Circulating Levels of the Shed Scavenger Receptor sCD163 and Association with Outcome of Critically Ill Patients

[1]  L. Su,et al.  Diagnostic value of urine sCD163 levels for sepsis and relevant acute kidney injury: a prospective study , 2012, BMC Nephrology.

[2]  H. Møller.  Soluble CD163 , 2012, Scandinavian journal of clinical and laboratory investigation.

[3]  G. Van den Berghe,et al.  Early versus Late Parenteral Nutrition in Critically Ill Adults , 2011, The New England journal of medicine.

[4]  S. Moestrup,et al.  Kupffer cells are activated in cirrhotic portal hypertension and not normalised by TIPS , 2011, Gut.

[5]  J. Ge,et al.  Usefulness of N-terminal pro-brain natriuretic peptide and C-reactive protein to predict ICU mortality in unselected medical ICU patients: a prospective, observational study , 2011, Critical care.

[6]  S. Moestrup,et al.  Tumor necrosis factor -converting enzyme (TACE/ADAM17) mediates ectodomain shedding of the scavenger receptor CD163 , 2010 .

[7]  D. Payen,et al.  Bench-to-bedside review: Glucose and stress conditions in the intensive care unit , 2010, Critical care.

[8]  H. Ashrafian,et al.  Anti-inflammatory haemoglobin scavenging monocytes are induced following coronary artery bypass surgery. , 2010, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[9]  S. Moestrup,et al.  Soluble macrophage-derived CD163: a homogenous ectodomain protein with a dissociable haptoglobin-hemoglobin binding. , 2010, Immunobiology.

[10]  D. Vergani,et al.  Role of monocytes and macrophages in experimental and human acute liver failure. , 2010, World journal of gastroenterology.

[11]  H. Nauwynck,et al.  Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy. , 2010, Molecular immunology.

[12]  R. Star,et al.  Animal models of sepsis and sepsis-induced kidney injury. , 2009, The Journal of clinical investigation.

[13]  S. Faubel.  Acute kidney injury and multiple organ dysfunction syndrome. , 2009, Minerva urologica e nefrologica = The Italian journal of urology and nephrology.

[14]  G. Van den Berghe,et al.  The effect of strict blood glucose control on biliary sludge and cholestasis in critically ill patients. , 2009, The Journal of clinical endocrinology and metabolism.

[15]  Greet Van den Berghe,et al.  Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study , 2009, The Lancet.

[16]  S. Moestrup,et al.  New immunological serum markers in bacteraemia: anti‐inflammatory soluble CD163, but not proinflammatory high mobility group‐box 1 protein, is related to prognosis , 2008, Clinical and experimental immunology.

[17]  B. Bloom.  Macrophage activation is a key component in the pathogenesis of systemic juvenile idiopathic arthritis: comment on the article by Blessing et al. , 2007, Arthritis and rheumatism.

[18]  William M. Lee,et al.  Soluble CD163 from activated macrophages predicts mortality in acute liver failure. , 2007, Journal of hepatology.

[19]  B. Uitdehaag,et al.  Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis , 2007, Journal of Neuroimmunology.

[20]  A. Ramanan,et al.  The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis. , 2007, Arthritis and rheumatism.

[21]  K. Larsen,et al.  Diagnostic value of soluble CD163 serum levels in patients suspected of meningitis: Comparison with CRP and procalcitonin , 2007, Scandinavian journal of infectious diseases.

[22]  J. Carrero,et al.  Changes in fat mass correlate with changes in soluble sCD163, a marker of mature macrophages, in patients with CKD. , 2006, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[23]  M. Kurrer,et al.  Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsis , 2006, European journal of haematology.

[24]  E. Schneider,et al.  Soluble CD163: An age-dependent, anti-inflammatory biomarker predicting outcome in sepsis. , 2006, Critical care medicine.

[25]  S. Moestrup,et al.  Macrophage serum markers in pneumococcal bacteremia: Prediction of survival by soluble CD163* , 2006, Critical care medicine.

[26]  S. Moestrup,et al.  CD163 positive subsets of blood dendritic cells: the scavenging macrophage receptors CD163 and CD91 are coexpressed on human dendritic cells and monocytes. , 2006, Immunobiology.

[27]  G. Van den Berghe,et al.  Intensive insulin therapy in the medical ICU. , 2006, The New England journal of medicine.

[28]  S. Moestrup,et al.  The monocytic lineage specific soluble CD163 is a plasma marker of coronary atherosclerosis. , 2006, Atherosclerosis.

[29]  S. Moestrup,et al.  Soluble haemoglobin scavenger receptor (sCD163) in patients with suspected community‐acquired infections , 2006, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[30]  T. K. van den Berg,et al.  The macrophage scavenger receptor CD163. , 2005, Immunobiology.

[31]  P. Högger,et al.  Oxidative stress and 8-iso-prostaglandin F2α induce ectodomain shedding of CD163 and release of tumor necrosis factor-α from human monocytes , 2005 .

[32]  N. Horiike,et al.  Expression of CD163 in the liver of patients with viral hepatitis. , 2005, Pathology, research and practice.

[33]  M. Gladwin,et al.  The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease. , 2005, JAMA.

[34]  M. Kurrer,et al.  Soluble hemoglobin–haptoglobin scavenger receptor CD163 as a lineage‐specific marker in the reactive hemophagocytic syndrome , 2005, European journal of haematology.

[35]  P. Högger,et al.  Oxidative stress and 8-iso-prostaglandin F(2alpha) induce ectodomain shedding of CD163 and release of tumor necrosis factor-alpha from human monocytes. , 2005, Free radical biology & medicine.

[36]  J. Himmelfarb.  POOR NUTRITIONAL STATUS AND INFLAMMATION: Linking Oxidative Stress and Inflammation in Kidney Disease: Which is the Chicken and Which is the Egg? , 2004 .

[37]  P. Guyre,et al.  Cross‐linking of FcγR triggers shedding of the hemoglobin‐haptoglobin scavenger receptor CD163 , 2004, Journal of leukocyte biology.

[38]  E. Hahn,et al.  Multifactorial risk analysis of bone marrow histiocytic hyperplasia with hemophagocytosis in critically ill medical patients—A postmortem clinicopathologic analysis , 2004, Critical care medicine.

[39]  N. Horiike,et al.  Soluble CD163 in patients with liver diseases: very high levels of soluble CD163 in patients with fulminant hepatic failure , 2004, Journal of Gastroenterology.

[40]  F. Bach,et al.  Heme oxygenase-1: unleashing the protective properties of heme. , 2003, Trends in immunology.

[41]  Mark B Pepys,et al.  C-reactive protein: a critical update. , 2003, The Journal of clinical investigation.

[42]  A. Levy,et al.  Genetically Determined Heterogeneity in Hemoglobin Scavenging and Susceptibility to Diabetic Cardiovascular Disease , 2003, Circulation research.

[43]  H. M. Soliman,et al.  C-reactive protein levels correlate with mortality and organ failure in critically ill patients. , 2003, Chest.

[44]  G. Van den Berghe,et al.  Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. , 2003, The Journal of clinical endocrinology and metabolism.

[45]  S. Moestrup,et al.  Biological variation of soluble CD163 , 2003, Scandinavian journal of clinical and laboratory investigation.

[46]  P. Wallace,et al.  Endotoxin induces rapid metalloproteinase‐mediated shedding followed by up‐regulation of the monocyte hemoglobin scavenger receptor CD163 , 2002, Journal of leukocyte biology.

[47]  S. Moestrup,et al.  Characterization of an enzyme-linked immunosorbent assay for soluble CD163 , 2002, Scandinavian journal of clinical and laboratory investigation.

[48]  P. H. Petersen,et al.  Soluble CD163: a marker molecule for monocyte/macrophage activity in disease , 2002, Scandinavian journal of clinical and laboratory investigation. Supplementum.

[49]  Martine De Vos,et al.  Cartilage-derived morphogenetic protein-1 and -2 are endogenously expressed and stimulate proteoglycan synthesis in healthy and osteoarthritic human articular chondrocytes , 2001, Arthritis Research.

[50]  B. Bistrian,et al.  Intensive insulin therapy in critically ill patients. , 2002, The New England journal of medicine.

[51]  S. Moestrup,et al.  Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma. , 2002, Blood.

[52]  M. Brownlee.  Biochemistry and molecular cell biology of diabetic complications , 2001, Nature.

[53]  Roger Williams,et al.  The systemic inflammatory response syndrome in acute liver failure , 2000, Hepatology.

[54]  T. Langmann,et al.  Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro‐ and antiinflammatory stimuli , 2000, Journal of leukocyte biology.

[55]  E. DeLong,et al.  Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. , 1988, Biometrics.