论文信息 - Modifications induced on the amygdaloid paroxysmal activity by entopeduncolar or nigral injection of kainic acid, in the cat.

Modifications induced on the amygdaloid paroxysmal activity by entopeduncolar or nigral injection of kainic acid, in the cat.

Entopeduncolar or nigral injection of kainic acid determines an early decrease of the evoked amygdaloid paroxysmal activity and a later increase of the after discharge duration. This biphasic effect is likely due to the structural analogy of the drug with monosodium glutamate, a neuroexcitant amino acid. The data suggest that the basal ganglia exert a tonic control on the amygdaloid activity.

G. Crescimanno | A. Benigno | V. Raieli

[1] V. Grutta,et al. Relationship between the striatal system and amygdaloid paroxysmal activity , 1982, Experimental Neurology.

[2] J. Coyle,et al. Local and distant neuronal degeneration following intrastriatal injection of kainic acid. , 1980, Journal of neuropathology and experimental neurology.

[3] J. Coyle,et al. In situ injection of kainic acid: A new method for selectively lesioning neuronal cell bodies while sparing axons of passage , 1978, The Journal of comparative neurology.

[4] K. E. Moore,et al. A histological study of kainic acid-induced lesions in the rat brain , 1978, Brain Research.

[5] H. Fibiger,et al. The use of kainic acid in the localization of enzymes in the substantia nigra , 1978, Brain Research.

[6] J. Olney,et al. Kainic acid: a powerful neurotoxic analogue of glutamate. , 1974, Brain research.

[7] G. Amato,et al. [The importance of the caudate nucleus in the control of convulsive activity in the amygdaloid complex and the temporal cortex of the cat]. , 1971, Electroencephalography and clinical neurophysiology.

[8] H Shinozaki,et al. Actions of several anthelmintics and insecticides on rat cortical neurones. , 1970, Brain research.