ALS: astrocytes move in as deadly neighbors

[1]  J. Julien,et al.  Wild‐type superoxide dismutase acquires binding and toxic properties of ALS‐linked mutant forms through oxidation , 2007, Journal of neurochemistry.

[2]  Hynek Wichterle,et al.  Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons , 2007, Nature Neuroscience.

[3]  Kevin Eggan,et al.  Non–cell autonomous effect of glia on motor neurons in an embryonic stem cell–based ALS model , 2007, Nature Neuroscience.

[4]  J. Julien,et al.  Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis , 2007, Proceedings of the National Academy of Sciences.

[5]  F. Gage,et al.  Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis , 2006, Proceedings of the National Academy of Sciences.

[6]  J. Julien,et al.  Absence of Tumor Necrosis Factor-α Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutations , 2006, The Journal of Neuroscience.

[7]  S. Mckercher,et al.  Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis , 2006, Proceedings of the National Academy of Sciences.

[8]  R. Oppenheim,et al.  Complete Dissociation of Motor Neuron Death from Motor Dysfunction by Bax Deletion in a Mouse Model of ALS , 2006, The Journal of Neuroscience.

[9]  G. Kollias,et al.  Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia , 2006, Science.

[10]  Minh N. H. Nguyen,et al.  Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice , 2003, Science.

[11]  Jean-Pierre Julien,et al.  Efficient three‐drug cocktail for disease induced by mutant superoxide dismutase , 2003, Annals of neurology.

[12]  Minh N. H. Nguyen,et al.  Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin‐1β in neurodegeneration , 2001, Annals of neurology.

[13]  W. Snider,et al.  Restricted Expression of G86R Cu/Zn Superoxide Dismutase in Astrocytes Results in Astrocytosis But Does Not Cause Motoneuron Degeneration , 2000, The Journal of Neuroscience.

[14]  J. Haines,et al.  Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis , 1993, Nature.

[15]  A. Sik,et al.  Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis , 2006, Nature Neuroscience.