International Myeloma Working Group molecular classification of multiple myeloma: spotlight review
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B. Barlogie | J. Shaughnessy | G. Morgan | P. L. Bergsagel | R. Fonseca | B. Ness | T. Reiman | S. Chen‐Kiang | A. Neri | L. Pilarski | S. Minvielle | H. Avet-Loiseau | O. Sezer | F. Davies | J. Drach | R. Carrasco | N. Gutiérrez | B. Durie | M. Chesi | B. Durie | S. Minvielle | H. Avet-Loiseau | F. Davies | P. Liebisch | Ruben D Carrasco | A. Stewart | G. Morgan | W. Kuehl | H. Avet‐Loiseau | R. Carrasco | M. Chesi | A. Stewart | A. Stewart | P. Bergsagel
[1] Cheng Li,et al. Prognostic significance of copy-number alterations in multiple myeloma. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[2] F. Zhan,et al. An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma. , 2008, Blood.
[3] C. Croce,et al. MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis , 2008, Proceedings of the National Academy of Sciences.
[4] R. Fonseca,et al. Clinical and biological significance of RAS mutations in multiple myeloma , 2008, Leukemia.
[5] B. Barlogie,et al. Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy. , 2009, Blood.
[6] P. L. Bergsagel,et al. Erratum: Translocation t(4;14) retains prognostic significance even in the setting of high-risk molecular signature (Leukemia (2007) 10.1038/sj.leu.2404934) , 2008 .
[7] B. Barlogie,et al. Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. , 2008, Blood.
[8] P. L. Bergsagel,et al. Translocation t(4;14) retains prognostic significance even in the setting of high-risk molecular signature , 2008, Leukemia.
[9] P. L. Bergsagel,et al. Genetic aberrations and survival in plasma cell leukemia , 2008, Leukemia.
[10] P. L. Bergsagel,et al. Genetic events in the pathogenesis of multiple myeloma. , 2007, Best practice & research. Clinical haematology.
[11] G. Morgan,et al. Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma. , 2007, Blood.
[12] X. Leleu,et al. Hyperdiploidy Is a Common Finding in Monoclonal Gammopathy of Undetermined Significance and Monosomy 13 Is Restricted to These Hyperdiploid Patients , 2007, Clinical Cancer Research.
[13] F. Zhan,et al. Establishment and exploitation of hyperdiploid and non‐hyperdiploid human myeloma cell lines , 2007, British journal of haematology.
[14] Jörg Hackermüller,et al. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. , 2007, Blood.
[15] L. Staudt,et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. , 2007, Cancer cell.
[16] L. Bruhn,et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. , 2007, Cancer cell.
[17] R. Bataille,et al. Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome. , 2007, Blood.
[18] Rafael Fonseca,et al. Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling. , 2007, Cancer research.
[19] C. James,et al. Tumor suppressor p16 methylation in multiple myeloma: biological and clinical implications. , 2007, Blood.
[20] Yongsheng Huang,et al. A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1. , 2006, Blood.
[21] G. Ahmann,et al. Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma , 2006, Leukemia.
[22] D. Esseltine,et al. Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study. , 2006, Blood.
[23] John Crowley,et al. The molecular classification of multiple myeloma. , 2006, Blood.
[24] Irene Ghobrial,et al. 6q deletion discriminates Waldenström macroglobulinemia from IgM monoclonal gammopathy of undetermined significance. , 2006, Cancer genetics and cytogenetics.
[25] Cheng Li,et al. Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma. , 2006, Blood.
[26] Yongsheng Huang,et al. Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation. , 2006, Blood.
[27] G. Morgan,et al. Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma , 2006, Leukemia.
[28] G. Ahmann,et al. Prognostic factors for hyperdiploid-myeloma: effects of chromosome 13 deletions and IgH translocations , 2006, Leukemia.
[29] G. Ahmann,et al. Clinical implication of centrosome amplification in plasma cell neoplasm. , 2006, Blood.
[30] L. Chin,et al. High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients. , 2006, Cancer cell.
[31] G. Ahmann,et al. Ploidy status rarely changes in myeloma patients at disease progression. , 2006, Leukemia research.
[32] T. Therneau,et al. Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma. , 2005, Blood.
[33] S. Trudel,et al. Genetic risk identifies multiple myeloma patients who do not benefit from autologous stem cell transplantation , 2005, Bone Marrow Transplantation.
[34] G. Ahmann,et al. Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy. , 2005, Blood.
[35] G. Ahmann,et al. A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS. , 2005, Blood.
[36] Bart Barlogie,et al. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. , 2005, Blood.
[37] Hong Chang,et al. CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma. , 2004, Blood.
[38] Hong Chang,et al. Multiple myeloma involving central nervous system: high frequency of chromosome 17p13.1 (p53) deletions , 2004, British journal of haematology.
[39] R. Kyle,et al. Drug therapy: Multiple myeloma , 2004 .
[40] D. Reece,et al. p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation. , 2004, Blood.
[41] P. L. Bergsagel,et al. Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma. , 2004, Blood.
[42] D. Reece,et al. The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant , 2004, British journal of haematology.
[43] R. Fonseca,et al. The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma. , 2003, Blood.
[44] P. Moreau,et al. t(11;14) and t(4;14) translocations correlated with mature lymphoplasmacytoid and immature morphology, respectively, in multiple myeloma , 2003, Leukemia.
[45] R. Fonseca. Many and multiple myeloma(s) , 2003, Leukemia.
[46] M. Rue,et al. Clinical and biologic implications of recurrent genomic aberrations in myeloma. , 2003, Blood.
[47] R. Bataille,et al. Translocation t(11;14)(q13;q32) is the hallmark of IgM, IgE, and nonsecretory multiple myeloma variants. , 2003, Blood.
[48] Tony Reiman,et al. In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression. , 2003, Blood.
[49] R. Fonseca,et al. Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma , 2003, Leukemia.
[50] Marcos González,et al. Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival , 2002, British journal of haematology.
[51] G. Ahmann,et al. Genomic abnormalities in monoclonal gammopathy of undetermined significance. , 2002, Blood.
[52] Wenming Chen,et al. Methylation of p16 and p15 genes in multiple myeloma. , 2002, Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih.
[53] R. Fonseca,et al. Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients. , 2002, Blood.
[54] G. Gerrard,et al. Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosis , 2002, British journal of haematology.
[55] R. Bataille,et al. Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation. , 2002, Blood.
[56] P. L. Bergsagel,et al. Multiple myeloma: evolving genetic events and host interactions , 2002, Nature Reviews Cancer.
[57] D. Harrington,et al. Biological and prognostic significance of interphase fluorescence in situ hybridization detection of chromosome 13 abnormalities (delta13) in multiple myeloma: an eastern cooperative oncology group study. , 2002, Cancer research.
[58] G. Ahmann,et al. Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis. , 2001, Blood.
[59] D Puthier,et al. High incidence of N and K‐Ras activating mutations in multiple myeloma and primary plasma cell leukemia at diagnosis , 2001, Human mutation.
[60] R. Fonseca,et al. The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance. , 2001, Blood.
[61] B. Barlogie,et al. Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma , 2001, British journal of haematology.
[62] H. Avet-Loiseau,et al. Chromosome 13 abnormalities in multiple myeloma are mostly monosomy 13. , 2000 .
[63] R. Fonseca,et al. The (11;14)(q13;q32) translocation in multiple myeloma. A morphologic and immunohistochemical study. , 2000, American journal of clinical pathology.
[64] H. Kaufmann,et al. Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization. , 2000, Blood.
[65] R. Bataille,et al. Monosomy 13 is associated with the transition of monoclonal gammopathy of undetermined significance to multiple myeloma. Intergroupe Francophone du Myélome. , 1999, Blood.
[66] R. Bataille,et al. 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma. Intergroupe Francophone du Myélome. , 1999, Cancer research.
[67] M. Fiegl,et al. Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy. , 1998, Blood.
[68] H. Koeffler,et al. Methylation of the p16INK4A gene in multiple myeloma , 1998, British journal of haematology.
[69] C. Bastard,et al. Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases , 1998, Leukemia.
[70] J. Miguel,et al. Prognostic value of numerical chromosome aberrations in multiple myeloma: A FISH analysis of 15 different chromosomes. , 1998, Blood.
[71] B. Barlogie,et al. Jumping translocations of chromosome 1q in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin. , 1998, Blood.
[72] G. Ahmann,et al. A novel three-color, clone-specific fluorescence in situ hybridization procedure for monoclonal gammopathies. , 1998, Cancer genetics and cytogenetics.
[73] J. Decaprio,et al. Characterization of p16(INK4A) expression in multiple myeloma and plasma cell leukemia. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.
[74] E. Schröck,et al. Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3 , 1997, Nature Genetics.
[75] B. Barlogie,et al. Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[76] B. Ness,et al. Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial. , 1996, Blood.
[77] B. Barlogie,et al. Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities. , 1995, Blood.
[78] M. Gordon. Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma , 2009 .
[79] J. San Miguel,et al. Impact of genetic abnormalities on survival after allogeneic hematopoietic stem cell transplantation in multiple myeloma , 2008, Leukemia.
[80] L. Escoda,et al. Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated with adverse prognosis , 2007, Leukemia.
[81] P. Sonneveld,et al. Bortezomib appears to overcome the poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials , 2007, Leukemia.
[82] Marcos González,et al. The association of increased p14ARF/p16INK4a and p15INK4a gene expression with proliferative activity and the clinical course of multiple myeloma. , 2006, Haematologica.
[83] H. Johnsen,et al. Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors. , 2005, Blood.
[84] Medicina Nei Secoli La Redazione. No Abstract Available , 2005 .
[85] H. Kaufmann,et al. Oncogenesis of Multiple Myeloma , 2004 .
[86] B. Quesnel,et al. Different prognostic values of p15(INK4b) and p16(INK4a) gene methylations in multiple myeloma. , 2003, Haematologica.
[87] R. Fonseca,et al. Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q arm or monosomy , 2001, Leukemia.
[88] T. Kinoshita,et al. Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia , 2001, Leukemia.
[89] P. L. Bergsagel,et al. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. , 1998, Blood.