Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase.
暂无分享,去创建一个
J. Boehm | S. Kassis | John C. Lee | J. Adams | G. Seibel | P. Young | J. Adams | T. Gallagher | J. Laydon | M. J. Blumenthal | J. Lee | D. Lee | S. M. Fier-Thompson | J. Abt | M. E. Soreson | J. Smietana | R. Hall | R. Garigipati | P. Bender | K. Erhard | A. Krog | G. Hofmann | P. Sheldrake | P. Mcdonnell | S. Kumar | S. Kumar | Dennis Lee | P. Sheldrake | Susan M. Fier-Thompson | T. Gallagher | Mary Jane Blumenthal | Margaret E. Soreson
[1] J. Boehm,et al. 1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency. , 1996, Journal of medicinal chemistry.
[2] John C. Lee,et al. Identification of Mitogen-activated Protein (MAP) Kinase-activated Protein Kinase-3, a Novel Substrate of CSBP p38 MAP Kinase (*) , 1996, The Journal of Biological Chemistry.
[3] R. Davis,et al. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway , 1996, Molecular and cellular biology.
[4] Jiahuai Han,et al. Characterization of the Structure and Function of a Novel MAP Kinase Kinase (MKK6) (*) , 1996, The Journal of Biological Chemistry.
[5] M. Sticherling,et al. Role of eosinophil‐chemotactic C‐C chemokines in cutaneous inflammation , 1996, Journal of leukocyte biology.
[6] John C. Lee,et al. Human Mitogen-activated Protein Kinase CSBP1, but Not CSBP2, Complements a hog1 Deletion in Yeast (*) , 1995, The Journal of Biological Chemistry.
[7] Jerry L. Adams,et al. 2,4,5- triarylimidazole inhibitors of IL-1 biosynthesis , 1995 .
[8] Philip R. Cohen,et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1 , 1995, FEBS letters.
[9] M. Karin,et al. Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. , 1995, Science.
[10] Jiahuai Han,et al. Molecular cloning of human p38 MAP kinase. , 1995, Biochimica et biophysica acta.
[11] Jiahuai Han,et al. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms , 1995, Science.
[12] T. Hunter,et al. Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling , 1995, Cell.
[13] C. Marshall,et al. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation , 1995, Cell.
[14] I. Herskowitz. MAP kinase pathways in yeast: For mating and more , 1995, Cell.
[15] Jerry L. Adams,et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis , 1994, Nature.
[16] L Bibbs,et al. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. , 1994, Science.
[17] L. Gehrke,et al. Peripheral blood mononuclear cells stimulated with C5a or lipopolysaccharide to synthesize equivalent levels of IL-1 beta mRNA show unequal IL-1 beta protein accumulation but similar polyribosome profiles. , 1994, Journal of immunology.
[18] Elizabeth J. Goldsmith,et al. Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution , 1994, Nature.
[19] P. Bender,et al. Bicyclic Imidazoles as a Novel Class of Cytokine Biosynthesis Inhibitors , 1993, Annals of the New York Academy of Sciences.
[20] C. June,et al. Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14. , 1993, Journal of immunology.
[21] Susan S. Taylor,et al. Crystal structures of the myristylated catalytic subunit of cAMP‐dependent protein kinase reveal open and closed conformations , 1993, Protein science : a publication of the Protein Society.
[22] E. Winter,et al. An osmosensing signal transduction pathway in yeast. , 1993, Science.
[23] C. Schmitz‐Peiffer,et al. Use of a synthetic dodecapeptide (malantide) to measure the cyclic AMP-dependent protein kinase activity ratio in a variety of tissues. , 1990, The Biochemical journal.
[24] M. McGuire,et al. Synthetic and mechanistic studies on the preparation of pyridyl-substituted imidazothiazoles , 1988 .
[25] E. Moriconi,et al. Synthesis and reactions of cyclic amidines , 1968 .
[26] A. Hand,et al. Mechanism of action of bicyclic imidazoles defines a translational regulatory pathway for tumor necrosis factor alpha. , 1995, Journal of inflammation.
[27] B. Beutler,et al. Tumor Necrosis Factor: The molecules and Their Emerging Role in Medicine , 1992 .
[28] B. Beutler,et al. Translational control mediated by UA-rich sequences. , 1990, Enzyme.
[29] J. Lee,et al. Inhibition of monocyte IL-1 production by the anti-inflammatory compound, SK&F 86002. , 1988, International journal of immunopharmacology.
[30] P. Bender,et al. Antiinflammatory activity of 5,6-diaryl-2,3-dihydroimidazo[2,1-b]thiazoles. Isomeric 4-pyridyl and 4-substituted phenyl derivatives. , 1984, Journal of medicinal chemistry.