Transmission of Alzheimer's disease-associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients.

[1]  R. Vassar,et al.  The gut microbiome in Alzheimer’s disease: what we know and what remains to be explored , 2023, Molecular Neurodegeneration.

[2]  T. Spector,et al.  The person-to-person transmission landscape of the gut and oral microbiomes , 2023, Nature.

[3]  D. Holtzman,et al.  ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy , 2023, Science.

[4]  Nan Wang,et al.  Changes in the Mucosa-Associated Microbiome and Transcriptome across Gut Segments Are Associated with Obesity in a Metabolic Syndrome Porcine Model , 2022, Microbiology spectrum.

[5]  K. Yaffe,et al.  Risk Factors Associated With Alzheimer Disease and Related Dementias by Sex and Race and Ethnicity in the US. , 2022, JAMA neurology.

[6]  H. Wachsmuth,et al.  Role of the gut–brain axis in energy and glucose metabolism , 2022, Experimental & Molecular Medicine.

[7]  K. Kovács,et al.  The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities , 2022, Life.

[8]  Jun R Huh,et al.  Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS , 2022, EBioMedicine.

[9]  C. Abraham,et al.  Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease. , 2022, Gastroenterology.

[10]  F. Sarubbo,et al.  The Influence of Gut Microbiota on Neurogenesis: Evidence and Hopes , 2022, Cells.

[11]  K. Ye,et al.  Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation , 2022, Gut.

[12]  R. Tanzi,et al.  Gut microbiota–driven brain Aβ amyloidosis in mice requires microglia , 2021, The Journal of experimental medicine.

[13]  Z. Zuo,et al.  Appropriate exercise level attenuates gut dysbiosis and valeric acid increase to improve neuroplasticity and cognitive function after surgery in mice , 2021, Molecular Psychiatry.

[14]  M. Do,et al.  Amelioration of Hepatic Steatosis in Mice through Bacteroides uniformis CBA7346-Mediated Regulation of High-Fat Diet-Induced Insulin Resistance and Lipogenesis , 2021, Nutrients.

[15]  D. Schleheck,et al.  Bacterial microcompartments for isethionate desulfonation in the taurine-degrading human-gut bacterium Bilophila wadsworthia , 2021, bioRxiv.

[16]  Lanjuan Li,et al.  The Relationship Between the Gut Microbiome and Neurodegenerative Diseases , 2021, Neuroscience Bulletin.

[17]  A. Mietelska-Porowska,et al.  Western diet as a trigger of Alzheimer’s disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration , 2021, Ageing Research Reviews.

[18]  Tal Frolinger,et al.  Chronic Stress-Induced Depression and Anxiety Priming Modulated by Gut-Brain-Axis Immunity , 2021, Frontiers in Immunology.

[19]  Timothy L. Tickle,et al.  Multivariable association discovery in population-scale meta-omics studies , 2021, bioRxiv.

[20]  M. Frosch,et al.  Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation , 2021, iScience.

[21]  G. Liebisch,et al.  Bacteroides uniformis combined with fiber amplifies metabolic and immune benefits in obese mice , 2021, Gut microbes.

[22]  T. Elamurugan,et al.  Pathogenic potential of Parabacteroides distasonis revealed in a splenic abscess case: a truth unfolded , 2020, BMJ Case Reports.

[23]  M. Meyer-Luehmann,et al.  Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease , 2020, Acta Neuropathologica Communications.

[24]  K. Ye,et al.  Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model , 2020, Science Advances.

[25]  A. Steptoe,et al.  Higher risk of dementia in English older individuals who are overweight or obese , 2020, International journal of epidemiology.

[26]  M. Kano,et al.  Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation , 2020, Neuron.

[27]  H. Dodiya,et al.  Synergistic depletion of gut microbial consortia, but not individual antibiotics, reduces amyloidosis in APPPS1-21 Alzheimer’s transgenic mice , 2020, Scientific Reports.

[28]  I. Tzeng,et al.  Relationship Between Exercise and Alzheimer’s Disease: A Narrative Literature Review , 2020, Frontiers in Neuroscience.

[29]  V. Bacquié,et al.  Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses , 2020, Cellular and molecular gastroenterology and hepatology.

[30]  E. Marcantonio,et al.  Anesthesia and surgery induce age-dependent changes in behaviors and microbiota , 2020, Aging.

[31]  T. Dinan,et al.  Microbiota-Gut-Brain Axis: New Therapeutic Opportunities. , 2020, Annual review of pharmacology and toxicology.

[32]  M. Gulisano,et al.  Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients , 2019, bioRxiv.

[33]  B. Warner,et al.  Discordant transmission of bacteria and viruses from mothers to babies at birth , 2019, Microbiome.

[34]  Jun Yu,et al.  A novel faecal Lachnoclostridium marker for the non-invasive diagnosis of colorectal adenoma and cancer , 2019, Gut.

[35]  D. Holtzman,et al.  Alzheimer Disease: An Update on Pathobiology and Treatment Strategies , 2019, Cell.

[36]  Lanjuan Li,et al.  Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort , 2019, Brain, Behavior, and Immunity.

[37]  J. Gilbert,et al.  Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes , 2019, The Journal of experimental medicine.

[38]  T. Dinan,et al.  Gut Microbe to Brain Signaling: What Happens in Vagus… , 2019, Neuron.

[39]  Katherine H. Huang,et al.  Transmission of human-associated microbiota along family and social networks , 2019, Nature Microbiology.

[40]  C. Glass,et al.  Microbiome–microglia connections via the gut–brain axis , 2018, The Journal of experimental medicine.

[41]  Duy Tin Truong,et al.  Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome , 2018, Cell host & microbe.

[42]  Sterling C. Johnson,et al.  Gut microbiome alterations in Alzheimer’s disease , 2017, Scientific Reports.

[43]  Emiri T. Mandeville,et al.  Anesthesia and Surgery Impair Blood–Brain Barrier and Cognitive Function in Mice , 2017, Front. Immunol..

[44]  D. Kwon,et al.  Gut Microbiota is critical for the induction of chemotherapy-induced pain , 2017, Nature Neuroscience.

[45]  B. Neville,et al.  Transmission of the gut microbiota: spreading of health , 2017, Nature Reviews Microbiology.

[46]  G. Frisoni,et al.  Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota , 2017, Scientific Reports.

[47]  L. Weyandt,et al.  Alzheimer's disease and diet: a systematic review , 2017, The International journal of neuroscience.

[48]  G. Frisoni,et al.  Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly , 2017, Neurobiology of Aging.

[49]  David S. Miller,et al.  Tau: From research to clinical development , 2016, Alzheimer's & Dementia.

[50]  D. Holtzman,et al.  Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease , 2016, Scientific Reports.

[51]  W. Grant,et al.  Using Multicountry Ecological and Observational Studies to Determine Dietary Risk Factors for Alzheimer's Disease , 2016, Journal of the American College of Nutrition.

[52]  Paul Edison,et al.  Neuroinflammation in Alzheimer's disease: Current evidence and future directions , 2016, Alzheimer's & Dementia.

[53]  T. Dinan,et al.  Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior , 2016, The international journal of neuropsychopharmacology.

[54]  Michael J. Barratt,et al.  Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children , 2016, Science.

[55]  I. Gursel,et al.  Intestinal Microbiota in Patients with Spinal Cord Injury , 2016, PloS one.

[56]  E. Mandelkow,et al.  Tau in physiology and pathology , 2015, Nature Reviews Neuroscience.

[57]  R. Nicoll,et al.  PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density , 2015, Proceedings of the National Academy of Sciences.

[58]  K. Kaliannan,et al.  A host-microbiome interaction mediates the opposing effects of omega-6 and omega-3 fatty acids on metabolic endotoxemia , 2015, Scientific Reports.

[59]  Junjie Yu,et al.  Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice , 2015, BioMed research international.

[60]  D. Holtzman,et al.  Three dimensions of the amyloid hypothesis: time, space and 'wingmen' , 2015, Nature Neuroscience.

[61]  Lai Guan Ng,et al.  The gut microbiota influences blood-brain barrier permeability in mice , 2014, Science Translational Medicine.

[62]  H. Heinze,et al.  Vascular hippocampal plasticity after aerobic exercise in older adults , 2014, Molecular Psychiatry.

[63]  F. Bäckhed,et al.  Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits , 2014, Cell.

[64]  R. Vassar,et al.  Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation , 2013, Molecular Neurodegeneration.

[65]  T. Dinan,et al.  Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour , 2012, Nature Reviews Neuroscience.

[66]  E. Marcantonio,et al.  Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory , 2012, Annals of neurology.

[67]  Christine L. Williams Marriage and mental health: when a spouse has Alzheimer's disease. , 2011, Archives of psychiatric nursing.

[68]  M. Vitek,et al.  Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease , 2010, Neuroscience.

[69]  P. Rabins,et al.  Greater Risk of Dementia When Spouse Has Dementia? The Cache County Study , 2010, Journal of the American Geriatrics Society.

[70]  L. Leach,et al.  Cognitive functioning under stress: evidence from informal caregivers of palliative patients. , 2007, Journal of palliative medicine.

[71]  M. Nyman,et al.  Rapid determination of short-chain fatty acids in colonic contents and faeces of humans and rats by acidified water-extraction and direct-injection gas chromatography. , 2006, Biomedical chromatography : BMC.

[72]  J. Jolles,et al.  Cognitive functioning in spousal caregivers of dementia patients: findings from the prospective MAASBED study. , 2006, Age and ageing.

[73]  P. Phillips,et al.  Battelle Centers for Public Health Research and Evaluation , 2005 .

[74]  J R Hodges,et al.  Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia. , 2004, Brain : a journal of neurology.

[75]  F. Grodstein,et al.  Does Caregiving Stress Affect Cognitive Function in Older Women? , 2004, The Journal of nervous and mental disease.

[76]  D. Selkoe Alzheimer's disease: genes, proteins, and therapy. , 2001, Physiological reviews.

[77]  R. Aebersold,et al.  Mass spectrometry in proteomics. , 2001, Chemical reviews.

[78]  J. Galmiche,et al.  Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease. , 2000, Gut.

[79]  H. Wiśniewski,et al.  Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. , 1986, Proceedings of the National Academy of Sciences of the United States of America.