Hard X-ray-induced optical luminescence via biomolecule-directed metal clusters.

Here, we demonstrate that biomolecule-directed metal clusters are applicable in the study of hard X-ray excited optical luminescence, promising a new direction in the development of novel X-ray-activated imaging probes.

[1]  Robert M Dickson,et al.  Highly fluorescent noble-metal quantum dots. , 2007, Annual review of physical chemistry.

[2]  Lei Xing,et al.  Tomographic molecular imaging of x-ray-excitable nanoparticles. , 2010, Optics letters.

[3]  Kemin Wang,et al.  Ultrasmall near-infrared gold nanoclusters for tumor fluorescence imaging in vivo. , 2010, Nanoscale.

[4]  R. Dickson,et al.  Tailoring silver nanodots for intracellular staining , 2011, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[5]  Wei-Yu Chen,et al.  Use of fluorescent DNA-templated gold/silver nanoclusters for the detection of sulfide ions. , 2011, Analytical chemistry.

[6]  R. Rosenberg,et al.  Visible Emission from GeO2 Nanowires: Site-Specific Insights via X-ray Excited Optical Luminescence , 2012 .

[7]  Samuel Woojoo Jun,et al.  Large-scale synthesis of bioinert tantalum oxide nanoparticles for X-ray computed tomography imaging and bimodal image-guided sentinel lymph node mapping. , 2011, Journal of the American Chemical Society.

[8]  Lei Xing,et al.  Synthesis and Radioluminescence of PEGylated Eu3+‐doped Nanophosphors as Bioimaging Probes , 2011, Advanced materials.

[9]  W. Tseng,et al.  (Lysozyme type VI)-stabilized Au8 clusters: synthesis mechanism and application for sensing of glutathione in a single drop of blood. , 2012, Small.

[10]  Jeffrey N Anker,et al.  Optical imaging in tissue with X-ray excited luminescent sensors. , 2011, The Analyst.

[11]  V. Ntziachristos,et al.  FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography–X-ray computed tomography , 2012, Nature Methods.

[12]  Robert M Dickson,et al.  DNA-Templated Molecular Silver Fluorophores. , 2013, The journal of physical chemistry letters.

[13]  Lei Xing,et al.  X-ray excitable luminescent polymer dots doped with an iridium(III) complex. , 2013, Chemical communications.

[14]  T. Sham,et al.  X-ray-excited optical luminescence (XEOL) and X-ray absorption fine structures (XAFS) studies of gold(I) complexes with diphosphine and bipyridine ligands. , 2007, Inorganic chemistry.

[15]  Zhiqiang Yang,et al.  High-resolution chemical imaging through tissue with an X-ray scintillator sensor. , 2011, Analytical chemistry.

[16]  A. D. Watson,et al.  Metal-Based X-ray Contrast Media. , 1999, Chemical reviews.

[17]  Jianping Xie,et al.  Protein-directed synthesis of highly fluorescent gold nanoclusters. , 2009, Journal of the American Chemical Society.

[18]  S. Qin,et al.  Gold nanoclusters as contrast agents for fluorescent and X-ray dual-modality imaging. , 2012, Journal of colloid and interface science.

[19]  Jan Grimm,et al.  An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles , 2006, Nature materials.

[20]  Y. Hsiao,et al.  Insulin-directed synthesis of fluorescent gold nanoclusters: preservation of insulin bioactivity and versatility in cell imaging. , 2011, Angewandte Chemie.

[21]  Tom Vosch,et al.  Oligonucleotide-stabilized Ag nanocluster fluorophores. , 2008, Journal of the American Chemical Society.

[22]  Jeffrey N Anker,et al.  Advances in functional X-ray imaging techniques and contrast agents. , 2012, Physical chemistry chemical physics : PCCP.

[23]  N. Kosugi,et al.  The chemical bond in carbonyl and sulfinyl groups studied by soft X-ray spectroscopy and ab initio calculations. , 2012, Chemphyschem : a European journal of chemical physics and physical chemistry.

[24]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[25]  R. Rosenberg,et al.  Time-resolved synchrotron radiation excited optical luminescence: light-emission properties of silicon-based nanostructures. , 2007, Chemphyschem : a European journal of chemical physics and physical chemistry.

[26]  R. Gordon,et al.  RIXS, XEOL and XEOL Imaging of Rare-earth Phosphors at the L3,2-edges , 2010 .

[27]  G. Nienhaus,et al.  Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications , 2011 .

[28]  Juewen Liu,et al.  Blue emitting gold nanoclusters templated by poly-cytosine DNA at low pH and poly-adenine DNA at neutral pH. , 2012, Chemical communications.