Phosphorylation of RACK 1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase *

Patrick A. Kiely, George S. Baillie, Robert Barrett, Deirdre A. Buckley, David R. Adams, Miles D. Houslay, and Rosemary O’Connor From the Cell Biology Laboratory, Department of Biochemistry, BioSciences Institute, University College Cork, Cork, Ireland, the Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, United Kingdom, and the Department of Chemistry, Heriot-Watt University, Riccarton Campus, Edinburgh EH14AS, Scotland, United Kingdom