A base-stable metal-organic framework for sensitive and non-enzymatic electrochemical detection of hydrogen peroxide

Abstract Stability of metal-organic frameworks (MOFs) in aqueous medium and extreme solution conditions (acidic or basic) are important for the development of stable, reproducible, and sensitive electrochemical biosensors. Herein, a base-stable chromium(III) dicarboxylate MOF was synthesized by microwave assisted solvothermal method for non-enzymatic detection of hydrogen peroxide (H2O2). The as-synthesized MOF exhibited excellent base stability without any obvious changes in crystallinity, morphology, and spectroscopic behaviors after base treatment. This MOF-modified glassy carbon electrode showed negligible change in charge transfer resistance at the electrode|electrolyte interface after redox cycling and good catalytic activity for the reduction of H2O2 in 0.1 M NaOH(aq.). The enhanced catalytic activity of H2O2 reduction is enabled by the redox process of CrIII/II in the chromium (III) dicarboxylate. The sensor showed the sensitivity of ca. 11.9 μA mM−1, wide linear range from 25 to 500 μM, and a method detection limit of ca. 3.52 μM. The validation of this sensing platform was evaluated by standard addition method. Thus, the present biosensor could be used for the point of care detection of H2O2.

[1]  Yue Gu,et al.  Boosted Sensor Performance by Surface Modification of Bifunctional rht-Type Metal-Organic Framework with Nanosized Electrochemically Reduced Graphene Oxide. , 2017, ACS applied materials & interfaces.

[2]  B. Lim,et al.  A cholesterol biosensor based on a bi-enzyme immobilized on conducting poly(thionine) film , 2014 .

[3]  H. García,et al.  Electrochemistry of Metal−Organic Frameworks: A Description from the Voltammetry of Microparticles Approach , 2007 .

[4]  Qin Xu,et al.  Ni and NiO Nanoparticles Decorated Metal-Organic Framework Nanosheets: Facile Synthesis and High-Performance Nonenzymatic Glucose Detection in Human Serum. , 2017, ACS applied materials & interfaces.

[5]  Seungwon Jeon,et al.  Determination of Dopamine in the Presence of Ascorbic Acid by Nafion and Single-Walled Carbon Nanotube Film Modified on Carbon Fiber Microelectrode , 2008, Sensors.

[6]  Gérard Férey,et al.  Very Large Breathing Effect in the First Nanoporous Chromium(III)-Based Solids: MIL-53 or CrIII(OH)·{O2C−C6H4−CO2}·{HO2C−C6H4−CO2H}x·H2Oy , 2002 .

[7]  David Farrusseng,et al.  Water adsorption in MOFs: fundamentals and applications. , 2014, Chemical Society reviews.

[8]  E. Haque,et al.  Chemical and thermal stability of isotypic metal-organic frameworks: effect of metal ions. , 2011, Chemistry.

[9]  Jianbin Zheng,et al.  A non-enzymatic electrochemical hydrogen peroxide sensor based on Ag decorated boehmite nanotubes/reduced graphene oxide nanocomposites , 2017 .

[10]  M. Behbahani,et al.  Synthesis, characterization and application of novel lead imprinted polymer nanoparticles as a high selective electrochemical sensor for ultra-trace determination of lead ions in complex matrixes , 2014 .

[11]  Wen Weng,et al.  Simple fabrication of flake-like NH2-MIL-53(Cr) and its application as an electrochemical sensor for the detection of Pb2+ , 2016 .

[12]  Hanif Kazerooni,et al.  Ordered carbohydrate-derived porous carbons immobilized gold nanoparticles as a new electrode material for electrocatalytical oxidation and determination of nicotinamide adenine dinucleotide. , 2014, Biosensors & bioelectronics.

[13]  S. Jhung,et al.  Remarkable adsorption capacity of CuCl2-loaded porous vanadium benzenedicarboxylate for benzothiophene. , 2012, Angewandte Chemie.

[14]  A. Mahmood,et al.  Metal‐Organic Framework‐Based Nanomaterials for Electrocatalysis , 2016 .

[15]  Wei Chen,et al.  Recent advances in graphene-based nanomaterials for fabricating electrochemical hydrogen peroxide sensors. , 2017, Biosensors & bioelectronics.

[16]  Sheng Chen,et al.  Ultrathin metal-organic framework array for efficient electrocatalytic water splitting , 2017, Nature Communications.

[17]  Yan Wang,et al.  A Non-Enzymatic Hydrogen Peroxide Sensor Based on Gold Nanoparticles/Carbon Nanotube/Self-Doped Polyaniline Hollow Spheres , 2014 .

[18]  Daojun Zhang,et al.  3D porous metal-organic framework as an efficient electrocatalyst for nonenzymatic sensing application. , 2015, Talanta.

[19]  Weisheng Liu,et al.  An electrochemical sensor for H2O2 based on a new Co-metal-organic framework modified electrode , 2015 .

[20]  S. Joo,et al.  Annealing-Free Synthesis of K-doped Mixed-Phase TiO2 Nanofibers on Ti Foil for Electrochemical Supercapacitor , 2017 .

[21]  A. Dehghani,et al.  A novel electrochemical sensor based on metal-organic framework for electro-catalytic oxidation of L-cysteine. , 2013, Biosensors & bioelectronics.

[22]  B. Zong,et al.  Ru–B nanoparticles on metal–organic frameworks as excellent catalysts for hydrogenation of benzene to cyclohexane under mild reaction conditions , 2016 .

[23]  Zhangxing He,et al.  A novel electrochemical sensor for glucose detection based on Ag@ZIF-67 nanocomposite , 2018 .

[24]  Yuehuan Li,et al.  An enhanced sensitivity towards H 2 O 2 reduction based on a novel Cu metal–organic framework and acetylene black modified electrode , 2017 .

[25]  M. Behbahani,et al.  Mercapto-ordered carbohydrate-derived porous carbon electrode as a novel electrochemical sensor for simple and sensitive ultra-trace detection of omeprazole in biological samples. , 2015, Materials science & engineering. C, Materials for biological applications.

[26]  M. Behbahani,et al.  Selective and Sensitive Determination of Uranyl Ions in Complex Matrices by Ion Imprinted Polymers-Based Electrochemical Sensor , 2015 .

[27]  Ying-Wei Yang,et al.  Metal–Organic Framework (MOF)‐Based Drug/Cargo Delivery and Cancer Therapy , 2017, Advanced materials.

[28]  Y. Li,et al.  A novel electrochemical sensor of tryptophan based on silver nanoparticles/metal–organic framework composite modified glassy carbon electrode , 2016 .

[29]  M. Behbahani,et al.  Application of magnetic lamotrigine-imprinted polymer nanoparticles as an electrochemical sensor for trace determination of lamotrigine in biological samples , 2016 .

[30]  J. Mathiyarasu,et al.  A reagentless non-enzymatic hydrogen peroxide sensor presented using electrochemically reduced graphene oxide modified glassy carbon electrode. , 2016, Materials science & engineering. C, Materials for biological applications.

[31]  M. Behbahani,et al.  A palladium imprinted polymer for highly selective and sensitive electrochemical determination of ultra-trace of palladium ions , 2014 .

[32]  Nasrin Siraj Lopa,et al.  A glassy carbon electrode modified with poly(2,4-dinitrophenylhydrazine) for simultaneous detection of dihydroxybenzene isomers , 2017, Microchimica Acta.

[33]  M. O'keeffe,et al.  Design and synthesis of an exceptionally stable and highly porous metal-organic framework , 1999, Nature.

[34]  Juan-Yu Yang,et al.  One-step synthesis of a copper-based metal–organic framework–graphene nanocomposite with enhanced electrocatalytic activity , 2015 .

[35]  Yanli Zhou,et al.  The Applications of Metal−Organic Frameworks in Electrochemical Sensors , 2018 .

[36]  M. Behbahani,et al.  Application of a novel electrochemical sensor based on modified siliceous mesocellular foam for electrochemical detection of ultra-trace amounts of mercury ions , 2016 .

[37]  S. Yamamoto,et al.  Determination of hydrogen peroxide in beverages by high-performance liquid chromatography with fluorescence detection. , 1987, Journal of chromatography.

[38]  Wei Chen,et al.  Graphene wrapped Cu2O nanocubes: non-enzymatic electrochemical sensors for the detection of glucose and hydrogen peroxide with enhanced stability. , 2013, Biosensors & bioelectronics.

[39]  Daojun Zhang,et al.  Electrografting of amino-TEMPO on graphene oxide and electrochemically reduced graphene oxide for electrocatalytic applications , 2017 .

[40]  S. Bose,et al.  Recent advances in graphene-based biosensors. , 2011, Biosensors & bioelectronics.

[41]  P. Yang,et al.  Metal-organic frameworks for electrocatalytic reduction of carbon dioxide. , 2015, Journal of the American Chemical Society.

[42]  Joseph Wang.  Carbon‐Nanotube Based Electrochemical Biosensors: A Review , 2005 .

[43]  Feixiang Wu,et al.  Li-ion battery materials: present and future , 2015 .

[44]  M. Omidkhah,et al.  Highly permeable poly(4-methyl-1-pentyne)/NH2-MIL 53 (Al) mixed matrix membrane for CO2/CH4 separation , 2014 .

[45]  Yanfeng Yue,et al.  Luminescent functional metal-organic frameworks. , 2012, Chemical Reviews.

[46]  L. Ai,et al.  Solvothermal synthesis of MIL–53(Fe) hybrid magnetic composites for photoelectrochemical water oxidation and organic pollutant photodegradation under visible light , 2015 .

[47]  Xueming Li,et al.  Non-enzymatic electrochemical sensors for the detection of hydrogen peroxide based on Cu2O/Cu nanocomposites , 2014 .

[48]  P. Pelicci,et al.  Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? , 2007, Nature Reviews Molecular Cell Biology.

[49]  Nasrin Siraj Lopa,et al.  Highly sensitive and simultaneous detection of dopamine and uric acid at graphene nanoplatelet-modified fluorine-doped tin oxide electrode in the presence of ascorbic acid , 2017 .

[50]  Xuebo Zhao,et al.  Oxygen reduction in the nanocage of metal–organic frameworks with an electron transfer mediator , 2014 .

[51]  N. Masuoka,et al.  Spectrophotometric determination of hydrogen peroxide: catalase activity and rates of hydrogen peroxide removal by erythrocytes. , 1996, Clinica chimica acta; international journal of clinical chemistry.

[52]  Yunfeng Shi,et al.  Polyethylenimine-bridged graphene oxide-gold film on glassy carbon electrode and its electrocatalytic activity toward nitrite and hydrogen peroxide , 2014 .

[53]  Chengzhou Zhu,et al.  Electrochemical Sensors and Biosensors Based on Nanomaterials and Nanostructures , 2014, Analytical chemistry.

[54]  Daojun Zhang,et al.  Redox-active microsized metal-organic framework for efficient nonenzymatic H2O2 sensing , 2015 .

[55]  Juan Li,et al.  Amperometric determination of reduced glutathione with a new Co-based metal-organic coordination polymer modified electrode , 2014 .

[56]  S. Hwang,et al.  Non-enzymatic electrochemical CuO nanoflowers sensor for hydrogen peroxide detection. , 2010, Talanta.