BRAIN PERFUSION SPECT WITH 99M-TC HMPAO IN SPONTANEOUS INTRACEREBRAL HEMORRHAGE

Spontaneous intracerebral hemorrhage has a poor prognosis and is considered the deadliest form of stroke. Many recent studies have shown that there are many mechanisms involved in the pathology of this disease among which one of the most studied and controversial is perilesional ischemia. The aim of our study was to assess the role of brain perfusion SPECT with 99m-Tc HMPAO in demonstrating perfusion changes in brain tissue surrounding hematoma.

[1]  R. Swanson Intracerebral hematoma: beyond the mass lesion. , 2006, Stroke.

[2]  J. Kuratsu,et al.  Serial changes in the regional cerebral blood flow of patients with hypertensive intracerebral hemorrhage -- long-term follow-up SPECT study. , 2005, Journal of neurosurgical sciences.

[3]  R. Keep,et al.  The Deleterious or Beneficial Effects of Different Agents in Intracerebral Hemorrhage: Think Big, Think Small, or Is Hematoma Size Important? , 2005, Stroke.

[4]  W. Hacke,et al.  Stroke MRI in Intracerebral Hemorrhage: Is There a Perihemorrhagic Penumbra? , 2003, Stroke.

[5]  Joseph F. Clark,et al.  Heme and Iron Metabolism: Role in Cerebral Hemorrhage , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[6]  M. Sasaki,et al.  11C-methionine uptake in cerebrovascular disease: A comparison with18F-FDG PET and99mTc-HMPAO SPECT , 2002, Annals of nuclear medicine.

[7]  Piotr Slomka,et al.  Reversible ischemia around intracerebral hemorrhage: a single-photon emission computerized tomography study. , 2002, Journal of neurosurgery.

[8]  R. E. Adams,et al.  Hypoperfusion without Ischemia Surrounding Acute Intracerebral Hemorrhage , 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[9]  H J Tochon-Danguy,et al.  No evidence of hypoxic tissue on 18F-fluoromisonidazole PET after intracerebral hemorrhage , 1999, Neurology.

[10]  R. V. Van Heertum,et al.  Perilesional blood flow and edema formation in acute intracerebral hemorrhage: a SPECT study. , 1998, Stroke.

[11]  T. Chenevert,et al.  Experimental intracerebral hemorrhage: relationship between brain edema, blood flow, and blood-brain barrier permeability in rats. , 1994, Journal of neurosurgery.

[12]  P. Sandercock,et al.  Long‐term Survival After First‐Ever Stroke: The Oxfordshire Community Stroke Project , 1993, Stroke.

[13]  B. Siesjö,et al.  Thresholds in cerebral ischemia - the ischemic penumbra. , 1981, Stroke.

[14]  Harvey Cushing,et al.  SOME EXPERIMENTAL AND OLINICAL OBSERVATIONS CONOERNING STATES OF INCREASED INTRACRANIAL TENSION , 1902 .