genetics.
[15] R. Vonderheide,et al. Clinical Use of Anti‐CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells , 2009, Annals of the New York Academy of Sciences.
[16] T. Gajewski,et al. PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model. , 2009, Blood.
[17] F. Marincola,et al. Serum vascular endothelial growth factor and fibronectin predict clinical response to high-dose interleukin-2 therapy. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[18] J. Kirkwood,et al. Prediction of response to alkylator-based chemotherapy in metastatic melanoma (MM) using gene expression and promoter methylation signatures. , 2009, Journal of Clinical Oncology.
[19] S. Chasalow,et al. Association of baseline and on-study tumor biopsy markers with clinical activity in patients (pts) with advanced melanoma treated with ipilimumab. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[20] G. Schuler,et al. Association of gene expression profile in metastatic melanoma and survival to a dendritic cell-based vaccine. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[21] M. Tretiakova,et al. Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment. , 2009, Cancer research.
[22] V. Sondak,et al. Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Grou , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[23] R. Gutzmer,et al. Analysis of c-KIT expression and KIT gene mutation in human mucosal melanomas , 2008, British Journal of Cancer.
[24] Susan Muller,et al. KIT Gene Mutations and Copy Number in Melanoma Subtypes , 2008, Clinical Cancer Research.
[25] M. Ross,et al. Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib , 2008, Nature Clinical Practice Oncology.
[26] M. Ross,et al. Phase II trial of imatinib mesylate in patients with metastatic melanoma , 2008, British Journal of Cancer.
[27] D. Elder,et al. A Phase I Trial of the Oral, Multikinase Inhibitor Sorafenib in Combination with Carboplatin and Paclitaxel , 2008, Clinical Cancer Research.
[28] B. Bastian,et al. Dose‐dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation , 2008, Pigment cell & melanoma research.
[29] Hua Yu,et al. Activated stat-3 in melanoma. , 2008, Cancer control : journal of the Moffitt Cancer Center.
[30] Jamila Louahed,et al. Association of gene expression signature and clinical efficacy of MAGE-A3 antigen-specific cancer immunotherapeutic (ASCI) as adjuvant therapy in resected stage IB/II non-small cell lung cancer (NSCLC) , 2008 .
[31] D. Schadendorf,et al. Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy , 2008, Cancer Immunology, Immunotherapy.
[32] A. D. Van den Abbeele,et al. Major response to imatinib mesylate in KIT-mutated melanoma. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[33] K. McMasters,et al. Transient T cell depletion causes regression of melanoma metastases , 2008, Journal of Translational Medicine.
[34] T. Gajewski. Failure at the Effector Phase: Immune Barriers at the Level of the Melanoma Tumor Microenvironment , 2007, Clinical Cancer Research.
[35] T. Gajewski,et al. Chemokines expressed in melanoma metastases associated with T cell infiltration , 2007 .
[36] D. Germano,et al. Lapatinib in breast cancer. , 2007, Annals of Oncology.
[37] R. Salgia,et al. c-Met Is a Potentially New Therapeutic Target for Treatment of Human Melanoma , 2007, Clinical Cancer Research.
[38] C. Blank,et al. Homeostatic Proliferation as an Isolated Variable Reverses CD8+ T Cell Anergy and Promotes Tumor Rejection1 , 2006, The Journal of Immunology.
[39] M. Ratain,et al. Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis , 2006, British Journal of Cancer.
[40] V. Appay,et al. New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site1 , 2006, The Journal of Immunology.
[41] D. Pinkel,et al. PI3-kinase subunits are infrequent somatic targets in melanoma. , 2006, The Journal of investigative dermatology.
[42] Susan O'Brien,et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. , 2006, The New England journal of medicine.
[43] M. Atkins,et al. Multicenter Phase II trial of high‐dose imatinib mesylate in metastatic melanoma , 2006, Cancer.
[44] A. Bardia,et al. Hand-foot syndrome after dose-dense adjuvant chemotherapy for breast cancer: a case series. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[45] T. Gajewski,et al. Tumor progression despite massive influx of activated CD8+ T cells in a patient with malignant melanoma ascites , 2006, Cancer Immunology, Immunotherapy.
[46] D. Massi,et al. Evidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma , 2006, Modern Pathology.
[47] E. Gilboa,et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. , 2005, The Journal of clinical investigation.
[48] J. Fridlyand,et al. Distinct sets of genetic alterations in melanoma. , 2005, The New England journal of medicine.
[49] S. Steinberg,et al. Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma , 2005, The Journal of Immunology.
[50] J. Sosman,et al. Phase II Trial of the O6-Alkylguanine DNA Alkyltransferase Inhibitor O6-Benzylguanine and 1,3-Bis(2-Chloroethyl)-1-Nitrosourea in Advanced Melanoma , 2005, Clinical Cancer Research.
[51] G. Prendergast,et al. Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors , 2005, Expert opinion on therapeutic targets.
[52] Hua Yu,et al. Stat3 Activity in Melanoma Cells Affects Migration of Immune Effector Cells and Nitric Oxide-Mediated Antitumor Effects1 , 2005, The Journal of Immunology.
[53] R. Mirimanoff,et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. , 2005, The New England journal of medicine.
[54] S. Rosenberg,et al. Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[55] Ping Chen,et al. Overriding Imatinib Resistance with a Novel ABL Kinase Inhibitor , 2004, Science.
[56] A. Mackensen,et al. Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. , 2004, Cancer research.
[57] Tasuku Honjo,et al. PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T Cells , 2004, Cancer Research.
[58] A. D. Van den Abbeele,et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[59] C. Uyttenhove,et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase , 2003, Nature Medicine.
[60] N. Cascinelli,et al. Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma. , 2003, Cancer research.
[61] Lieping Chen,et al. B7-H1 pathway and its role in the evasion of tumor immunity , 2003, Journal of Molecular Medicine.
[62] R. Schwartz. T cell anergy. , 2003, Annual review of immunology.
[63] A. Nicholson,et al. Mutations of the BRAF gene in human cancer , 2002, Nature.
[64] T. Schumacher,et al. Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses , 2001, The Journal of experimental medicine.
[65] P. Coulie,et al. A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3 , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[66] C. Eng,et al. Epigenetic PTEN silencing in malignant melanomas without PTEN mutation. , 2000, The American journal of pathology.
[67] M. Peacocke,et al. Identification of PTEN mutations in metastatic melanoma specimens , 2000, Journal of medical genetics.
[68] D. Munn,et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. , 1998, Science.
[69] N. Vogelzang,et al. Effective chemotherapy for melanoma after treatment with interleukin‐2 , 1992, Cancer.
[70] L. Larue,et al. The WNT/Beta-catenin pathway in melanoma. , 2006, Frontiers in bioscience : a journal and virtual library.
[71] T. Nomura,et al. Naturally arising CD25+CD4+ regulatory T cells in tumor immunity. , 2005, Current topics in microbiology and immunology.