论文信息 - Feto-Maternal Alloimmune Thrombocytopenia Associated With Anti-Hpa-5A

Feto-Maternal Alloimmune Thrombocytopenia Associated With Anti-Hpa-5A — The First Australian Case

&NA; Maternal alloantibodies to platelet specific antigens are a rare but important cause of severe thrombocytopenia in the fetus and neonate. Feto-Maternal Alloimmune Thrombocytopenia (FMAT) is most often due to anti-HPA-1a (PLA-1) or anti-HPA-5b (Bra). Anti-HPA-5a (Brb) however is extremely uncommon, with only 4 cases previously described. We report the first Australian case of feto-maternal alloimmune thrombocytopenia due to anti-HPA-5a.

J. Lown | A. Barr | T. Roper | John A. Lown

[1] P. Newman,et al. Molecular genetic aspects of human platelet antigen systems. , 1991, Bailliere's clinical haematology.

[2] J. Lown,et al. Evaluation of a solid phase red cell adherence technique for platelet antibody screening , 1991, Transfusion medicine.

[3] M. Morel-Kopp,et al. HPA‐5b (Bra) neonatal alloimmune thrombocytopenia: clinical and immunological analysis of 39 cases , 1991, British journal of haematology.

[4] C. Mueller-Eckhardt,et al. Neonatal Alloimmune Thrombocytopenia due to Anti‐Brb (HPA‐5a) , 1991, Vox sanguinis.

[5] P. Bierling,et al. Brb, a Platelet Alloantigen Involved in Neonatal Alloimmune Thrombocytopenia , 1991, Vox sanguinis.

[6] C. Mueller-Eckhardt,et al. A New Platelet‐Specific Alloantigen Bra , 1988 .

[7] C. Mueller-Eckhardt,et al. A new platelet-specific alloantigen Bra. Report of 4 cases with neonatal alloimmune thrombocytopenia. , 1988, Vox sanguinis.

[8] R. Nordhagen,et al. Chloroquine Removal of HLA Antigens from Platelets for the Platelet Immunofluorescence Test , 1985, Vox sanguinis.