Suppression of reflexive saccades in younger and older adults: Age comparisons on an antisaccade task

Inhibitory control of prepotent responses has been examined by using the antisaccade task, during which a reflexive saccade toward a peripheral onset must be suppressed before an eye movement in the opposite direction from the onset can be executed. In the present experiments, we sought to determine whether older and younger adults would perform similarly on this task. Older adults had a harder time suppressing their reflexive responses, as measured by an increase in the proportion of saccade direction errors. Despite an age-related decline in saccade direction accuracy, the increase in saccade latency associated with the antisaccade condition was the same for both younger and older adults. These results support the view that the effectiveness of inhibitory control declines with age (Hasher & Zacks, 1988; Hasher, Zacks, & May, 1999).

[1]  K. Fukushima,et al.  Further analysis of the control of voluntary saccadic eye movements in schizophrenic patients , 1990, Biological Psychiatry.

[2]  P. E. Hallett,et al.  Primary and secondary saccades to goals defined by instructions , 1978, Vision Research.

[3]  Raymond M. Klein,et al.  The Magnitude of the Fixation Offset Effect with Endogenously and Exogenously Controlled Saccades , 1996, Journal of Cognitive Neuroscience.

[4]  D. Balota,et al.  Inhibition of return and visuospatial attention in healthy older adults and individuals with dementia of the Alzheimer type. , 1997, Neuropsychology.

[5]  R W Baloh,et al.  Age-related changes in visual tracking. , 1994, Journal of gerontology.

[6]  T. Salthouse.  The processing-speed theory of adult age differences in cognition. , 1996, Psychological review.

[7]  北川 まゆみ.  Relationship between antisaccades and the clinical symptoms in Parkinson's disease , 1995 .

[8]  G. Pearlson,et al.  Oculomotor performance in obsessive-compulsive disorder. , 1992, The American journal of psychiatry.

[9]  Cynthia P. May,et al.  Inhibitory control, circadian arousal, and age. , 1999 .

[10]  K. Fukushima,et al.  Voluntary control of saccadic eye movement in patients with frontal cortical lesions and Parkinsonian patients in comparison with that in Schizophrenics , 1994, Biological Psychiatry.

[11]  J. Pratt,et al.  Initiation and inhibition of saccadic eye movements in younger and older adults: an analysis of the gap effect. , 1997, The journals of gerontology. Series B, Psychological sciences and social sciences.

[12]  C Pierrot-Deseilligny,et al.  Cortical control of saccades in man. , 1991, Acta neurologica Belgica.

[13]  R. Roberts,et al.  Prefrontal cognitive processes: Working memory and inhibition in the antisaccade task. , 1994 .

[14]  John M. Findlay,et al.  Spatial and temporal factors in the predictive generation of saccadic eye movements , 1981, Vision Research.

[15]  René Müri,et al.  Cortical control of saccades , 1995, Annals of neurology.

[16]  P. E. Hallett,et al.  The predictability of saccadic latency in a novel voluntary oculomotor task , 1980, Vision Research.

[17]  R Freedman,et al.  Age Diminishes Performance on an Antisaccade Eye Movement Task , 1997, Neurobiology of Aging.

[18]  K. Rayner.  Eye Movements and Visual Cognition , 1992 .

[19]  M. Albert,et al.  The effect of increasing age on the latency for saccadic eye movements. , 1983, Journal of gerontology.

[20]  J. Henderson,et al.  High-level scene perception. , 1999, Annual review of psychology.

[21]  T. Carr,et al.  Inhibitory Processes in Attention, Memory and Language , 1994 .

[22]  W. C. Shipley.  A Self-Administering Scale for Measuring Intellectual Impairment and Deterioration , 1940 .

[23]  J Jonides,et al.  Programming saccadic eye movements. , 1988, Journal of experimental psychology. Human perception and performance.

[24]  Lynn Hasher,et al.  Working Memory, Comprehension, and Aging: A Review and a New View , 1988 .

[25]  Keith Rayner,et al.  Eye movement latencies for parafoveally presented words , 1978 .

[26]  K. Rayner.  Eye movements and visual cognition : scene perception and reading , 1992 .

[27]  J. Mcdowd.  Inhibition in attention and aging. , 1997, The journals of gerontology. Series B, Psychological sciences and social sciences.

[28]  L Hasher,et al.  Synchrony effects in inhibitory control over thought and action. , 1998, Journal of experimental psychology. Human perception and performance.

[29]  L. Hasher,et al.  Cognitive gerontology and attentional inhibition: a reply to Burke and McDowd. , 1997, The journals of gerontology. Series B, Psychological sciences and social sciences.

[30]  R. Wurtz,et al.  Fixation cells in monkey superior colliculus. II. Reversible activation and deactivation. , 1993, Journal of neurophysiology.

[31]  Lynn Hasher,et al.  Working Memory and Aging: Current Status of the Inhibitory View , 1996 .

[32]  S. Folstein,et al.  Saccades in Huntington's disease , 1987, Neurology.

[33]  Patricia A. Reuter-Lorenz,et al.  Oculomotor readiness and covert orienting: Differences between central and peripheral precues , 1992, Perception & psychophysics.

[34]  D. Burke.  Language, aging, and inhibitory deficits: evaluation of a theory. , 1997, The journals of gerontology. Series B, Psychological sciences and social sciences.

[35]  David A. Balota,et al.  Inhibition of Return and Visuospatial Attention in Healthy Older Adults and Individuals With Dementia of the Alzheimer Type , 1997 .

[36]  D. Munoz,et al.  Age-related performance of human subjects on saccadic eye movement tasks , 1998, Experimental Brain Research.

[37]  R. Wurtz,et al.  Role of the rostral superior colliculus in active visual fixation and execution of express saccades. , 1992, Journal of neurophysiology.