Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27)

[1]  M. Stoffel,et al.  Tmem27 dimerization, deglycosylation, plasma membrane depletion, and the extracellular Phe-Phe motif are negative regulators of cleavage by Bace2 , 2012, Biological chemistry.

[2]  R. Aebersold,et al.  Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass. , 2011, Cell metabolism.

[3]  Edoardo Charbon,et al.  Hybrid Small Animal Imaging System Combining Magnetic Resonance Imaging With Fluorescence Tomography Using Single Photon Avalanche Diode Detectors , 2011, IEEE Transactions on Medical Imaging.

[4]  R. Gomis,et al.  The role of transmembrane protein 27 (TMEM27) in islet physiology and its potential use as a beta cell mass biomarker , 2010, Diabetologia.

[5]  Scott C Davis,et al.  Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications. , 2010, Journal of photochemistry and photobiology. B, Biology.

[6]  G. V. van Dongen,et al.  p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging , 2009, European Journal of Nuclear Medicine and Molecular Imaging.

[7]  D. Stoffers,et al.  Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion. , 2009, Molecular endocrinology.

[8]  M. Karaca,et al.  Functional pancreatic beta-cell mass: involvement in type 2 diabetes and therapeutic intervention. , 2009, Diabetes & metabolism.

[9]  S. Schneider.  Efforts to develop methods for in vivo evaluation of the native β‐cell mass , 2008, Diabetes, obesity & metabolism.

[10]  U. Ahlgren,et al.  Imaging the pancreas: from ex vivo to non-invasive technology , 2008, Diabetologia.

[11]  E. Bernal-Mizrachi,et al.  β-cell failure as a complication of diabetes , 2008, Reviews in Endocrine and Metabolic Disorders.

[12]  P. Antich,et al.  Advances in molecular imaging of pancreatic beta cells. , 2008, Frontiers in bioscience : a journal and virtual library.

[13]  G. Morahan,et al.  Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin , 2008, Diabetologia.

[14]  R. Schibli,et al.  Production and separation of ''non-standard'' PET nuclides at a large cyclotron facility: the experiences at the Paul Scherrer Institute in Switzerland. , 2008, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....

[15]  Mark Muzi,et al.  Tumor-Specific Positron Emission Tomography Imaging in Patients: [18F] Fluorodeoxyglucose and Beyond , 2007, Clinical Cancer Research.

[16]  Parvez Hossain,et al.  Obesity and diabetes in the developing world--a growing challenge. , 2007, The New England journal of medicine.

[17]  K. Herold,et al.  Visualizing pancreatic β-cell mass with [11C]DTBZ , 2006 .

[18]  M. Freeby,et al.  Current progress in non-invasive imaging of beta cell mass of the endocrine pancreas. , 2006, Current medicinal chemistry.

[19]  E. Jansen,et al.  Current status of imaging pancreatic islets , 2006, Current diabetes reports.

[20]  V. Ntziachristos.  Fluorescence molecular imaging. , 2006, Annual review of biomedical engineering.

[21]  Jan Krützfeldt,et al.  Tmem27: a cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation. , 2005, Cell metabolism.

[22]  H. Kasai,et al.  The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation. , 2005, Cell metabolism.

[23]  G. Radda,et al.  Molecular imaging perspectives , 2005, Journal of The Royal Society Interface.

[24]  R. Weissleder,et al.  Imaging inflammation of the pancreatic islets in type 1 diabetes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[25]  S. Nie,et al.  In vivo cancer targeting and imaging with semiconductor quantum dots , 2004, Nature Biotechnology.

[26]  S. Theander,et al.  Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. , 2004, Endocrinology.

[27]  C. Rhodes,et al.  Pancreatic β-cell growth and survival – a role in obesity-linked type 2 diabetes? , 2002 .

[28]  H. Edlund.  Factors controlling pancreatic cell differentiation and function , 2001, Diabetologia.

[29]  R. Weissleder,et al.  Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. , 2001, Optics letters.

[30]  Hai-yan Wang,et al.  Collectrin, a Collecting Duct-specific Transmembrane Glycoprotein, Is a Novel Homolog of ACE2 and Is Developmentally Regulated in Embryonic Kidneys* , 2001, The Journal of Biological Chemistry.

[31]  J. Gerich.  Is insulin resistance the principal cause of type 2 diabetes? , 1999, Diabetes, obesity & metabolism.

[32]  Haiyan Wang,et al.  Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[33]  C. Milstein,et al.  Continuous cultures of fused cells secreting antibody of predefined specificity , 1975, Nature.

[34]  M. Gotthardt,et al.  Approaches for imaging islets: recent advances and future prospects. , 2010, Advances in experimental medicine and biology.

[35]  R. V. Van Heertum,et al.  Visualizing pancreatic beta-cell mass with [11C]DTBZ. , 2006, Nuclear medicine and biology.

[36]  T. Buchanan.  Pancreatic beta-cell loss and preservation in type 2 diabetes. , 2003, Clinical therapeutics.

[37]  C. Rhodes,et al.  Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes? , 2002, Trends in molecular medicine.