Accuracy, precision and user-acceptability of self blood glucose monitoring machines.

The performance of six self-monitoring blood glucose (SMBG) machines (Accutrend, Reflolux S, Companion 2, Glucometer GX, Glucometer IV and One Touch II) were examined using venous blood samples from 88 patients. Whole blood glucose (BG) values were measured by four machines from each brand. Machine-generated whole blood glucose (BG) values were corrected before comparison with laboratory plasma glucose values, measured by a glucose oxidase method. Based on error grid analysis, most of the corrected machine-generated BG values were clinically acceptable. Accutrend, Glucometer IV and Companion 2 showed the greatest consistency between machines of the same brand. Over 80% of corrected BG values generated by Glucometer IV fell within +/-10% of the reference values. One Touch II yielded the most reproducible results with a mean CV of 2.7% and was considered the most user friendly machine. More studies are required to examine the performance of these machines in the hands of patients.

[1]  Rupert G. Miller.  Simultaneous Statistical Inference , 1966 .

[2]  R. Lenke,et al.  Comparison of the Accuracy of Glucose Reflectance Meters in Pregnant Insulin- Dependent Diabetics , 1991, Obstetrics and gynecology.

[3]  M G Bissell,et al.  Accuracy of portable blood glucose monitoring. Effect of glucose level and prandial state. , 1991, American journal of clinical pathology.

[4]  D. Cox,et al.  Evaluating Clinical Accuracy of Systems for Self-Monitoring of Blood Glucose , 1987, Diabetes Care.

[5]  G. Leroux-Roels,et al.  Laboratory Assessment of Five Glucose Meters Designed for Self-Monitoring of Blood Glucose Concentration , 1993, European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies.

[6]  T. W. Anderson.  An Introduction to Multivariate Statistical Analysis , 1959 .

[7]  M. Davidson,et al.  Diabetes mellitus, diagnosis and treatment , 1981 .

[8]  W. Moore,et al.  Comparison of Five Glucose Meters for Self-Monitoring of Blood Glucose by Diabetic Patients , 1986, Diabetes Care.

[9]  R. Swaminathan,et al.  Effectiveness of sodium fluoride as a preservative of glucose in blood. , 1989, Clinical chemistry.

[10]  S. Genuth,et al.  The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. , 1993, The New England journal of medicine.

[11]  Virginia A. Clark,et al.  Applied Statistics: Analysis of Variance and Regression. , 1988 .

[12]  Tate Pf,et al.  Accuracy of Home Blood Glucose Monitors , 1992 .