Visualizing Sphingosine-1-Phosphate Receptor 1(S1P_1) Signaling During Central Nervous System De- and Remyelination

[1]  Douglas L. Rosene,et al.  Quantitative birefringence microscopy for imaging the structural integrity of CNS myelin following circumscribed cortical injury in the rhesus monkey , 2021, Neurophotonics.

[2]  L. Kappos,et al.  Siponimod and Cognition in Secondary Progressive Multiple Sclerosis , 2020, Neurology.

[3]  M. Rocca,et al.  Siponimod for Cognition in Secondary Progressive Multiple Sclerosis , 2020, Neurology.

[4]  I. Glauche,et al.  Continuous mitotic activity of primitive hematopoietic stem cells in adult mice , 2020, The Journal of experimental medicine.

[5]  T. Hla,et al.  Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy , 2020, Proceedings of the National Academy of Sciences.

[6]  Jie Zhang,et al.  Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging , 2020, Neural regeneration research.

[7]  E. Engleman,et al.  Myeloid sphingosine-1-phosphate receptor 1 is important for CNS autoimmunity and neuroinflammation. , 2019, Journal of autoimmunity.

[8]  B. Gaire,et al.  S1P1 Regulates M1/M2 Polarization toward Brain Injury after Transient Focal Cerebral Ischemia , 2019, Biomolecules & therapeutics.

[9]  Li-Hao Yeh,et al.  Revealing architectural order with quantitative label-free imaging and deep learning , 2019, bioRxiv.

[10]  Robert C Reiner,et al.  Global, regional, and national burden of multiple sclerosis 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 , 2019, The Lancet Neurology.

[11]  H. Baharvand,et al.  Fingolimod Enhances Oligodendrocyte Differentiation of Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitors , 2018, Iranian journal of pharmaceutical research : IJPR.

[12]  M. Mayford,et al.  A Functionally Defined In Vivo Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (ieAstrocytes) , 2018, eNeuro.

[13]  V. Natarajan,et al.  Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine‐1‐phosphate signaling in epigenetic regulation of inflammation and gene expression , 2018, Journal of cellular biochemistry.

[14]  D. Theil,et al.  Fingolimod inhibits brain atrophy and promotes brain-derived neurotrophic factor in an animal model of multiple sclerosis , 2018, Journal of Neuroimmunology.

[15]  Clare Baecher-Allan,et al.  Multiple Sclerosis: Mechanisms and Immunotherapy , 2018, Neuron.

[16]  Aijun Wang,et al.  Sox2 Is Essential for Oligodendroglial Proliferation and Differentiation during Postnatal Brain Myelination and CNS Remyelination , 2018, The Journal of Neuroscience.

[17]  S. Shenoy,et al.  G Protein–Coupled Receptor Signaling Through &bgr;-Arrestin–Dependent Mechanisms , 2017, Journal of cardiovascular pharmacology.

[18]  C. Heidecke,et al.  Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration , 2017, BioMed research international.

[19]  M. Barnett,et al.  Effect of Fingolimod on Brain Volume Loss in Patients with Multiple Sclerosis , 2017, CNS Drugs.

[20]  S. Pyne,et al.  Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells , 2017, Molecules.

[21]  Jack Antel,et al.  Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation , 2017, Proceedings of the National Academy of Sciences.

[22]  K. Dev,et al.  Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases , 2017, Neuropharmacology.

[23]  D. Centonze,et al.  Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis , 2016, Journal of Neuroinflammation.

[24]  M. Han,et al.  Effects of sphingosine-1-phosphate receptor 1 phosphorylation in response to FTY720 during neuroinflammation. , 2016, JCI insight.

[25]  H. Hartung,et al.  Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling , 2016, Journal of Neuroinflammation.

[26]  Jens Hjerling-Leffler,et al.  Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system , 2016, Science.

[27]  B. Knöll,et al.  The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration , 2016, Experimental Neurology.

[28]  B. Soliven,et al.  S1P1 deletion in oligodendroglial lineage cells: Effect on differentiation and myelination , 2016, Glia.

[29]  B. Khatri.  Fingolimod in the treatment of relapsing–remitting multiple sclerosis: long-term experience and an update on the clinical evidence , 2016, Therapeutic advances in neurological disorders.

[30]  H. Monyer,et al.  Downregulation of Sphingosine 1-Phosphate Receptor 1 Promotes the Switch from Tangential to Radial Migration in the OB , 2015, The Journal of Neuroscience.

[31]  N. Seki,et al.  IL-17–Producing Vγ4+ γδ T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions , 2015, The Journal of Immunology.

[32]  R. Proia,et al.  Imaging S1P1 activation in vivo. , 2015, Experimental cell research.

[33]  Samuel Bernard,et al.  Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain , 2014, Cell.

[34]  T. Hla,et al.  An update on the biology of sphingosine 1-phosphate receptors , 2014, Journal of Lipid Research.

[35]  J. Gilley,et al.  Wallerian degeneration: an emerging axon death pathway linking injury and disease , 2014 .

[36]  R. Proia,et al.  Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo. , 2014, The Journal of clinical investigation.

[37]  Yasuyuki Kihara,et al.  Fingolimod: Direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy , 2013, Journal of the Neurological Sciences.

[38]  A. Suzumura,et al.  Fingolimod phosphate promotes the neuroprotective effects of microglia , 2013, Journal of Neuroimmunology.

[39]  Vikramjeet Singh,et al.  Cuprizone [Bis(Cyclohexylidenehydrazide)] is Selectively Toxic for Mature Oligodendrocytes , 2013, Neurotoxicity Research.

[40]  B. Barres,et al.  Genomic Analysis of Reactive Astrogliosis , 2012, The Journal of Neuroscience.

[41]  J. Cyster,et al.  Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. , 2012, Annual review of immunology.

[42]  T. Hla,et al.  Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors. , 2011, Chemical reviews.

[43]  S. Rotshenker.  Wallerian degeneration: the innate-immune response to traumatic nerve injury , 2011, Journal of Neuroinflammation.

[44]  Marta P Pereira,et al.  Systemic augmentation of αB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation , 2011, Proceedings of the National Academy of Sciences.

[45]  S. Ludwin,et al.  Neurobiological effects of sphingosine 1‐phosphate receptor modulation in the cuprizone model , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[46]  J. Chun,et al.  The neurobiology of sphingosine 1-phosphate signaling and sphingosine 1-phosphate receptor modulators , 2011, Neurology.

[47]  D. Herr,et al.  FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation , 2010, Proceedings of the National Academy of Sciences.

[48]  Y. Sadahira,et al.  Cellular Localization of Sphingosine-1-phosphate Receptor 1 Expression in the Human Central Nervous System , 2010, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[49]  D. Verzijl,et al.  Sphingosine 1‐phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions , 2010, Glia.

[50]  R. Bucki,et al.  Intrathecal increase of sphingosine 1-phosphate at early stage multiple sclerosis , 2010, Neuroscience Letters.

[51]  R. Proia,et al.  S1P1 receptor directs the release of immature B cells from bone marrow into blood , 2010, The Journal of experimental medicine.

[52]  V. Natarajan,et al.  Neurons and Oligodendrocytes Recycle Sphingosine 1-Phosphate to Ceramide , 2010, The Journal of Biological Chemistry.

[53]  John H. Zhang,et al.  Activation of Sphingosine 1-Phosphate Receptor-1 by FTY720 Is Neuroprotective After Ischemic Stroke in Rats , 2010, Stroke.

[54]  T. Neumann-Haefelin,et al.  The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. , 2009, Biochemical and biophysical research communications.

[55]  R. Proia,et al.  S1P1 receptor overrides regulatory T cell-mediated immune suppression through Akt-mTOR , 2009, Nature Immunology.

[56]  R. Proia,et al.  The alliance of sphingosine-1-phosphate and its receptors in immunity , 2008, Nature Reviews Immunology.

[57]  R. Proia,et al.  Sphingosine-1-phosphate regulation of mammalian development. , 2008, Biochimica et biophysica acta.

[58]  M. Goodell,et al.  Promiscuous Expression of H2B-GFP Transgene in Hematopoietic Stem Cells , 2008, PloS one.

[59]  J. Antel,et al.  FTY720 modulates human oligodendrocyte progenitor process extension and survival , 2008, Annals of neurology.

[60]  H. J. Kim,et al.  Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells , 2007, Glia.

[61]  Xiaoqin Zhu,et al.  NG2 cells generate both oligodendrocytes and gray matter astrocytes , 2007, Development.

[62]  S. Payne,et al.  The Immunomodulator FTY720 Has a Direct Cytoprotective Effect in Oligodendrocyte Progenitors , 2007, Journal of Pharmacology and Experimental Therapeutics.

[63]  M. Schwab,et al.  Phosphorylated FTY720 promotes astrocyte migration through sphingosine‐1‐phosphate receptors , 2007, Journal of neurochemistry.

[64]  Huan Yu,et al.  Involvement of Sphingosine-1-Phosphate in Glutamate Secretion in Hippocampal Neurons , 2007, Molecular and Cellular Biology.

[65]  T. Ohmori,et al.  Essential Roles of Sphingosine 1‐Phosphate/S1P1 Receptor Axis in the Migration of Neural Stem Cells Toward a Site of Spinal Cord Injury , 2007, Stem cells.

[66]  R. Reynolds,et al.  NG2‐expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult central nervous system , 2005, Journal of anatomy.

[67]  David A. Schoenfeld,et al.  Calculating the power or sample size for the logistic and proportional hazards models , 2005 .

[68]  R. Proia,et al.  Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 , 2004, Nature.

[69]  W. Stallcup,et al.  NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[70]  J. P. Hobson,et al.  Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. , 2000, The Journal of clinical investigation.

[71]  Yutong Zhao,et al.  Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. , 2017, Advances in biological regulation.

[72]  B. de Campos Vidal,et al.  Anisotropic properties of the myelin sheath. , 1980, Acta histochemica.