American industry and the U.S. Cardiovascular Clinical Research Enterprise an appropriate analogy?

The report by Kim et al. ([1][1]) in this issue of the Journal documents the increasingly widespread phenomenon of the “offshoring” of clinical research—in this case, clinical trials conducted in foreign countries despite being funded by U.S. taxpayers, administered through grants and

[1]  E. Zerhouni.  Translational and clinical science--time for a new vision. , 2005, The New England journal of medicine.

[2]  Robert M Califf,et al.  Clinical research sites--the underappreciated component of the clinical research system. , 2009, JAMA.

[3]  Gordon R. Bernard,et al.  Reengineering the National Clinical and Translational Research Enterprise: The Strategic Plan of the National Clinical and Translational Science Awards Consortium , 2010, Academic medicine : journal of the Association of American Medical Colleges.

[4]  Charla A Andrews.  Ethical and scientific implications of the globalization of clinical research. , 2009, The New England journal of medicine.

[5]  D. DeMets,et al.  A historical perspective on clinical trials innovation and leadership: where have the academics gone? , 2011, JAMA.

[6]  Robert M Califf,et al.  Linking Scientific Discovery and Better Health for the Nation: The First Three Years of the NIH's Clinical and Translational Science Awards , 2010, Academic medicine : journal of the Association of American Medical Colleges.

[7]  K. Bailey,et al.  Digitalis--a new controversy regarding an old drug. The pitfalls of inappropriate methods. , 1986, Circulation.

[8]  R. Califf,et al.  Scientific evidence underlying the ACC/AHA clinical practice guidelines. , 2009, JAMA.

[9]  R. Califf,et al.  Towards a new order in cardiovascular medicine: re-engineering through global collaboration. , 2010, European heart journal.

[10]  V. Menon,et al.  International participation in cardiovascular randomized controlled trials sponsored by the National Heart, Lung, and Blood Institute. , 2011, Journal of the American College of Cardiology.

[11]  Charles B Cairns,et al.  Ethical and scientific implications of the globalization of clinical research. , 2009, The New England journal of medicine.