Development of a novel computerised version of the Month Backwards Test: A comparison of performance in hospitalised elderly patients and final year medical students

BACKGROUND AND AIMS The Months Backwards Test (MBT) is a commonly used bedside test of cognitive function, but there is uncertainty as to optimal testing procedures. We examined performance among hospitalised elderly patients and cognitively intact young persons with verbal and computerised versions of the test. PARTICIPANTS AND METHODS Fifty acute elderly medical inpatients and fifty final year medical students completed verbal (MBTv) and computerised (MBTc) versions of the MBT and the Montreal Cognitive Assessment (MoCA). Completion time and errors were compared. RESULTS Thirty four participants scored <26 on the MoCA indicating significant cognitive impairment. The mean MoCA scores in the elderly medical group (23.6±3.4; range 13-28) were significantly lower than for the medical students (29.2±0.6; range 28-30: p<0.01). For the verbal months backwards test (MBTv), there were significantly more errors and longer completion times in the elderly medical patients (25.1±20.9 vs. 10.5±4.5; p<0.05). Completion times were 2-3 times longer for the MBTc compared to the MBTv (patients: 63.5±43.9 vs. students 20.3±4.4; p<0.05). There was high correlation between the two versions of the MBT (r=0.84) and also between the MBTc and the MoCA (r=0.85). The MBTc had higher correlation with visuospatial function (MBTc r=0.70, MBTv r=0.57). An MBTc cut-off time of 30s for distinguishing performance (pass/fail) had excellent sensitivity (100%) with modest specificity (44%) for cognitive impairment in elderly medical patients. CONCLUSION The computerised MBT allows accurate and efficient testing of attention and general cognition in clinical populations.

[1]  L. Lipsitz,et al.  Impaired Executive Function Is Associated with Delirium After Coronary Artery Bypass Graft Surgery , 2006, Journal of the American Geriatrics Society.

[2]  H. Halstead Mental Tests in Senile Dementia , 1944 .

[3]  John Duncan,et al.  Executive function and fluid intelligence after frontal lobe lesions , 2009, Brain : a journal of neurology.

[4]  A M Stiggelbout,et al.  Assessment of cognition in Parkinson’s disease , 2003, Neurology.

[5]  D. Mark,et al.  Serial Sevens: Not the Most Effective Test of Mental Status in High School Athletes , 1997, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[6]  D. Meagher,et al.  The active management of delirium: improving detection and treatment , 2008 .

[7]  R. Petersen,et al.  Mild cognitive impairment , 2006, The Lancet.

[8]  M. Lezak,et al.  Neuropsychological assessment, 4th ed. , 2004 .

[9]  N. Venketasubramanian,et al.  The Montreal Cognitive Assessment is superior to the Mini-Mental State Examination in detecting patients at higher risk of dementia , 2012, Alzheimer's & Dementia.

[10]  L. Wahlund,et al.  Word sequence production in cognitive decline: Forward ever, backward never , 2008, Logopedics, phoniatrics, vocology.

[11]  D. Meagher,et al.  Attention! A good bedside test for delirium? , 2014, Journal of Neurology, Neurosurgery & Psychiatry.

[12]  D. Meagher,et al.  Improving delirium care through early intervention: from bench to bedside to boardroom , 2013, Journal of Neurology, Neurosurgery & Psychiatry.

[13]  Domján Andrea,et al.  World Medical Association Declaration of Helsinki (WMA) - Ethical principles for medical research involving human subjects , 2014 .

[14]  M. Roth,et al.  The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects , 1968, British Journal of Psychiatry.

[15]  W. Friedman Image and verbal processes in reasoning about the months of the year. , 1983 .

[16]  U Klose,et al.  Dynamic pattern of brain activation during sequencing of word strings evaluated by fMRI. , 1999, Brain research. Cognitive brain research.

[17]  R. Laforce,et al.  Months backward test as a reliable predictor of cognitive decline in mild Alzheimer's disease , 2013, Alzheimer's & Dementia.

[18]  J. Shuster,et al.  Diagnosing delirium in older emergency department patients: validity and reliability of the delirium triage screen and the brief confusion assessment method. , 2013, Annals of emergency medicine.

[19]  S K Inouye,et al.  Clarifying confusion: the confusion assessment method. A new method for detection of delirium. , 1990, Annals of internal medicine.

[20]  E. Kaplan,et al.  The assessment of aphasia and related disorders , 1972 .

[21]  E. Tolosa,et al.  Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force , 2007, Movement disorders : official journal of the Movement Disorder Society.

[22]  J P Wiley,et al.  Sport concussion assessment tool: baseline values for varsity collision sport athletes , 2009, British Journal of Sports Medicine.

[23]  D. Meagher,et al.  Evaluating attention in delirium: A comparison of bedside tests of attention , 2016, Geriatrics & gerontology international.

[24]  D. Meagher,et al.  Months backward test: A review of its use in clinical studies. , 2015, World journal of psychiatry.

[25]  R. Allen,et al.  Are forward and backward recall the same? A dual-task study of digit recall , 2012, Memory & Cognition.

[26]  Janet F Eary,et al.  Sport Concussion Assessment Tool – 2: Baseline Values for High School Athletes , 2012, British Journal of Sports Medicine.

[27]  S. Birge,et al.  A Simple Test of Central Processing Speed: An Extension of the Short Blessed Test , 1999, Journal of the American Geriatrics Society.

[28]  D. Benson,et al.  The Frontal Lobe Score: part I: construction of a mental status of frontal systems , 2000, Clinical rehabilitation.

[29]  S. Inouye,et al.  The Confusion Assessment Method: A Systematic Review of Current Usage , 2008, Journal of the American Geriatrics Society.

[30]  J. Cummings,et al.  The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment , 2005, Journal of the American Geriatrics Society.

[31]  J R Hodges,et al.  Cognitive assessment for clinicians , 1994, Journal of Neurology, Neurosurgery & Psychiatry.

[32]  Kathleen O'Sullivan,et al.  Delirium in an adult acute hospital population: predictors, prevalence and detection , 2013, BMJ Open.

[33]  R. Petersen,et al.  Mild cognitive impairment , 2006, The Lancet.

[34]  Adrian Tookman,et al.  Detection of delirium in the acute hospital. , 2010, Age and ageing.

[35]  P. Östberg,et al.  Adult norms and test-retest reliability for the Months Backward test: Durational and response accuracy measures , 2012, Logopedics, phoniatrics, vocology.

[36]  Susan M Resnick,et al.  Aging and prefrontal functions: dissociating orbitofrontal and dorsolateral abilities , 2004, Neurobiology of Aging.

[37]  Andreas Meyer-Lindenberg,et al.  Shared and distinct neurophysiological components of the digits forward and backward tasks as revealed by functional neuroimaging , 2004, Neuropsychologia.

[38]  G. Libben,et al.  The Assessment of Bilingual Aphasia , 1987 .

[39]  S. Hahn,et al.  Memory Impairment and Executive Dysfunction are Associated with Inadequately Controlled Diabetes in Older Adults , 2011, Journal of primary care & community health.