Eukaryotic DNA Replication Origins Reconciling Disparate Data

[1]  M. Calos,et al.  Autonomous replication in Drosophila melanogaster tissue culture cells , 1995, Chromosoma.

[2]  Aaron Bensimon,et al.  Dynamics of DNA Replication in Mammalian Somatic Cells Nucleotide Pool Modulates Origin Choice and Interorigin Spacing , 2003, Cell.

[3]  M. DePamphilis,et al.  Xenopus origin recognition complex (ORC) initiates DNA replication preferentially at sequences targeted by Schizosaccharomyces pombe ORC , 2003, The EMBO journal.

[4]  M. Prioleau,et al.  Replication of the Chicken β-Globin Locus: Early-Firing Origins at the 5′ HS4 Insulator and the ρ- and βA-Globin Genes Show Opposite Epigenetic Modifications , 2003, Molecular and Cellular Biology.

[5]  Tatsuro S. Takahashi,et al.  Multiple ORC‐binding sites are required for efficient MCM loading and origin firing in fission yeast , 2003, The EMBO journal.

[6]  M. Botchan,et al.  Role for a Drosophila Myb-containing protein complex in site-specific DNA replication , 2002, Nature.

[7]  M. DePamphilis,et al.  Site‐specific ORC binding, pre‐replication complex assembly and DNA synthesis at Schizosaccharomyces pombe replication origins , 2002, The EMBO journal.

[8]  Anindya Dutta,et al.  DNA replication in eukaryotic cells. , 2002, Annual review of biochemistry.

[9]  B. Tye,et al.  The Hexameric Eukaryotic MCM Helicase: Building Symmetry from Nonidentical Parts* , 2000, The Journal of Biological Chemistry.

[10]  D. Natale,et al.  Initiation of eukaryotic DNA replication: conservative or liberal? , 2000, Journal of cellular physiology.

[11]  I. Royzman,et al.  Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts. , 2000, Genes & development.

[12]  B. Stillman,et al.  Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro. , 2000, Genes & development.

[13]  N. Heintz,et al.  Premature Structural Changes at Replication Origins in a Yeast Minichromosome Maintenance (MCM) Mutant* , 2000, The Journal of Biological Chemistry.

[14]  P. Jares,et al.  Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading. , 2000, Genes & development.

[15]  M. Giacca,et al.  Selection of homeotic proteins for binding to a human DNA replication origin. , 2000, Journal of molecular biology.

[16]  Z. Dong,et al.  Major DNA replication initiation sites in the c‐myc locus in human cells , 2000, Journal of cellular biochemistry.

[17]  J. Diffley,et al.  Uninterrupted MCM2-7 function required for DNA replication fork progression. , 2000, Science.

[18]  D. Natale,et al.  Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M–G1 transition in mammals , 2000, The EMBO journal.

[19]  J. Diffley,et al.  DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p , 2000, The EMBO journal.

[20]  Bruce Stillman,et al.  Assembly of a Complex Containing Cdc45p, Replication Protein A, and Mcm2p at Replication Origins Controlled by S-Phase Cyclin-Dependent Kinases and Cdc7p-Dbf4p Kinase , 2000, Molecular and Cellular Biology.

[21]  M. Lei,et al.  Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. , 2000, Genes & development.

[22]  J. Moreau,et al.  XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis , 2000, Nature.

[23]  Zoi Lygerou,et al.  The Cdt1 protein is required to license DNA for replication in fission yeast , 2000, Nature.

[24]  Hiroyuki Araki,et al.  Dpb11 Controls the Association between DNA Polymerases α and ɛ and the Autonomously Replicating Sequence Region of Budding Yeast , 2000, Molecular and Cellular Biology.

[25]  M. Giacca,et al.  Start sites of bidirectional DNA synthesis at the human lamin B2 origin. , 2000, Science.

[26]  B. Stillman,et al.  A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[27]  J. Diffley,et al.  CDK inactivation is the only essential function of the APC/C and the mitotic exit network proteins for origin resetting during mitosis. , 2000, Molecular cell.

[28]  Z. Kelman,et al.  The single minichromosome maintenance protein of Methanobacterium thermoautotrophicum DeltaH contains DNA helicase activity. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Z. You,et al.  Biochemical Analysis of the Intrinsic Mcm4-Mcm6-Mcm7 DNA Helicase Activity , 1999, Molecular and Cellular Biology.

[30]  S. Bell,et al.  Drosophila ORC specifically binds to ACE3, an origin of DNA replication control element. , 1999, Genes & development.

[31]  F. Antequera,et al.  Organization of DNA replication origins in the fission yeast genome , 1999, The EMBO journal.

[32]  H. Masukata,et al.  Clustered Adenine/Thymine Stretches Are Essential for Function of a Fission Yeast Replication Origin , 1999, Molecular and Cellular Biology.

[33]  J. Tower,et al.  The Drosophila chiffon gene is required for chorion gene amplification, and is related to the yeast Dbf4 regulator of DNA replication and cell cycle. , 1999, Development.

[34]  Tatsuro S. Takahashi,et al.  Association of Fission Yeast Orp1 and Mcm6 Proteins with Chromosomal Replication Origins , 1999, Molecular and Cellular Biology.

[35]  O. Aparicio,et al.  Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[36]  M. Leffak,et al.  Activity of the c-myc Replicator at an Ectopic Chromosomal Location , 1999, Molecular and Cellular Biology.

[37]  J. Huberman.  Genetic methods for characterizing the cis-acting components of yeast DNA replication origins. , 1999, Methods.

[38]  A. Spradling,et al.  Chorion gene amplification in Drosophila: A model for metazoan origins of DNA replication and S-phase control. , 1999, Methods.

[39]  J. Blow,et al.  Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins. , 1999, Journal of cell science.

[40]  S. Bell,et al.  ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. , 1999, Genes & development.

[41]  S. Gerbi,et al.  Chromosomal ARS1 has a single leading strand start site. , 1999, Molecular cell.

[42]  R. Chuang,et al.  The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[43]  A. Lépingle,et al.  Short DNA fragments without sequence similarity are initiation sites for replication in the chromosome of the yeast Yarrowia lipolytica. , 1999, Molecular biology of the cell.

[44]  J. Blow,et al.  The regulation of replication origin activation. , 1999, Current opinion in genetics & development.

[45]  B. Stillman,et al.  The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[46]  M. DePamphilis.  Replication origins in metazoan chromosomes: fact or fiction? , 1999, BioEssays : news and reviews in molecular, cellular and developmental biology.

[47]  F. Urnov,et al.  Methods to map origins of replication in eukaryotes , 1999 .

[48]  J. Leatherwood.  Emerging mechanisms of eukaryotic DNA replication initiation. , 1998, Current opinion in cell biology.

[49]  J. Diffley.  Replication control: Choreographing replication origins , 1998, Current Biology.

[50]  D. Landsman,et al.  AT-hook motifs identified in a wide variety of DNA-binding proteins. , 1998, Nucleic acids research.

[51]  R. Laskey,et al.  Human Minichromosome Maintenance Proteins and Human Origin Recognition Complex 2 Protein on Chromatin* , 1998, The Journal of Biological Chemistry.

[52]  G. Wahl,et al.  Genetic dissection of a mammalian replicator in the human beta-globin locus. , 1998, Science.

[53]  J. Diffley,et al.  Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders. , 1998, Molecular cell.

[54]  M. DePamphilis,et al.  Identification of Primary Initiation Sites for DNA Replication in the Hamster Dihydrofolate Reductase Gene Initiation Zone , 1998, Molecular and Cellular Biology.

[55]  M. Giacca,et al.  Cell cycle modulation of protein–DNA interactions at a human replication origin , 1998, The EMBO journal.

[56]  B. Stillman,et al.  Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. , 1998, Science.

[57]  D. Gilbert,et al.  Replication origins in yeast versus metazoa: separation of the haves and the have nots. , 1998, Current opinion in genetics & development.

[58]  A. Spradling,et al.  Cell cycle control of chorion gene amplification. , 1998, Genes & development.

[59]  W. L. Fangman,et al.  Cdc7 is required throughout the yeast S phase to activate replication origins. , 1998, Genes & development.

[60]  J. Diffley,et al.  The Cdc7 protein kinase is required for origin firing during S phase. , 1998, Genes & development.

[61]  J. Newport,et al.  Identification of a Preinitiation Step in DNA Replication That Is Independent of Origin Recognition Complex and cdc6, but Dependent on cdk2 , 1998, The Journal of cell biology.

[62]  S. Gerbi,et al.  Discrete start sites for DNA synthesis in the yeast ARS1 origin. , 1998, Science.

[63]  B. Stillman,et al.  Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. , 1997, Genes & development.

[64]  C. Newlon.  Putting It All Together: Building a Prereplicative Complex , 1997, Cell.

[65]  S. Bell,et al.  Architecture of the yeast origin recognition complex bound to origins of DNA replication , 1997, Molecular and cellular biology.

[66]  S. Gerbi,et al.  Replication initiation point mapping. , 1997, Methods.

[67]  M. Giacca,et al.  Mapping replication origins by quantifying relative abundance of nascent DNA strands using competitive polymerase chain reaction. , 1997, Methods.

[68]  J. Huberman.  Mapping replication origins, pause sites, and termini by neutral/alkaline two-dimensional gel electrophoresis. , 1997, Methods.

[69]  S. Lin,et al.  Functional equivalency and diversity of cis-acting elements among yeast replication origins , 1997, Molecular and cellular biology.

[70]  K. Nasmyth,et al.  Loading of an Mcm Protein onto DNA Replication Origins Is Regulated by Cdc6p and CDKs , 1997, Cell.

[71]  D. Gilbert,et al.  The replication origin decision point is a mitogen-independent, 2-aminopurine-sensitive, G1-phase event that precedes restriction point control , 1997, Molecular and cellular biology.

[72]  L. Drury,et al.  Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[73]  A. Spradling,et al.  The k43 gene, required for chorion gene amplification and diploid cell chromosome replication, encodes the Drosophila homolog of yeast origin recognition complex subunit 2. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[74]  S. Bell,et al.  Coordinate Binding of ATP and Origin DNA Regulates the ATPase Activity of the Origin Recognition Complex , 1997, Cell.

[75]  S. Bell,et al.  Initiation of DNA replication in eukaryotic cells. , 1997, Annual review of cell and developmental biology.

[76]  K. Nasmyth.  At the heart of the budding yeast cell cycle. , 1996, Trends in genetics : TIG.

[77]  D. Nathans,et al.  Multivalent DNA-binding properties of the HMG-1 proteins. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[78]  D. Gilbert,et al.  A Distinct G1 Step Required to Specify the Chinese Hamster DHFR Replication Origin , 1996, Science.

[79]  M. Giacca,et al.  In vivo protein-DNA interactions at human DNA replication origin. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[80]  W. Dunphy,et al.  Role for a Xenopus Orc2-related protein in controlling DNA replication , 1996, Nature.

[81]  D. Kowalski,et al.  Multiple DNA elements in ARS305 determine replication origin activity in a yeast chromosome. , 1996, Nucleic acids research.

[82]  T. Kelly,et al.  Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[83]  T. Kelly,et al.  Genetic analysis of an ARS element from the fission yeast Schizosaccharomyces pombe. , 1995, The EMBO journal.

[84]  S. Bell,et al.  The multidomain structure of Orc1 p reveals similarity to regulators of DNA replication and transcriptional silencing , 1995, Cell.

[85]  P. Dijkwel,et al.  On the nature of replication origins in higher eukaryotes. , 1995, Current opinion in genetics & development.

[86]  M. DePamphilis.  [47] Specific labeling of newly replicated DNA , 1995 .

[87]  B. Stillman,et al.  Functional conservation of multiple elements in yeast chromosomal replicators , 1994, Molecular and cellular biology.

[88]  C. Newlon,et al.  Domain B of ARS307 contains two functional elements and contributes to chromosomal replication origin function , 1994, Molecular and cellular biology.

[89]  J. Diffley,et al.  Two steps in the assembly of complexes at yeast replication origins in vivo , 1994, Cell.

[90]  L. Zentilin,et al.  Fine mapping of a replication origin of human DNA. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[91]  S. Gerbi,et al.  Analysis of an origin of DNA amplification in Sciara coprophila by a novel three-dimensional gel method , 1994, Molecular and cellular biology.

[92]  D. Beach,et al.  cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis. , 1994, The EMBO journal.

[93]  R A Laskey,et al.  Regulation of eukaryotic DNA replication. , 1994, Annual review of biochemistry.

[94]  D Kowalski,et al.  A DNA unwinding element and an ARS consensus comprise a replication origin within a yeast chromosome. , 1993, The EMBO journal.

[95]  C. Newlon,et al.  The structure and function of yeast ARS elements. , 1993, Current opinion in genetics & development.

[96]  T. Nethanel,et al.  Assembly of simian virus 40 Okazaki pieces from DNA primers is reversibly arrested by ATP depletion , 1992, Journal of virology.

[97]  J. Diffley,et al.  Protein-DNA interactions at a yeast replication origin , 1992, Nature.

[98]  Bruce Stillman,et al.  ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex , 1992, Nature.

[99]  B. Stillman,et al.  A yeast chromosomal origin of DNA replication defined by multiple functional elements. , 1992, Science.

[100]  M. DePamphilis,et al.  Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregation. , 1991, The EMBO journal.

[101]  W. L. Fangman,et al.  Mapping replication origins in yeast chromosomes , 1991, BioEssays : news and reviews in molecular, cellular and developmental biology.

[102]  T. Nethanel,et al.  Two DNA polymerases may be required for synthesis of the lagging DNA strand of simian virus 40 , 1990, Journal of virology.

[103]  L. Vassilev,et al.  Identification of an origin of bidirectional DNA replication in mammalian chromosomes , 1990, Cell.

[104]  P. Dijkwel,et al.  Replication initiates in a broad zone in the amplified CHO dihydrofolate reductase domain , 1990, Cell.

[105]  S. Francesconi,et al.  A DNA replication enhancer in Saccharomyces cerevisiae. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[106]  A. Spradling,et al.  Multiple replication origins are used during Drosophila chorion gene amplification , 1990, The Journal of cell biology.

[107]  L. Vassilev,et al.  Mapping initiation sites of DNA replication in vivo using polymerase chain reaction amplification of nascent strand segments. , 1989, Nucleic acids research.

[108]  H. Cedar,et al.  Mapping replication units in animal cells , 1989, Cell.

[109]  F. Kafatos,et al.  Amplification enhancers and replication origins in the autosomal chorion gene cluster of Drosophila. , 1989, EMBO Journal.

[110]  C. Newlon,et al.  A yeast replication origin consists of multiple copies of a small conserved sequence , 1988, Cell.

[111]  J. Huberman,et al.  The in vivo replication origin of the yeast 2μm plasmid , 1987, Cell.

[112]  M. DePamphilis,et al.  The origin of bidirectional DNA replication in polyoma virus. , 1987, The EMBO journal.

[113]  Y. Kohara,et al.  The distribution and properties of RNA primed initiation sites of DNA synthesis at the replication origin of Escherichia coli chromosome. , 1985, Nucleic acids research.

[114]  J. Bailey,et al.  Deletion mutations affecting autonomously replicating sequence ARS1 of Saccharomyces cerevisiae. , 1984, Molecular and cellular biology.

[115]  M. DePamphilis,et al.  Initiation of SV40 DNA replication in vivo: Location and structure of 5′ ends of DNA synthesized in the ori region , 1982, Cell.

[116]  R. W. Davis,et al.  Isolation and characterisation of a yeast chromosomal replicator , 1979, Nature.

[117]  T. Okazaki,et al.  Mechanism of DNA chain growth XVI. Analyses of RNA-linked DNA pieces in Escherichia coli with polynucleotide kinase. , 1975, Journal of molecular biology.

[118]  Y. Kurosawa,et al.  Assay of RNA-linked nascent DNA pieces with polynucleotide kinase. , 1975, Biochemical and biophysical research communications.

[119]  T. Okazaki,et al.  Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains. , 1968, Proceedings of the National Academy of Sciences of the United States of America.

[120]  J. W. Little.  [34a] An exonuclease induced by bacteriophage lambda , 1967 .

[121]  C. Radding.  Regulation of lambda exonuclease. I. Properties of lambda exonuclease purified from lysogens of lambda T11 and wild type. , 1966, Journal of molecular biology.

[122]  François Jacob,et al.  On the Regulation of DNA Replication in Bacteria , 1963 .