Total fluorine, extractable organic fluorine, perfluorooctane sulfonate and other related fluorochemicals in liver of Indo-Pacific humpback dolphins (Sousa chinensis) and finless porpoises (Neophocaena phocaenoides) from South China.

The concentrations of 10 PFCs (perfluorinated compounds: PFOS, PFHxS, PFOSA, N-EtFOSA, PFDoDA, PFUnDA, PFDA, PFNA, PFOA, and PFHpA) were measured in liver samples of Indo-Pacific humpback dolphins (Sousa chinensis) (n=10) and finless porpoises (Neophocaena phocaenoides) (n=10) stranded in Hong Kong between 2003 and 2007. PFOS was the dominant PFC in the tissues at concentrations ranging at 26-693 ng/g ww in dolphins and 51.3-262 ng/g ww in porpoises. A newly developed combustion ion chromatography for fluorine was applied to measure total fluorine (TF) and extractable organic fluorine (EOF) in these liver samples to understand PFC contamination using the concept of mass balance analysis. Comparisons between the amounts of known PFCs and EOF in the livers showed that a large proportion (approximately 70%) of the organic fluorine in both species is of unknown origin. These investigations are critical for a comprehensive assessment of the risks of these compounds to humans and other receptors.

[1]  Paul D. Jones,et al.  Accumulation of perfluorooctane sulfonate in marine mammals. , 2001, Environmental science & technology.

[2]  Nobuyoshi Yamashita,et al.  Analysis of trifluoroacetic acid and other short-chain perfluorinated acids (C2-C4) in precipitation by liquid chromatography-tandem mass spectrometry: comparison to patterns of long-chain perfluorinated acids (C5-C18). , 2008, Analytica chimica acta.

[3]  E. Parsons.  Trace element concentrations in the tissues of cetaceans from Hong Kong's territorial waters , 1999, Environmental Conservation.

[4]  N. Kajiwara,et al.  Geographical distribution of polybrominated diphenyl ethers (PBDEs) and organochlorines in small cetaceans from Asian waters. , 2006, Chemosphere.

[5]  Kurunthachalam Kannan,et al.  Perfluoroalkyl sulfonates and perfluorocarboxylates in two wastewater treatment facilities in Kentucky and Georgia. , 2007, Water research.

[6]  K. Hansen,et al.  Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices. , 2001, Environmental science & technology.

[7]  Kurunthachalam Kannan,et al.  Perfluorinated contaminants in sediments and aquatic organisms collected from shallow water and tidal flat areas of the Ariake Sea, Japan: environmental fate of perfluorooctane sulfonate in aquatic ecosystems. , 2006, Environmental science & technology.

[8]  T. Jefferson,et al.  Petroleum hydrocarbons, polycyclic aromatic hydrocarbons, organochlorine pesticides and polychlorinated biphenyls in tissues of Indo-Pacific humpback dolphins from south China waters. , 2005, Marine pollution bulletin.

[9]  Derek C G Muir,et al.  Circumpolar study of perfluoroalkyl contaminants in polar bears (Ursus maritimus). , 2005, Environmental science & technology.

[10]  J. Giesy,et al.  Peer Reviewed: Perfluorochemical Surfactants in the Environment , 2002 .

[11]  R. Dietz,et al.  Preliminary screening of perfluorooctane sulfonate (PFOS) and other fluorochemicals in fish, birds and marine mammals from Greenland and the Faroe Islands. , 2005, Environmental pollution.

[12]  Robert C Buck,et al.  Absorption, distribution, metabolism, and elimination of 8-2 fluorotelomer alcohol in the rat. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.

[13]  Paul D. Jones,et al.  Comparison of gene expression methods to identify genes responsive to perfluorooctane sulfonic acid. , 2005, Environmental toxicology and pharmacology.

[14]  N. Kajiwara,et al.  Polybrominated diphenyl ethers (PBDEs) and organochlorines in small cetaceans from Hong Kong waters: levels, profiles and distribution. , 2005, Marine pollution bulletin.

[15]  Robert A Hoke,et al.  Polyfluorinated chemicals in a spatially and temporally integrated food web in the Western Arctic. , 2008, Chemosphere.

[16]  T. Jefferson,et al.  Population biology of the indo-pacific hump-backed dolphin in Hong Kong waters , 2000 .

[17]  N Yamashita,et al.  Perfluorinated compounds in coastal waters of Hong Kong, South China, and Korea. , 2004, Environmental science & technology.

[18]  John P Giesy,et al.  Perfluorooctanesulfonate and related fluorinated hydrocarbons in marine mammals, fishes, and birds from coasts of the Baltic and the Mediterranean Seas. , 2002, Environmental science & technology.

[19]  Pawel Rostkowski,et al.  Determination of trace levels of total fluorine in water using combustion ion chromatography for fluorine: a mass balance approach to determine individual perfluorinated chemicals in water. , 2007, Journal of chromatography. A.

[20]  Yuan Wang,et al.  Perfluorooctane sulfonate and other fluorochemicals in waterbird eggs from south China. , 2008, Environmental science & technology.

[21]  Nobuyoshi Yamashita,et al.  Is fish a major source of fluorinated surfactants and repellents in humans living on the Baltic Coast? , 2006, Environmental science & technology.

[22]  Tsuyoshi Okazawa,et al.  Analysis of perfluorinated acids at parts-per-quadrillion levels in seawater using liquid chromatography-tandem mass spectrometry. , 2004, Environmental science & technology.

[23]  Timothy J Wallington,et al.  Degradation of fluorotelomer alcohols: a likely atmospheric source of perfluorinated carboxylic acids. , 2004, Environmental science & technology.

[24]  S. Tanabe,et al.  Isomer-Specific Accumulation and Toxic Assessment of Polychlorinated Biphenyls, Including Coplanar Congeners, in Cetaceans from the North Pacific and Asian Coastal Waters , 2000, Archives of environmental contamination and toxicology.

[25]  Ning Wang,et al.  Aerobic biotransformation of 14C-labeled 8-2 telomer B alcohol by activated sludge from a domestic sewage treatment plant. , 2005, Environmental science & technology.

[26]  S. Tanabe,et al.  Contamination by persistent organochlorines in small cetaceans from Hong Kong coastal waters , 1999 .

[27]  N. Kajiwara,et al.  Isomer specific determination of hexabromocyclododecanes (HBCDs) in small cetaceans from the South China Sea--Levels and temporal variation. , 2007, Marine pollution bulletin.

[28]  An assessment of the risks associated with polychlorinated biphenyls found in the stomach contents of stranded Indo-Pacific Humpback Dolphins (Sousa chinensis) and Finless Porpoises (Neophocaena phocaenoides) from Hong Kong waters. , 2006, Chemosphere.

[29]  U. Siebert,et al.  Baseline study of perfluorochemicals in harbour porpoises (Phocoena phocoena) from Northern Europe. , 2004, Marine pollution bulletin.

[30]  Guibin Jiang,et al.  Perfluorooctanesulfonate and related fluorochemicals in human blood samples from China. , 2006, Environmental science & technology.

[31]  G. Jiang,et al.  Perfluorinated compounds and total and extractable organic fluorine in human blood samples from China. , 2008, Environmental science & technology.

[32]  K. Kannan,et al.  A baseline study of perfluorochemicals in Franciscana dolphin and Subantarctic fur seal from coastal waters of Southern Brazil. , 2008, Marine pollution bulletin.

[33]  N Yamashita,et al.  Perfluorinated compounds in the Pearl River and Yangtze River of China. , 2007, Chemosphere.

[34]  P. Jepson,et al.  PFOS and PFOA in the livers of harbour porpoises (Phocoena phocoena) stranded or bycaught around the UK. , 2008, Marine pollution bulletin.

[35]  Ning Wang,et al.  Fluorotelomer alcohol biodegradation-direct evidence that perfluorinated carbon chains breakdown. , 2005, Environmental science & technology.

[36]  K. Kannan,et al.  Chlorinated, brominated, and perfluorinated contaminants in livers of polar bears from Alaska. , 2005, Environmental science & technology.

[37]  Tsuyoshi Okazawa,et al.  Analysis of fluorotelomer alcohols, fluorotelomer acids, and short- and long-chain perfluorinated acids in water and biota. , 2005, Journal of chromatography. A.

[38]  Ronny Blust,et al.  Occurrence of perfluorooctane sulfonate and other perfluorinated alkylated substances in harbor porpoises from the Black Sea. , 2007, Environmental science & technology.

[39]  Pawel Rostkowski,et al.  Trace analysis of total fluorine in human blood using combustion ion chromatography for fluorine: a mass balance approach for the determination of known and unknown organofluorine compounds. , 2007, Journal of chromatography. A.

[40]  Nobuyoshi Yamashita,et al.  Occurrence of Perfluoroalkyl Surfactants in Water, Fish, and Birds from New York State , 2006, Archives of environmental contamination and toxicology.