Synthetic Chemical Literature
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Several databases track new and improved synthetic methods in organic chemistry. An analysis of the ISI Reaction Center, CASREACT, and ChemInformRX shows a consensus that nearly all new synthetic techniques are found in a core of about 100 sources. In addition, patents were found to be a significant, yet under-used, source of novel chemistry.
[1] Ole V. Groos. Bradford's law and the keenan-atherton data , 1967 .
[2] Johann Gasteiger,et al. ChemInform - an integrated information system on chemical reactions , 1990, J. Chem. Inf. Comput. Sci..
[3] James E. Blake,et al. CASREACT: more than a million reactions , 1990, J. Chem. Inf. Comput. Sci..