Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
暂无分享,去创建一个
Raymond T Chung | Yin Xia | N. Andrews | R. Chung | C. Woolf | F. Huang | Herbert Y. Lin | Jodie L Babitt | J. Campagna | Clifford J Woolf | Herbert Y Lin | A. Schneyer | Y. Sidis | Yin Xia | Nancy C Andrews | Jason A Campagna | Franklin W Huang | Diedra M Wrighting | Yisrael Sidis | Tarek A Samad | Alan L Schneyer | T. Samad | Diedra M. Wrighting
[1] Xiaoling Xu,et al. A Role of Smad4 in Iron Metabolism through the Positive Regulation of Hepcidin Expression , 2022 .
[2] A. West,et al. Interaction of Hemojuvelin with Neogenin Results in Iron Accumulation in Human Embryonic Kidney 293 Cells* , 2005, Journal of Biological Chemistry.
[3] C. Woolf,et al. Repulsive Guidance Molecule (RGMa), a DRAGON Homologue, Is a Bone Morphogenetic Protein Co-receptor* , 2005, Journal of Biological Chemistry.
[4] S. Arber,et al. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. , 2005, The Journal of clinical investigation.
[5] G. Pinkus,et al. A mouse model of juvenile hemochromatosis. , 2005, The Journal of clinical investigation.
[6] A. Brivanlou,et al. DRAGON, a Bone Morphogenetic Protein Co-receptor* , 2005, Journal of Biological Chemistry.
[7] E. Beutler,et al. Regulation of hepcidin transcription by interleukin-1 and interleukin-6. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[8] Jerry Kaplan,et al. Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization , 2004, Science.
[9] E. Nečas,et al. Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin. , 2004, Blood.
[10] Jiandie D. Lin,et al. Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice , 2004, Cell.
[11] N. Andrews,et al. Identification of a novel mutation (C321X) in HJV. , 2004, Blood.
[12] S. Strittmatter,et al. RGM and its receptor neogenin regulate neuronal survival , 2004, Nature Cell Biology.
[13] Srikanth Rajagopalan,et al. Neogenin mediates the action of repulsive guidance molecule , 2004, Nature Cell Biology.
[14] J. Barton,et al. Genetic abnormalities and juvenile hemochromatosis: mutations of the HJV gene encoding hemojuvelin. , 2004, Blood.
[15] M. Cazzola,et al. Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis. , 2004, Blood.
[16] Herbert Y. Lin,et al. In the Absence of Type III Receptor, the Transforming Growth Factor (TGF)-β Type II-B Receptor Requires the Type I Receptor to Bind TGF-β2* , 2004, Journal of Biological Chemistry.
[17] Elizabeta Nemeth,et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. , 2004, The Journal of clinical investigation.
[18] M. Hentze,et al. Balancing Acts Molecular Control of Mammalian Iron Metabolism , 2004, Cell.
[19] C. Woolf,et al. DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties , 2004, The Journal of Neuroscience.
[20] S. Arber,et al. Repulsive Guidance Molecule (RGM) Gene Function Is Required for Neural Tube Closure But Not Retinal Topography in the Mouse Visual System , 2004, The Journal of Neuroscience.
[21] J. Massagué,et al. Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus , 2003, Cell.
[22] Elizabeta Nemeth,et al. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. , 2003, Blood.
[23] Guang-Quan Zhao,et al. Consequences of knocking out BMP signaling in the mouse , 2003, Genesis.
[24] Markus Affolter,et al. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin , 2002, Nature.
[25] D. Gilot,et al. C/EBPα Regulates Hepatic Transcription of Hepcidin, an Antimicrobial Peptide and Regulator of Iron Metabolism , 2002, The Journal of Biological Chemistry.
[26] W. Van Hul,et al. Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. , 2002, Developmental biology.
[27] Gaël Nicolas,et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. , 2002, The Journal of clinical investigation.
[28] Matthias Mann,et al. RGM is a repulsive guidance molecule for retinal axons , 2002, Nature.
[29] P. ten Dijke,et al. Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter* , 2002, The Journal of Biological Chemistry.
[30] P. Schirmacher,et al. Hepatocellular expression of a dominant-negative mutant TGF-β type II receptor accelerates chemically induced hepatocarcinogenesis , 2001, Oncogene.
[31] C. Beaumont,et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[32] P. Donahoe,et al. Müllerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression. , 2001, Molecular endocrinology.
[33] Christina H. Park,et al. Hepcidin, a Urinary Antimicrobial Peptide Synthesized in the Liver* , 2001, The Journal of Biological Chemistry.
[34] Bruno Turlin,et al. A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload* , 2001, The Journal of Biological Chemistry.
[35] Peter Schulz-Knappe,et al. LEAP‐1, a novel highly disulfide‐bonded human peptide, exhibits antimicrobial activity , 2000, FEBS letters.
[36] P. Hoodless,et al. Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2* , 1998, The Journal of Biological Chemistry.
[37] Denis Vivien,et al. Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene , 1998, The EMBO journal.
[38] G. Ramadori,et al. Bone morphogenetic protein-6 is expressed in nonparenchymal liver cells and upregulated by transforming growth factor-beta 1. , 1997, Experimental cell research.
[39] V. Rogiers,et al. Transforming growth factor-β gene expression in normal and fibrotic rat liver , 1997 .
[40] B. Hogan,et al. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. , 1996, Genes & development.
[41] N. LaRusso,et al. Recent advances in the isolation of liver cells , 1994, Hepatology.
[42] M. Sporn,et al. Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts. , 1984, The Journal of biological chemistry.
[43] A. Minty,et al. Comparison of three actin-coding sequences in the mouse; Evolutionary relationships between the actin genes of warm-blooded vertebrates , 2005, Journal of Molecular Evolution.
[44] T. Ganz,et al. Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. , 2005, Blood.
[45] Marie-Pierre Dubé,et al. Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis , 2004, Nature Genetics.
[46] Seppo Parkkila,et al. Hepatic and extrahepatic expression of the new iron regulatory protein hemojuvelin. , 2004, Haematologica.
[47] Herbert Y. Lin,et al. In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2. , 2004, The Journal of biological chemistry.
[48] J. Massagué,et al. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. , 2003, Cell.
[49] D. Girelli,et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis , 2003, Nature Genetics.
[50] D. Gilot,et al. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. , 2002, The Journal of biological chemistry.
[51] N. Rosenblum,et al. BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways. , 2001, American journal of physiology. Renal physiology.
[52] R. Eisenstein. Iron regulatory proteins and the molecular control of mammalian iron metabolism. , 2000, Annual review of nutrition.
[53] V. Rogiers,et al. Transforming growth factor-beta gene expression in normal and fibrotic rat liver. , 1997, Journal of hepatology.
[54] D. Kingsley,et al. What do BMPs do in mammals? Clues from the mouse short-ear mutation. , 1994, Trends in genetics : TIG.