Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets

[1]  D. Smith,et al.  Glucagon-like peptide-1 is a physiological incretin in rat. , 1995, The Journal of clinical investigation.

[2]  Q. Duh,et al.  Desensitization of adenylate cyclase in Chinese hamster ovary cells transfected with human thyroid-stimulating hormone receptor. , 1994, Endocrinology.

[3]  S. G. Laychock Sp-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-cyclic monophosphorothioate is a potent stimulus for insulin release. , 1993, Endocrine research.

[4]  H. Imura,et al.  Role of Cytosolic Ca2+ in Impaired Sensitivity to Glucose of Rat Pancreatic Islets Exposed to High Glucose In Vitro , 1992, Diabetes.

[5]  D. Cooper,et al.  The effects of Ca2+ and calmodulin on adenylyl cyclase activity in plasma membranes derived from neural and non-neural cells. , 1992, Cell calcium.

[6]  R. Iyengar,et al.  Heterologous desensitization of the liver adenylyl cyclase: analysis of the role of G-proteins. , 1989, Endocrinology.

[7]  S. Shenolikar,et al.  Cell‐free heterologous desensitization of adenylyl cyclase in S49 lymphoma cell membranes mediated by cAMP‐dependent protein kinase , 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[8]  A. Rajan,et al.  Effect of Rise in cAMP Levels on Ca2+ Influx Through Voltage-Dependent Ca2+ Channels in HIT Cells: Second-Messenger Synarchy in β-Cells , 1989, Diabetes.

[9]  O. Korsgren,et al.  Effects of Hyperglycemia on Function of Isolated Mouse Pancreatic Islets Transplanted Under Kidney Capsule , 1989, Diabetes.

[10]  R. Iyengar,et al.  Glucagon-induced desensitization of adenylyl cyclase in primary cultures of chick hepatocytes. Evidence for multiple pathways. , 1988, The Journal of biological chemistry.

[11]  S. O’Rahilly,et al.  Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. , 1988, The New England journal of medicine.

[12]  G. Grodsky,et al.  Characteristics of desensitization of insulin secretion in fully in vitro systems. , 1988, Endocrinology.

[13]  J. Leahy,et al.  Evolution of Abnormal Insulin Secretory Responses During 48-h In Vivo Hyperglycemia , 1988, Diabetes.

[14]  David R. Sibley,et al.  Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model , 1985, Nature.

[15]  D. Pipeleers,et al.  Regulation of adenosine 3',5'-monophosphate levels in the pancreatic B cell. , 1985, Endocrinology.

[16]  W. Malaisse,et al.  Forskolin-induced activation of adenylate cyclase, cyclic adenosine monophosphate production and insulin release in rat pancreatic islets. , 1984, Endocrinology.

[17]  G. Sharp,et al.  EFFECTS OF FORSKOUN ON INSULIN RELEASE AND CYCLIC AMP CONTENT IN RAT PANCREATIC ISLETS , 1983 .

[18]  R. Iyengar,et al.  Human chorionic gonadotropin-induced heterologous desensitization of adenylyl cyclase from highly luteinized rat ovaries: attenuation of regulatory N component activity. , 1983, Endocrinology.

[19]  S. G. Laychock Mediation of insulin release by cGMP and cAMP in a starved animal model , 1983, Molecular and Cellular Endocrinology.

[20]  H. Meissner,et al.  Dibutyryl cyclic AMP triggers Ca2+ influx and Ca2+-dependent electrical activity in pancreatic B cells. , 1983, Biochemical and biophysical research communications.

[21]  I. Campbell,et al.  The role of metabolism in the control of cyclic AMP efflux, cyclic AMP content, and insulin secretion from rat islets of Langerhans , 1982, Bioscience reports.

[22]  S. G. Laychock Evidence for guanosine 3',5'-monophosphate as a putative mediator of insulin secretion from isolated rat islets. , 1981, Endocrinology.

[23]  L. Lipson,et al.  Role of the adenylate cyclase system in altered insulin release from islets of Langerhans of aging rats. , 1981, Acta endocrinologica.

[24]  C. Wollheim,et al.  Stimulation of Adenylate Cyclase by Ca2+ and Calmodulin in Rat Islets of Langerhans: Explanation for the Glucose-induced Increase in Cyclic AMP Levels , 1980, Diabetes.

[25]  W. Malaisse,et al.  Calmodulin activation of adenylate cyclase in pancreatic islets. , 1979, Science.

[26]  H. Hahn,et al.  Glucose‐dependent effect of methylxanthines on the 45Ca distribution in pancreatic β‐cells , 1979 .

[27]  E. Cerasi,et al.  Glucose-induced Proinsulin Biosynthesis Role of Islet Cyclic AMP , 1977, Diabetes.

[28]  W. Malaisse,et al.  A possible role for the adenylcyclase system in insulin secretion. , 1967, The Journal of clinical investigation.