Various data, feature and knowledge fusion strategies and architectures have been developed over the last several years for improving upon the accuracy, robustness and overall effectiveness of anomaly, diagnostic and prognostic technologies. Fusion of relevant sensor data, maintenance database information, and outputs from various diagnostic and prognostic technologies has proven effective in reducing false alarm rates, increasing confidence levels in early fault detection, and predicting time to failure or degraded condition requiring maintenance action. The data fusion strategies discussed in this paper are principally probabilistic or AI-based in nature and are used to aid in directly identifying confidence bounds associated with specific component fault identifications and predictions. Dempster-Shafer fusion, Bayesian inference, fuzzy-logic inference, neural network fusion and simple weighting/voting are the algorithmic approaches that are discussed in this paper. Data fusion architectures such as centralized fusion, autonomous fusion, and hybrid fusion are described in terms of their applicability to fault diagnosis and prognosis. The final goal is to find the optimal combination of measured system data, data fusion algorithms, and associated architectures for obtaining the highest overall prediction/detection confidence levels associated with a specific application. A gas turbine engine test cell sensor validation example is provided in the paper that is specifically related data fusion approaches for test cell sensor validation using Dempster-Shafer fusion.