Community approaches to improve resuscitation after out-of-hospital sudden cardiac arrest.

Sudden cardiac arrest (SCA) is a major cause of mortality in North America and other westernized societies, accounting for ≈10% of all deaths and up to 50% of heart disease–related death.1,2 The condition is characterized by an unexpected cardiovascular collapse due to an underlying cardiac cause.3 This definition, although useful as an intellectual foundation, is challenged by operational translation. The challenge of deriving a working case definition for SCA is important because different approaches for ascertainment and classification can influence efforts aimed at estimating incidence, improving prevention strategies, or directing resuscitation care. For example, various strategies may be used to determine incidence. Death certificates, emergency medical services (EMS) records, witness interviews, medical records, and medical examiner reports can be used singly or in combination to ascertain and classify SCA. Each approach has strengths and limitations. Death certificate ascertainment and classification, for example, are efficient and can be defined by specific objective coding criteria but often overestimate incidence because the approach includes people who do not die suddenly or do not truly die from cardiac causes.4 Conversely, death certificates exclude people who were successfully resuscitated. Thus, the “best” strategy for SCA ascertainment and classification depends in large part on the intent of the effort and available resources. The present clinical summary discusses approaches to improve resuscitation of out-of-hospital SCA and therefore focuses on SCA treated by EMS. From an epidemiological perspective, EMS-treated, out-of-hospital SCA constitutes a subset of all heart disease death events. As such, it excludes in-hospital events and out-of-hospital events that either do not have an emergency response or receive a response but no EMS treatment. The latter circumstance arises typically when there are signs of prolonged, irreversible death or when there is a “do not resuscitate” request and documentation.5 Although community-specific heterogeneity exists with …

[1]  T. Rea,et al.  Incidence of out-of-hospital cardiac arrest. , 2004, The American journal of cardiology.

[2]  R. Newcombe,et al.  Basics in advanced life support: a role for download audit and metronomes. , 2008, Resuscitation.

[3]  T. Rea,et al.  Emergency medical services and mortality from heart disease: a community study. , 2003, Annals of emergency medicine.

[4]  Hendrika Meischke,et al.  A community intervention by firefighters to increase 911 calls and aspirin use for chest pain. , 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[5]  D J Roe,et al.  Estimating effectiveness of cardiac arrest interventions: a logistic regression survival model. , 1997, Circulation.

[6]  Vinay Nadkarni,et al.  Reducing Barriers for Implementation of Bystander–Initiated Cardiopulmonary Resuscitation: A Scientific Statement From the American Heart Association for Healthcare Providers, Policymakers, and Community Leaders Regarding the Effectiveness of Cardiopulmonary Resuscitation , 2008, Circulation.

[7]  M. Weisfeldt,et al.  Cost-effectiveness of lay responder defibrillation for out-of-hospital cardiac arrest. , 2009, Annals of emergency medicine.

[8]  T. Rea,et al.  Manual chest compression vs use of an automated chest compression device during resuscitation following out-of-hospital cardiac arrest: a randomized trial. , 2006, JAMA.

[9]  D. Chamberlain,et al.  Why do chest compressions aid delayed defibrillation? , 2008, Resuscitation.

[10]  I. Stiell,et al.  Evaluating the effectiveness of dispatch-assisted cardiopulmonary resuscitation instructions. , 2007, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[11]  T. Aufderheide,et al.  Clinical evaluation of an inspiratory impedance threshold device during standard cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest* , 2005, Critical care medicine.

[12]  Douglas L Packer,et al.  Long-term outcomes of out-of-hospital cardiac arrest after successful early defibrillation. , 2003, The New England journal of medicine.

[13]  P. Steen,et al.  Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest. , 2007, Resuscitation.

[14]  J. Ornato,et al.  Use of an automated, load-distributing band chest compression device for out-of-hospital cardiac arrest resuscitation. , 2006, JAMA.

[15]  T. Rea,et al.  CPR during ischemia and reperfusion: a model for survival benefits. , 2008, Resuscitation.

[16]  B. Abella,et al.  Therapeutic hypothermia after cardiac arrest in clinical practice: Review and compilation of recent experiences , 2009, Critical care medicine.

[17]  B. Schmand,et al.  Cognitive impairment in survivors of out-of-hospital cardiac arrest. , 2004, American heart journal.

[18]  T. Rea,et al.  Cardiac Arrest in Schools , 2007, Circulation.

[19]  S. Bass Quality in the real world , 2006 .

[20]  Roger D. White,et al.  Hands-only (compression-only) cardiopulmonary resuscitation: a call to action for bystander response to adults who experience out-of-hospital sudden cardiac arrest: a science advisory for the public from the American Heart Association Emergency Cardiovascular Care Committee. , 2008, Circulation.

[21]  M. Copass,et al.  Changing incidence of out-of-hospital ventricular fibrillation, 1980-2000. , 2002, JAMA.

[22]  D K McKenas,et al.  Use of automated external defibrillators by a U.S. airline. , 2000, The New England journal of medicine.

[23]  H. Arntz,et al.  How Sudden Is Sudden Cardiac Death? , 2006, Circulation.

[24]  C. Callaway,et al.  Predicting survival after out-of-hospital cardiac arrest: role of the Utstein data elements. , 2010, Annals of emergency medicine.

[25]  R. Neumar,et al.  Consensus Process , 2022 .

[26]  R. Neumar,et al.  Inter-hospital variability in post-cardiac arrest mortality. , 2009, Resuscitation.

[27]  J. Soar,et al.  The use of CPR feedback/prompt devices during training and CPR performance: A systematic review. , 2009, Resuscitation.

[28]  T. Rea,et al.  Withholding Resuscitation: A New Approach to Prehospital End-of-Life Decisions , 2006, Annals of Internal Medicine.

[29]  Stig Steen,et al.  Treatment of out-of-hospital cardiac arrest with LUCAS, a new device for automatic mechanical compression and active decompression resuscitation. , 2005, Resuscitation.

[30]  G. Ewy,et al.  Cardiocerebral resuscitation improves neurologically intact survival of patients with out-of-hospital cardiac arrest. , 2008, Annals of emergency medicine.

[31]  Michael Holzer,et al.  Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest , 2002 .

[32]  O. Gómez-Marín,et al.  Change in survival from out-of-hospital cardiac arrest and its effect on coronary heart disease mortality, Minneapolis-St. Paul. The Minnesota Heart Survey. , 1991, American journal of epidemiology.

[33]  Roger D. White,et al.  The unacceptable disparity in cardiac arrest survival among American communities. , 2009, Annals of emergency medicine.

[34]  R. Sinert,et al.  Update: Prevention of contrast-induced nephropathy in the emergency department. , 2007, Annals of emergency medicine.

[35]  D J Roe,et al.  Outcomes of rapid defibrillation by security officers after cardiac arrest in casinos. , 2000, The New England journal of medicine.

[36]  J. Ornato,et al.  Improving survival from sudden cardiac arrest , 1991 .

[37]  T. Rea,et al.  Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. , 2005, Resuscitation.

[38]  R. Berg,et al.  Minimally interrupted cardiac resuscitation by emergency medical services for out-of-hospital cardiac arrest. , 2008, JAMA.

[39]  Dispatcher-assisted cardiopulmonary resuscitation and survival in cardiac arrest. , 2002 .

[40]  R. Koster,et al.  Interruption of cardiopulmonary resuscitation with the use of the automated external defibrillator in out-of-hospital cardiac arrest. , 2003, Annals of emergency medicine.

[41]  B. King Chain of Survival , 2009 .

[42]  W. B. Kouwenhoven,et al.  Closed-chest cardiac massage. , 1960, JAMA.

[43]  T. Rea,et al.  Increasing Use of Cardiopulmonary Resuscitation During Out-of-Hospital Ventricular Fibrillation Arrest: Survival Implications of Guideline Changes , 2006, Circulation.

[44]  R. L. Page,et al.  The Automated External Defibrillator , 2007, Journal of cardiovascular electrophysiology.

[45]  S. Bernard,et al.  Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. , 2002, The New England journal of medicine.

[46]  J P Ornato,et al.  Public-access Defibrillation and Survival after Out-of-hospital Cardiac Arrest Recommended Citation Public-access Defibrillation and Survival after Out-of-hospital Cardiac Arrest , 2022 .

[47]  D. Siscovick Challenges in cardiac arrest research: data collection to assess outcomes. , 1993, Annals of emergency medicine.

[48]  Bonnie Lynch,et al.  The American Heart Association CPR Anytime Program: the potential impact of highly accessible training in cardiopulmonary resuscitation. , 2006, Journal of cardiopulmonary rehabilitation.

[49]  Arthur L Kellermann,et al.  CARES: Cardiac Arrest Registry to Enhance Survival. , 2009, Annals of emergency medicine.

[50]  K. Furie,et al.  Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. , 2008, Circulation.

[51]  T. Rea,et al.  Dispatcher-Assisted Cardiopulmonary Resuscitation: Risks for Patients Not in Cardiac Arrest , 2010, Circulation.

[52]  N. Fineberg,et al.  Limited response to cardiac arrest by police equipped with automated external defibrillators: lack of survival benefit in suburban and rural Indiana--the police as responder automated defibrillation evaluation (PARADE). , 2001, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[53]  Mohamud Daya,et al.  Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large U.S. community. , 2004, Journal of the American College of Cardiology.

[54]  Greg Sinibaldi,et al.  Incidence of EMS-treated out-of-hospital cardiac arrest in the United States. , 2004, Resuscitation.

[55]  Roger D. White,et al.  Evolution of a community-wide early defibrillation programme experience over 13 years using police/fire personnel and paramedics as responders. , 2005, Resuscitation.

[56]  T. Rea,et al.  Temporal Patterns in Long-Term Survival After Resuscitation From Out-of-Hospital Cardiac Arrest , 2003, Circulation.

[57]  C. Callaway,et al.  Regional variation in out-of-hospital cardiac arrest incidence and outcome. , 2008, JAMA.

[58]  George A. Wells,et al.  Advanced Cardiac Life Support in Out-of-Hospital Cardiac Arrest , 2004 .

[59]  Thomas D Rea,et al.  Public Access Defibrillation in Out-of-Hospital Cardiac Arrest: A Community-Based Study , 2004, Circulation.

[60]  H. Morita,et al.  Continuous Improvements in “Chain of Survival” Increased Survival After Out-of-Hospital Cardiac Arrests: A Large-Scale Population-Based Study , 2009, Circulation.

[61]  Benjamin S Abella,et al.  The challenge of CPR quality: improvement in the real world. , 2008, Resuscitation.

[62]  Benjamin S Abella,et al.  Induced hypothermia is underused after resuscitation from cardiac arrest: a current practice survey. , 2005, Resuscitation.

[63]  Jonathan A Drezner,et al.  Effectiveness of Emergency Response Planning for Sudden Cardiac Arrest in United States High Schools With Automated External Defibrillators , 2009, Circulation.

[64]  Lance B Becker,et al.  Resuscitation after cardiac arrest: a 3-phase time-sensitive model. , 2002, JAMA.

[65]  Jo Kramer-Johansen,et al.  Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest , 2005 .

[66]  D. Beiser,et al.  Cardiac catheterization is underutilized after in-hospital cardiac arrest. , 2008, Resuscitation.

[67]  D. Levy,et al.  Temporal Trends in Coronary Heart Disease Mortality and Sudden Cardiac Death From 1950 to 1999: The Framingham Heart Study , 2004, Circulation.