Three-dimensional structure of echistatin and dynamics of the active site

[1]  D. Veber,et al.  NMR and molecular modeling characterization of RGD containing peptides. , 2009, International journal of peptide and protein research.

[2]  D. Veber,et al.  The solution conformation Ac‐Pen‐Arg‐Gly‐Asp‐Cys‐OH, a potent fibrinogen receptor antagonist , 1993, Biopolymers.

[3]  H. Dyson,et al.  Comparison of backbone and tryptophan side-chain dynamics of reduced and oxidized Escherichia coli thioredoxin using 15N NMR relaxation measurements. , 1993, Biochemistry.

[4]  K. Dahlman-Wright,et al.  Backbone dynamics of the glucocorticoid receptor DNA-binding domain. , 1992, Biochemistry.

[5]  R A Smith,et al.  Loop mobility in a four-helix-bundle protein: 15N NMR relaxation measurements on human interleukin-4. , 1992, Biochemistry.

[6]  T. Gadek,et al.  Structural studies of potent constrained RGD peptides , 1992 .

[7]  C. E. Peishoff,et al.  Investigation of conformational specificity at GPIIb/IIIa: evaluation of conformationally constrained RGD peptides. , 1992, Journal of medicinal chemistry.

[8]  R. Powers,et al.  Analysis of the backbone dynamics of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase using 15N relaxation measurements. , 1992, Biochemistry.

[9]  T. Siahaan,et al.  Conformational study of cyclo(1,5)-Ac-Pen-Arg-Gly-Asp-Cys-NH2 in water by NMR and molecular dynamics. , 1992, Biochemical and biophysical research communications.

[10]  J. Calvete,et al.  The disulfide bridge pattern of snake venom disintegrins, flavoridin and echistatin , 1992, FEBS letters.

[11]  M Ikura,et al.  Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible. , 1992, Biochemistry.

[12]  A. Palmer,et al.  Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy. , 1992, Biochemistry.

[13]  M H Saier,et al.  Backbone dynamics of the Bacillus subtilis glucose permease IIA domain determined from 15N NMR relaxation measurements. , 1992, Biochemistry.

[14]  D. M. Schneider,et al.  Fast internal main-chain dynamics of human ubiquitin. , 1992, Biochemistry.

[15]  I. Shimada,et al.  A 1H-NMR study of the solution conformation of cyclo(GRGDSPA): conformational effects on the physiological activity. , 1992, Biochemical and biophysical research communications.

[16]  V. Garsky,et al.  Proton NMR assignments and secondary structure of the snake venom protein echistatin. , 1991, Biochemistry.

[17]  V. Saudek,et al.  The secondary structure of echistatin from 1H-NMR, circular-dichroism and Raman spectroscopy. , 1991, European journal of biochemistry.

[18]  C. Dalvit,et al.  1H NMR studies of echistatin in solution. Sequential resonance assignments and secondary structure. , 1991, European journal of biochemistry.

[19]  R. Cooke,et al.  Nuclear magnetic resonance studies of the snake toxin echistatin. 1H resonance assignments and secondary structure. , 1991, European journal of biochemistry.

[20]  R. Timpl,et al.  Arg‐Gly‐Asp constrained within cyclic pentapoptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1 , 1991, FEBS letters.

[21]  V. Saudek,et al.  Three-dimensional structure of echistatin, the smallest active RGD protein. , 1991, Biochemistry.

[22]  G. Wagner,et al.  Solution structure of kistrin, a potent platelet aggregation inhibitor and GP IIb-IIIa antagonist. , 1991, Science.

[23]  A M Gronenborn,et al.  Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy. , 1991, Science.

[24]  P. Wright,et al.  Intramolecular motions of a zinc finger DNA-binding domain from Xfin characterized by proton-detected natural abundance carbon-13 heteronuclear NMR spectroscopy , 1991 .

[25]  R. Levy,et al.  Analysis of side‐chain conformational distributions in neutrophil peptide‐5 nmr structures , 1990, Biopolymers.

[26]  V. Garsky,et al.  Echistatin is a potent inhibitor of bone resorption in culture , 1990, The Journal of cell biology.

[27]  Fumio Hirata,et al.  Conserving energy during molecular dynamics simulations of water, proteins, and proteins in water , 1990 .

[28]  A. Gronenborn,et al.  Analysis of the backbone dynamics of interleukin-1.beta. using two-dimensional inverse detected heteronuclear nitrogen-15-proton NMR spectroscopy , 1990 .

[29]  Paul C. Driscoll,et al.  Deviations from the simple two-parameter model-free approach to the interpretation of nitrogen-15 nuclear magnetic relaxation of proteins , 1990 .

[30]  M. Polokoff,et al.  Characterization and platelet inhibitory activity of bitistatin, a potent arginine-glycine-aspartic acid-containing peptide from the venom of the viper Bitis arietans. , 1989, The Journal of biological chemistry.

[31]  J Otlewski,et al.  Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing. , 1989, Journal of molecular biology.

[32]  R. Jordan,et al.  Abolition of in vivo platelet thrombus formation in primates with monoclonal antibodies to the platelet GPIIb/IIIa receptor. Correlation with bleeding time, platelet aggregation, and blockade of GPIIb/IIIa receptors. , 1989, Circulation.

[33]  R. Levy,et al.  Solution structures of proteins from NMR data and modeling: alternative folds for neutrophil peptide 5. , 1989, Biochemistry.

[34]  L. Kay,et al.  Backbone dynamics of proteins as studied by 15N inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease. , 1989, Biochemistry.

[35]  R. Shebuski,et al.  Demonstration of Ac-Arg-Gly-Asp-Ser-NH2 as an Antiaggregatory Agent in the Dog by Intracoronary Administration , 1989, Thrombosis and Haemostasis.

[36]  A. Bax,et al.  P.COSY, a sensitive alternative for double-quantum-filtered COSY , 1988 .

[37]  S. Suhai,et al.  Secondary structure of the Arg-Gly-Asp recognition site in proteins involved in cell-surface adhesion. Evidence for the occurrence of nested beta-bends in the model hexapeptide GRGDSP. , 1988, European journal of biochemistry.

[38]  G. Wagner,et al.  Measurement of 13C relaxation times in proteins by two-dimensional heteronuclear 1H-13C correlation spectroscopy , 1988 .

[39]  H. Gold,et al.  Monoclonal antibody against the platelet glycoprotein (GP) IIb/IIIa receptor prevents coronary artery reocclusion after reperfusion with recombinant tissue-type plasminogen activator in dogs. , 1988, The Journal of clinical investigation.

[40]  K. Wüthrich.  NMR of proteins and nucleic acids , 1988 .

[41]  H. Gold,et al.  Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GPIIb/IIIa antibody in a canine preparation. , 1988, Circulation.

[42]  K. Wüthrich,et al.  Pre-TOCSY, a new experiment for obtaining complete 2D 1H NMR spectra of proteins in H2O solution , 1987 .

[43]  S. Niewiarowski,et al.  Trigramin. A low molecular weight peptide inhibiting fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex. , 1987, The Journal of biological chemistry.

[44]  E Ruoslahti,et al.  New perspectives in cell adhesion: RGD and integrins. , 1987, Science.

[45]  Timothy F. Havel,et al.  Protein structures in solution by nuclear magnetic resonance and distance geometry. The polypeptide fold of the basic pancreatic trypsin inhibitor determined using two different algorithms, DISGEO and DISMAN. , 1987, Journal of molecular biology.

[46]  L. Mueller.  P.E.COSY, a simple alternative to E.COSY , 1987 .

[47]  Richard O. Hynes,et al.  Integrins: A family of cell surface receptors , 1987, Cell.

[48]  A. Capron,et al.  Trypanosoma cruzi infection inhibited by peptides modeled from a fibronectin cell attachment domain. , 1986, Science.

[49]  M. Humphries,et al.  A synthetic peptide from fibronectin inhibits experimental metastasis of murine melanoma cells. , 1986, Science.

[50]  E Ruoslahti,et al.  Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors. , 1986, Science.

[51]  E. Ruoslahti,et al.  Arg-Gly-Asp: A versatile cell recognition signal , 1986, Cell.

[52]  R. Hynes,et al.  Interaction of fibronectin with its receptor on platelets , 1985, Cell.

[53]  B. Coller.  A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex. , 1985, The Journal of clinical investigation.

[54]  J. Lakowicz,et al.  Analysis of fluorescence decay kinetics from variable-frequency phase shift and modulation data. , 1984, Biophysical journal.

[55]  K. Wüthrich,et al.  Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. , 1983, Biochemical and biophysical research communications.

[56]  A. Szabó,et al.  Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity , 1982 .

[57]  D. States,et al.  A two-dimensional nuclear overhauser experiment with pure absorption phase in four quadrants☆ , 1982 .

[58]  Ronald M. Levy,et al.  NMR relaxation parameters in molecules with internal motion: exact Langevin trajectory results compared with simplified relaxation models , 1981 .

[59]  K Wüthrich,et al.  A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules. , 1980, Biochemical and biophysical research communications.

[60]  Richard R. Ernst,et al.  Coherence transfer in the rotating frame , 1979 .

[61]  A. Redfield,et al.  Quadrature fourier NMR detection: Simple multiplex for dual detection and discussion , 1975 .

[62]  C. R. Middaugh,et al.  Statistical determination of the average values of the extinction coefficients of tryptophan and tyrosine in native proteins. , 1992, Analytical biochemistry.

[63]  Timothy F. Havel,et al.  NMR structure determination in solution: a critique and comparison with X-ray crystallography. , 1992, Annual review of biophysics and biomolecular structure.

[64]  D. Lide.  Handbook of Chemistry and Physics , 1992 .

[65]  G. Marius Clore,et al.  Applications of three- and four-dimensional heteronuclear NMR spectroscopy to protein structure determination , 1991 .

[66]  S. Wold,et al.  The Three-Dimensional Structure of the RGD (Arg-Gly-Asp) Adhesion Sequence of Fibronectin; NMR Studies of the Peptides RGDS and GRGDSP. , 1990 .

[67]  J. Lakowicz.  Principles of fluorescence spectroscopy , 1983 .

[68]  R. C. Weast.  CRC Handbook of Chemistry and Physics , 1973 .