Identification of the central sulcus in adolescents with epilepsy : MEG results confirmed by cortical stimulation of subdural grid

It is important to identify the central sulcus (CS) for epilepsy surgery to avoid postoperative functional deficits in children with medically intractable extratemporal lobe epilepsy. There are many papers focusing on the central sulcus identification [2-6,9,11,12]. Coregistration technique of MEG data and surface rendering MR image can delineate functional magnetic field with brain surface structure. The aim of this study is, to compare the location of CS identified by MSI with the actual CS that was defined with SEP and direct cortical stimulation using subdural grid.

[1]  D. Barth,et al.  MEG and ECoG localization accuracy test. , 1995, Electroencephalography and clinical neurophysiology.

[2]  R D Bucholz,et al.  Presurgical localization of functional cortex using magnetic source imaging. , 1995, Journal of neurosurgery.

[3]  新居康夫,et al.  Does the central sulcus divide motor and sensory functions?Cortical mapping of human hand areas as revealed by electrical stimulation through subdural grid electrodes(硬膜下植え込み電極刺激法による手の大脳皮質運動知覚領野の局在に関する臨床的研究) , 1997 .

[4]  F. Bloom,et al.  Locating the central sulcus: comparison of MR anatomic and magnetoencephalographic functional methods. , 1993, AJNR. American journal of neuroradiology.

[5]  T. Yoshimoto,et al.  Neuromagnetic evidence of pre- and post-central cortical sources of somatosensory evoked responses. , 1996, Electroencephalography and clinical neurophysiology.

[6]  J. Rothwell,et al.  Cortical correlate of the Piper rhythm in humans. , 1998, Journal of neurophysiology.

[7]  Christo Pantev,et al.  Reproducibility and Validity of Neuromagnetic Source Localization Using A Large Array Biomagnetometer , 1991 .

[8]  R P Lesser,et al.  Cortical Afterdischarge and Functional Response Thresholds: Results of Extraoperative Testing , 1984, Epilepsia.

[9]  C. Strauss,et al.  Magnetic source imaging combined with image-guided frameless stereotaxy: a new method in surgery around the motor strip. , 1997, Neurosurgery.

[10]  F E Bloom,et al.  Intrasubject reliability and validity of somatosensory source localization using a large array biomagnetometer. , 1994, Electroencephalography and clinical neurophysiology.

[11]  Juan Bulacio,et al.  Seizure outcome after epilepsy surgery in children and adolescents , 1998, Annals of neurology.

[12]  P H Crandall,et al.  The magnetic and electric fields agree with intracranial localizations of somatosensory cortex , 1988, Neurology.

[13]  W. Penfield,et al.  SOMATIC MOTOR AND SENSORY REPRESENTATION IN THE CEREBRAL CORTEX OF MAN AS STUDIED BY ELECTRICAL STIMULATION , 1937 .